CafeSalad ShopSandwich RestaurantBreakfast RestaurantSoup RestaurantTake Out RestaurantCoffee ShopBakeryRestaurant Delivery ServiceCatererPanera
Panera Bread Cape Girardeau welcomes guests to our café with warm hospitality and quality ingredients. We serve a variety of menu favorites for breakfast, lunch, and dinner—including fresh coffee, bakery items, salads, soups, and sandwiches—crafted to help you feel good about what you’re enjoying. Whether you’re dining in while enjoying complimentary Wi‑Fi, ordering online for Rapid Pick‑Up, enjoying delivery, or planning catering for a large group, Panera Bread Cape Girardeau is here to make your day a little better. Food as it should be.
Explore offerings from Panera Bread on 3219 William St in Cape Girardeau, with popular sandwiches, soups & mac, salads, and pastries & sweets available at this location.
Smoked, pulled chicken raised without antibiotics, smoked Gouda, fresh avocado and cilantro, zesty sweet Peppadew™ peppers and chipotle sauce on Black Pepper Focaccia.
Smoked, pulled chicken, fresh mozzarella, vine-ripened tomatoes, red onions, fresh basil, chipotle aioli, salt and pepper on our Black Pepper Focaccia.
Black Forest ham, soppressata, provolone, romaine, red onion, sliced pepperoncini peppers, garlic aioli, and Greek dressing on our toasted French Baguette.
Melty fresh mozzarella, vine-ripened tomatoes, chopped basil, crisp romaine & lettuce blend, sprinkled with salt and pepper, and balsamic vinaigrette and garlic aioli drizzle on our Ciabatta.
Oven-roasted turkey breast, applewood smoked bacon with aged white cheddar, crisp mixed greens, vine-ripened tomatoes, sprinkled with salt and pepper, and our Signature Bravo sauce drizzle on our Tomato Basil Miche.
Oven roasted turkey breast, aged white cheddar, crisp mixed greens, vine-ripened tomatoes, red onions, garlic aioli, salt and pepper on our Country Rustic Sourdough.
A rich chunky chili with beef, kidney beans, fire roasted tomatoes and green chili peppers, simmered in a broth flavored with a blend of chilis, and cilantro.
Tender pieces of white-meat chicken simmered in a rich, perfectly seasoned homestyle chicken bone broth with curly egg noodles, sliced carrots, celery and herbs.
Vine-ripened pear tomatoes pureed with fresh cream for a velvety smooth flavor accented by hints of red pepper and oregano and topped with black pepper and sea salt croutons.
Romaine and crisp mixed greens tossed in a sweet white balsamic vinaigrette, topped with grilled chicken, grape tomatoes, red onions, toasted pecan pieces, feta, and apple chips.
Romaine and crisp mixed greens tossed in Green Goddess dressing, topped with grilled chicken, grape tomatoes, and pickled red onions, fresh avocado, applewood smoked bacon and a hard-boiled egg.
Romaine tossed in ranch dressing, with grilled chicken and drizzled with chipotle aioli, topped with fresh avocado, grape tomatoes, roasted corn, fresh cilantro, and blue corn tortilla strips.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, grilled chicken, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine tossed in Greek dressing, topped with grilled chicken, grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine tossed in Greek dressing, topped with grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine and crisp mixed greens tossed in ranch dressing, topped with grape tomatoes, pickled red onions, applewood smoked bacon, feta, and a hard-boiled egg.
A salty, chocolaty, caramel confection big enough to share. A large cookie with semi-sweet chocolate, milk chocolate, caramel pieces, pretzels and then topped with flake salt.
Soft and smooth with hints of citrus, roasted nut and chocolate. A blend of Central and South American beans. Light bodied with a bright sweetness. Freshly ground in cafes.
Subtle nutty tones with wonderful coffee flavor. Serves 10. Brewed fresh, so please allow additional 15 min./tote to prepare your order. 120 fl oz per tote.
Rich, bold and full-bodied, balanced with a smoky accent and sweet chocolate notes. Harvested from Central and South America. Serves 10. 120 fl oz per tote.
Carefully roasted from Arabica beans and freshly brewed. Brewed fresh, so please allow additional 15 min./tote to prepare your order. Serves 10. 120 fl oz per tote.
