Certified by Les Sisters' Southern Kitchen • Aug 16, 2026
MondayClosed
Tuesday12:00 PM - 7:30 PM
Wednesday12:00 PM - 7:30 PM
Thursday12:00 PM - 7:30 PM
Friday12:00 PM - 7:30 PM
Saturday12:00 PM - 7:30 PM
Sunday12:00 PM - 5:30 PM
Menu
1 menu · 89 items
Explore offerings from Les Sisters' Southern Kitchen on 20450 Nordhoff St in Winnetka, with popular munchies, cajun & creole, po' boy combos, and southern soul food available at this location.
Diced grilled chicken and sausage link served on a toasted French roll, topped with slaw, mustard, and our signature BBQ sauce, accompanied by a side and a beverage.
These warm, puff pastries feature a rich chocolate hazelnut filling, and powdered sugar topping. These New Orleans staple pastries are available Until sellout.
Reviews
4.6
327 reviews
5 stars
268
4 stars
26
3 stars3
2 stars
10
1 star
20
RS
robin smith
Aug 11, 2026
5.0
The catfish dinner is off the chain. We came in on a Tuesday, but I'm definitely coming back on fish Friday!! not only was it seasoned, but it was the best temperature you could imagine for your food , (I can't stand room temperature, food that's supposed to be hot) the macaroni and cheese was exceptional, not dry..but cheesy and the collard greens and fries perfect! I can't say enough about this place. I wish I lived closer to it but for you folks that are in the Los Angeles area looking for a restaurant don't look past this one!! You won't be sorry!!
TH
TV Head
Aug 11, 2026
5.0
Great place! As someone who grew up in the rural south, this is the food I’ve been missing! Great Po boys and jambalaya! The catfish made me feel like I was back at my grandparents house! Can’t recommend this place enough.
JG
Joney Gasbarro
Aug 5, 2026
4.0
This was the first time I've been to this location on Nordhoff Street. There were six or eight small bare tables against the walls with a couple chairs each. It was not very inviting. When the restaurant was located on Devonshire the room was full of tables with white tablecloths. It was a nice, casual setting. My order was for take out and, having been there, I know that I will always order their amazing food for take out.
TS
Tanya Shavelle
Aug 1, 2026
5.0
Always great food, fast and friendly service and warm and kind employees! An absolute joy every time!
JS
Janis Shea
Jul 31, 2026
5.0
Amazing food, owners know how to talk with their clients…just awesome!
Frequently Asked Questions About Les Sisters' Southern Kitchen
What are the regular business hours for Les Sisters' Southern Kitchen?
Les Sisters' Southern Kitchen is open from Tuesday to Saturday, 11:00 AM to 8:00 PM, and on Sunday from 11:00 AM to 6:00 PM. The restaurant is closed on Mondays.
Is Les Sisters' Southern Kitchen open on holidays?
Les Sisters' Southern Kitchen is closed on the holiday of November 2, 2025.
What are the takeout hours at Les Sisters' Southern Kitchen?
Takeout is available Tuesday through Saturday from 11:00 AM to 7:45 PM, and Sunday from 11:00 AM to 5:45 PM. The restaurant does not offer takeout on Mondays.
Does Les Sisters' Southern Kitchen offer delivery services?
The restaurant is located at 20450 Nordhoff St, Winnetka, CA 91311, USA.
What type of cuisine does Les Sisters' Southern Kitchen serve?
Les Sisters' Southern Kitchen serves Southern, Cajun, Creole, soul food, seafood, and offers brunch and Po’ boys among other Southern specialties.
Can I order food online from Les Sisters' Southern Kitchen?
Yes, you can view the menu and place orders online at https://lessisters.com/menu.
What nearby restaurants can I visit along with Les Sisters' Southern Kitchen?
Nearby restaurants include Sazon Colombia, a Colombian and Latin American restaurant, and Sandwich Man, a sandwich shop and delicatessen, which you might enjoy visiting before or after dining at Les Sisters'.
Are there beauty salons near Les Sisters' Southern Kitchen where I can get a haircut or spa treatment?
Yes, there are several nearby beauty salons including Shear Bliss, The Hair Editor, and Extensions Plus where you can enjoy salon and spa services before or after your meal.
What local services are near Les Sisters' Southern Kitchen that might be useful for visitors?
Nearby you can find various services such as Chatsworth Transmission for automotive needs, Valley Smiles dental and medical services, and myBekins for moving and storage, which visitors might find convenient.
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