2-Topping Medium Pizza
$6.99
A custom pizza made to order. Choose from any of our delicious crust styles, excluding Handmade Pan or Paremsan Crust.
Brand Certified
Domino's Pizza
3.4(443 reviews)
Certified by Domino's Pizza • Jul 05, 2026
Business Details
3416 West Palmetto St, Florence, SC
29501, United States
Certified by Domino's Pizza • Jul 05, 2026
(843) 346-1000
Certified by Domino's Pizza • Jul 05, 2026
https://www.dominos.com/en/?utm_source=google&utm_medium=loclist&utm_campaign=localmaps
Certified by Domino's Pizza • Jul 05, 2026
About
Certified by Domino's Pizza • Jul 05, 2026
Pizza RestaurantRestaurant Delivery ServiceTake Out RestaurantFast Food RestaurantDomino's Pizza
Looking for great pizza in Florence? At Domino’s, we’re passionate about bringing you the best pizza experience, whether you're carrying out or ordering pizza delivery. Whether you’re craving thin, foldable New York Style pizza or a thick, Handmade Pan pizza, Domino’s has you covered. Or try our delicious, cheesy Parmesan Stuffed Crust pizza today! We offer more than just mouthwatering pizza—dishes like our fan-favorite mac and cheese, salads, pasta, and chicken wings will satisfy all your needs. We’ll give you great value with our unbeatable deals, making it easy to enjoy more for less. Wherever you are, the Domino's Pizza near you is here to satisfy your cravings with taste and quality. Order from 3416 West Palmetto St .
Details
- Dine-inNot available
- DeliveryAvailable
- TakeoutAvailable
- Credit cardAvailable
Location
Certified by Domino's Pizza • Jul 05, 2026
Hours
Certified by Domino's Pizza • Jul 05, 2026
Monday10:00 AM - 12:00 AM
Tuesday10:00 AM - 12:00 AM
Wednesday10:00 AM - 12:00 AM
Thursday10:00 AM - 12:00 AM
Friday10:00 AM - 1:00 AM
Saturday10:00 AM - 1:00 AM
Sunday10:00 AM - 12:00 AM
Menu
1 menu · 82 items
Explore offerings from Domino's Pizza on 3416 West Palmetto St in Florence, with popular mix and match, pizza, breads, and chicken available at this location.
Test Menu data- all locations
82 items
Mix and Match
Parmesan Bread Bites
$6.99
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan.
Stuffed Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Pepperoni Stuffed Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese and pepperoni - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Spinach & Feta Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese, fresh spinach and Feta cheese - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Bacon & Jalapeño Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese, smoked bacon and jalapeno peppers - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an addional charge.
Boneless Chicken
$6.99
Breaded chicken made with 100% whole white breast meat. Choose one or more dipping cups for an additional charge.
Hot Buffalo Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with hot buffalo sauce, ranch, a blend of cheese made with mozzarella and cheddar, and feta.
Sweet BBQ Bacon Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with sweet and smoky honey BBQ sauce, a blend of cheese made with mozzarella and cheddar, and crispy bacon.
Crispy Bacon & Tomato Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with garlic Parmesan sauce, a blend of cheese made with mozzarella and cheddar, crispy bacon and tomato.
Spicy Jalapeno-Pineapple Loaded Chicken
$6.99
Tender bites of lightly breaded, 100% whole breast white meat chicken, topped with sweet and spicy mango-habanero sauce, a blend of cheese made with mozzarella and cheddar, jalapeno and pineapple.
5-Cheese Mac & Cheese
$6.99
Our take on the classic. Penne pasta and a blend of cheddar, American, Parmesan-Asiago, mozzarella blend and Alfredo sauce, oven baked to creamy, bubbly perfection.
Spicy Buffalo 5-Cheese Mac & Cheese
$6.99
Our creamy, oven baked 5-cheese Mac & Cheese drizzled with buffalo sauce for a spicy kick.
Chicken Alfredo
$6.99
Grilled chicken breast and creamy Alfredo sauce mixed with penne pasta and baked to perfection.
Philly Cheese Steak
$6.99
Tender slices of steak, American and provolone cheeses, fresh onions, fresh green peppers and fresh mushrooms.
Chicken Bacon Ranch
$6.99
Grilled chicken breast topped with smoked bacon, creamy ranch and provolone cheese.
Italian
$6.99
Pepperoni and ham topped with banana peppers, fresh green peppers, fresh onions and provolone cheese.
Chicken Parm
$6.99
Grilled chicken breast, tomato-basil marinara, Parmesan- Asiago and provolone cheeses.
Buffalo Chicken
$6.99
Grilled chicken breast, ranch, fresh onions, hot buffalo sauce, provolone, cheddar and cheese made with 100% real mozzarella.
Classic Garden
$6.99
A crisp and colorful combination of grape tomatoes, red onions, carrots, red cabbage, cheddar cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Chicken Caesar
$6.99
The makings of a classic: roasted white meat chicken, Parmesan cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Cinnamon Bread Bites
$6.99
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Domino's Marbled Cookie Brownie
$6.99
An irresistibly warn and gooey blend of milk chocolate chunk cookie and fudge brownie. This sharable dessert is oven baked at the time of order and cut into 9 pieces.
Chocolate Lava Crunch Cakes
$6.99
Oven-baked chocolate cakes, crunchy on the outside with molten chocolate fudge on the inside.
Pizza
Spicy Chicken Bacon Ranch
Grilled chicken breast, creamy ranch, smoked bacon, jalapeños, provolone, and cheese made with 100% real mozzarella and finished off with a drizzle of buffalo sauce.
ExtravaganZZa ™
Pepperoni, ham, Italian sausage, beef, fresh onions, fresh green peppers, fresh mushrooms and black olives, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
MeatZZa™
Pepperoni, ham, Italian sausage and beef, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
Philly Cheese Steak
Tender slices of steak, fresh onions, fresh green peppers, fresh mushrooms, provolone and American cheese.
Honolulu Hawaiian
Sliced Ham, smoked bacon, pineapple, fresh green peppers, provolone and cheese made with 100% real mozzarella.
Pacific Veggie
Fresh spinach, fresh onions, fresh mushrooms, fresh onions, provolone and cheese made with 100% real mozzarella.
The People’s Pizza – Deluxe
Savory pepperoni and Italian sausage, fresh green peppers, fresh mushrooms, fresh onions, provolone and cheese made with 100% real mozzarella. We’ve combined our customers’ most ordered toppings into the perfect deluxe pizza.
Ultimate Pepperoni
Two layers of pepperoni sandwiched between provolone, Parmesan-Asiago and cheese made with 100% real mozzarella, then sprinkled with oregano.
Memphis BBQ Chicken
Grilled chicken breast, fresh onions, provolone, American cheese, cheddar, cheese made with 100% real mozzarella.
Wisconsin 6-Cheese
Feta, provolone, cheddar, Parmesan-Asiago, cheese made with 100% real mozzarella, then sprinkled with oregano.
Spinach & Feta
Creamy Alfredo sauce, fresh spinach, fresh onions, feta, Parmesan-Asiago, provolone and cheese made with 100% real mozzarella.
Build Your Own
A custom pizza made to order. Choose from any of our delicious crust styles, including Handmade Pan or Parmesan Stuffed Crust.
Breads
Parmesan Bread Bites
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan.
Cinnamon Bread Bites
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Stuffed Cheesy Bread
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Pepperoni Stuffed Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese and pepperoni - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Spinach & Feta Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese, fresh spinach and Feta cheese - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Bacon & Jalapeño Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese, smoked bacon and jalapeno peppers - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Chicken
Boneless Chicken
Breaded chicken made with 100% whole white breast meat. Choose one or more dipping cups for an additional charge.
Bone-in Wings
Marinated and oven-baked. Customize with your choice of dipping cup.
Hot Buffalo Bone-in Wings
Marinated and oven-baked, then smothered in hot buffalo sauce. Customize with your choice of dipping cup.
Honey BBQ Bone-in Wings
Marinated and oven-baked, then smothered in honey BBQ sauce. Customize with your choice of dipping cup.
Garlic Parmesan Bone-in Wings
Marinated and oven-baked, then smothered in garlic Parmesan sauce. Customize with your choice of dipping cup.
Sweet Mango Habanero Bone-in Wings
Marinated and oven-baked, then smothered in sweet mango habanero sauce. Customize with your choice of dipping cup.
Hot Buffalo Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with hot buffalo sauce, ranch, a blend of cheese made with mozzarella and cheddar, and feta.
Sweet BBQ Bacon Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with sweet and smoky honey BBQ sauce, a blend of cheese made with mozzarella and cheddar, and crispy bacon.
Crispy Bacon & Tomato Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with garlic Parmesan sauce, a blend of cheese made with mozzarella and cheddar, crispy bacon and tomato.
Spicy Jalapeno-Pineapple Loaded Chicken
Tender bites of lightly breaded, 100% whole breast white meat chicken, topped with sweet and spicy mango-habanero sauce, a blend of cheese made with mozzarella and cheddar, jalapeno and pineapple.
Pastas
5-Cheese Mac & Cheese
Our take on the classic. Penne pasta and a blend of cheddar, American, Parmesan-Asiago, mozzarella blend and Alfredo sauce, oven baked to creamy, bubbly perfection.
Spicy Buffalo 5-Cheese Mac & Cheese
Our creamy, oven baked 5-cheese Mac & Cheese drizzled with buffalo sauce for a spicy kick.
Chicken Alfredo
Grilled chicken breast and creamy Alfredo sauce mixed with penne pasta and baked to perfection.
Oven-Baked Sandwiches
Philly Cheese Steak
Tender slices of steak, American and provolone cheeses, fresh onions, fresh green peppers and fresh mushrooms.
Chicken Bacon Ranch
Grilled chicken breast topped with smoked bacon, creamy ranch and provolone cheese.
Italian
Pepperoni and ham topped with banana peppers, fresh green peppers, fresh onions and provolone cheese.
Chicken Parm
Grilled chicken breast, tomato-basil marinara, Parmesan- Asiago and provolone cheeses.
Buffalo Chicken
Grilled chicken breast, ranch, fresh onions, hot buffalo sauce, provolone, cheddar and cheese made with 100% real mozzarella.
Salads
Classic Garden
A crisp and colorful combination of grape tomatoes, red onions, carrots, red cabbage, cheddar cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Chicken Caesar
The makings of a classic: roasted white meat chicken, Parmesan cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Ranch
A flavorful creamy dressing with touches of buttermilk and garlic.
Balsamic
A light dressing with a blend of balsamic vinegar, oil and garlic.
Caesar
A savory dressing with a combination of garlic, anchovy and subtle notes of cheese.
Desserts
Chocolate Lava Crunch Cakes
Oven-baked chocolate cakes, crunchy on the outside with molten chocolate fudge on the inside.
Domino's Marbled Cookie Brownie
An irresistibly warn and gooey blend of milk chocolate chunk cookie and fudge brownie. This sharable dessert is oven baked at the time of order and cut into 9 pieces.
Cinnamon Bread Bites
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Drinks
Coca Cola®
Available in 20 oz and 2-liter bottles
Diet Coke®
Available in 20 oz and 2-liter bottles
Sprite®
Available in 20 oz and 2-liter bottles
Fanta® Orange
Available in 20 oz and 2-liter bottles
Dasani® Water
Available in 20 oz bottles
Dip Cups
Slice Sauce Dipping Cup
Creamy and zesty with a hint of Parmesan.
Ranch
A creamy buttermilk ranch dressing with hints of garlic and onion.
Blue Cheese
A creamy dressing with bits of aged blue cheese.
Hot Buffalo
Domino's own spicy buffalo sauce.
Honey BBQ
A sweet and smoky BBQ sauce with bold flavor.
Marinara
A sweet tomato sauce blended with garlic, basil and oregano.
Garlic
A buttery garlic sauce.
Sweet Mango Habanero
A perfect blend of sweet and spicy in one sauce.
Sweet Icing
A thick sweet icing with a hint of vanilla.
Reviews
3.4
443 reviews
5 stars
202
4 stars
57
3 stars
34
2 stars
25
1 star
125
- RORebekah OsmanJun 1, 20265.0Great place to get pizza. The employees are great.
- ADAndi DeStefanoMay 11, 20261.0Tried to order dinner for my elderly grandparents for delivery and food was “delivered” at 8:30pm per the app, didn’t show up until 9:30pm. The restaurant is less than a mile from their home!!! Store phone continuously rings and rings with nothing but a recorded message or an AI bot to listen to. No wonder this place has only had one star reviews in the last year.
- BEBobby EdmondsMay 6, 20264.0good
- DKDan KmettApr 29, 20263.0Busy but didn't get waited on for 10 min after my order was ready. Others came in after me and were given their order before me. Like about 5 -6 customers. Also pizza toppings were not correct and missing items!
- AEAnissa EvansApr 21, 20261.0I just placed a delivery order and your driver Anthony did not deliver to my address! I called the location and of course you can’t reach out to them. I put clear instructions on how to get to my location and was not delivered to my door. I need my refund. This is unacceptable. I placed my order at 2:49 and it said it was delivered at 3:15. It was not!
Frequently Asked Questions About Domino's Pizza
What types of pizza crust options does Domino's Pizza in Florence offer?
Domino's Pizza in Florence offers New York Style, Handmade Pan, and Parmesan Stuffed Crust pizza options.
What are the opening hours for Domino's Pizza on weekdays?
From Monday to Thursday, Domino's Pizza is open from 10:00 AM to midnight, and on Friday from 10:00 AM to 1:00 AM.
Is Domino's Pizza in Florence open on weekends?
Yes, it is open on Saturday from 10:00 AM to 1:00 AM and on Sunday from 10:00 AM to midnight.
Does Domino's Pizza provide delivery and pick-up services?
Yes, Domino's offers delivery, curbside pickup, and no-contact delivery services.
Where is Domino's Pizza located in Florence, SC?
It is located at 3416 West Palmetto St, Florence, SC 29501, USA.
What payment methods are accepted at Domino's Pizza Florence?
They accept various payment options including Afterpay, American Express, Apple Pay, Bitcoin, Cash, Credit Cards such as Mastercard and Visa, PayPal, and more.
How can I order pizza for delivery from Domino's Pizza in Florence?
You can order delivery through their website at https://www.dominos.com/en/restaurants?type=Delivery&utm_campaign=LocalMapsOrderDelivery&utm_source=LocalListings&utm_medium=loclist.
Are there any clothing stores near Domino's Pizza in Florence?
Yes, Jaycie's Closet Boutique is a nearby women's clothing store and boutique where you can shop for apparel before or after grabbing pizza.
What nearby salons and beauty services are close to Domino's Pizza?
Nearby options include Desert Sun Tanning, Kutz Kurlz Hair Studio, Embrace Natural Hair Salon, You'Nique Images Styling Salon, Bert's Hair Design, and Pete's Barber Shop for various beauty and hair services.
Are there any entertainment or activity places near Domino's Pizza?
Yes, ShowBiz Studio Performing Arts Company, a dance school and amusement park, is nearby and could be a great spot to visit alongside your pizza trip.
Brand Certified Facts from Domino's Pizza
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Certified July 05, 2026Yext Knowledge Graph
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