Smoked, pulled chicken, scrambled egg, white cheddar, zesty sweet Peppadew peppers, fresh avocado and cilantro, salt and pepper, and chipotle aioli on Ciabatta.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
Explore offerings from Panera Bread on 3219 William St in Cape Girardeau, with popular we’re here to help when and where you need us. available at this location.
We deliver your Panera favorites right to your door with contactless delivery. Just tell us where to leave your meal in the “Delivery Instructions” box when placing your order.
Panera pizza is here! Unbox the new flatbread pizzas in three varieties: margherita, chipotle chicken & bacon, and cheese. Pick it up, have it delivered, or grab it through the drive through for lunch or dinner.
Brittney is our favorite, she always goes above and beyond to make sure we have the best experience.
SW
Sherice Ward
Sep 24, 2026
1.0
Just when I thought I love Panera I watched a manager handle a floor rug with gloves on an then went on to handle other job duties in the restaurant, and did not change his gloves not one time can you say disgusting!! At its finest I took a picture of the manager but I can't seem to get it to post!!
LL
letsgobulls24
Sep 23, 2026
4.0
After joining the Sip Club about a year ago, Panera has become a staple during my travels. I’ve been to 25 locations or so at this point. My food today was great, as always, order was ready quick; my only gripe is the cleanliness. I prefer a booth and the 5 or so unoccupied booths had significant trash and crumbs underneath to the point where I made my way back towards the front to a small table along the window. Not a huge deal, and obviously the people who left a mess at those spots are at fault, but just an observation. PS a “bowl” is not enough soup- would love to see a bigger size :)
SH
Sergio Hernandez
Sep 9, 2026
5.0
I ordered food and my card didn’t go through, and I had to cancel the order but Lily put it on the house and didn’t charge me! Big shoutout to Lily great customer service really appreciate it!!
TY
Trenton Young
Aug 30, 2026
2.0
Service was great, kind, professional lady.
The menu was deeply unhelpful.
"Chicken [Market Adjective] Bowl" doesnt tell me whats in the actual food. I want to know what im ordering before I order it and I am not going to sit there and ask a trillion questions about the food.
Then $15 for a rice bowl is crazy. Especially since they come not seasoned. I know it broadens your target audience but salt isn't a political issue. Salt the food!
The bread was really good though!
Overall, I wont be back and dont recommend. Unless you like mysterious bland foods.
Does Panera Bread at 3219 William St accept reservations?
No, Panera Bread at this location does not accept reservations.
What are the operating hours for Panera Bread Cape Girardeau?
Panera Bread Cape Girardeau is open daily from 6:00 AM to 9:00 PM.
Does Panera Bread offer delivery and drive-thru services?
Yes, Panera Bread offers delivery and has a drive-thru at this location.
Can you order Panera Bread items online for pickup or delivery?
Yes, you can order online using Rapid Pick-Up or for delivery through their official ordering website and app.
What types of meals does Panera Bread serve throughout the day?
Panera Bread serves breakfast, lunch, brunch, and dinner.
What types of specialty foods does Panera Bread offer?
Panera Bread specializes in You Pick Two, Power Menu, hand-tossed salads, freshly-baked artisan breads, specialty breads, flatbread sandwiches, soup in a breadbowl, and vegetarian broth bowls.
Is there a nearby shopping center close to Panera Bread where customers can visit?
Yes, Park West Centre, a shopping center, is nearby and a great place to visit before or after dining at Panera Bread.
Are there other food options near Panera Bread in Cape Girardeau?
Nearby eateries include Honey Baked Ham, Popeyes® Louisiana Kitchen, Cracker Barrel Old Country Store, Red Lobster, Burger King, Chili's Grill & Bar, Olive Garden, and Asian Yummy Buffet, offering a variety of dining choices.
What options are available nearby for customers wanting a beauty or spa service?
Belladona Salon & Spa provides hair and beauty salon services nearby Panera Bread, ideal for a relaxing visit before or after your meal.
Does Panera Bread Cape Girardeau offer Wi-Fi and casual dining atmosphere?
Yes, Panera Bread offers complimentary Wi-Fi in a casual and warm welcoming environment.
Brand Certified Facts from Panera Bread
This information is certified by Panera Bread and published from the brand's official system of record. Data is distributed through an enterprise-grade knowledge management platform. Learn more about our data sources
Certified September 27, 2026Yext Knowledge Graph
Address
Categories
Geo coordinates
Legal business name
Hours of operation
Phone number
Official website
Syndication Network
Approved business data is pushed to 100+ publishers, including: