Need a rental car in Cape Girardeau, MO? Enterprise Rent-A-Car is Here For It. Whether your car is in the shop, you're running errands, or planning a weekend getaway, we're ready with a wide range of vehicles and flexible rental options. Enjoy easy, stress-free rentals and friendly service that gets you on your way fast. Reserve your rental car with Enterprise at our Kingshighway location today.
Made a reservation for 12pm, im still sitting here at 1:30pm and still dont have a car yet. Seems like a plan ahead was a waste of time.
MS
Mostakin Sheikh
Aug 15, 2026
1.0
Very Disappointing Experience — Poor Communication
I had a very frustrating experience with Enterprise. Before going to the location, I specifically confirmed that I could rent the car using my debit card. Based on that information, I spent about one hour traveling to the location and also paid for an Uber to get there.
However, when I arrived, I was suddenly told that I needed a credit card and that my debit card could not be accepted under their requirements. Nobody clearly explained this to me before I made the trip.
I ended up wasting my time and money on Uber just to be told at the counter that I couldn’t rent the vehicle. If the requirements had been explained correctly over the phone, I could have avoided the entire trip and the extra transportation cost.
This was extremely disappointing and shows a serious lack of communication. Enterprise should make sure their employees provide accurate information before customers travel to the location. I would not recommend this location based on my experience.
TR
Troy Roberts
Aug 15, 2026
1.0
1. Charged me for insurance double the amount, Also charged my credit card 2 weeks later for a Toll. Why make a appointment if your car isn't ready? They aren't ready, need to clean, or go get. Parking lot is too small. I recommend go to AVIS/Budget down the road it cost 25 percent less and there was no wait.
DJ
Dustin Jarrell
Aug 4, 2026
5.0
I'm not going to lie. Things started out rough. The van was returned to them prior to my rental in less than ideal shape. The smell was horrible and we found out later that the oil fill cap was missing. The staff at Cape Girardeau Enterprise was amazing though. They immediately noticed and fixed the smell and when we had to purchase the fill cap they reimbursed us completely with an added discount for our trouble. We were completely satisfied with the rental and the service was outstanding. We will be renting again from the Cape Girardeau Enterprise for all of our rental car needs.
SR
Sheila Robinson
Aug 2, 2026
3.0
Van was nice. Service was not. Didn't pick me up at time we agreed on. I had to call several times to be picked up. I had reservations for 2 weeks ahead of time and still didn't have a vehicle ready when I got there. Very unprofessional.
Frequently Asked Questions About Enterprise Rent-A-Car
What types of vehicles can I rent at Enterprise Rent-A-Car in Cape Girardeau?
Enterprise offers a wide range of vehicles including standard cars, vans, and luxury car rentals to fit your needs.
Where is Enterprise Rent-A-Car located in Cape Girardeau?
Enterprise Rent-A-Car is located at 2008 N Kingshighway, Cape Girardeau, MO 63701.
What are the business hours for Enterprise Rent-A-Car at the Kingshighway location?
From Monday to Friday, the hours are 7:30 AM to 6:00 PM. On Saturdays, they are open from 9:00 AM to 12:00 PM, and on Sundays, from 10:00 AM to 1:00 PM.
Can I make a reservation online for a rental car at this location?
Yes, you can reserve your rental car online through Enterprise's website at http://enterprise.com/reserve.
What payment options does Enterprise Rent-A-Car accept?
Enterprise accepts American Express, Cash, Check, Discover, Mastercard, and Visa for payments.
Does Enterprise Rent-A-Car offer any special rental deals?
Yes, they offer great weekend rates which you can book through their weekend specials page.
Do they provide airport pick-up services at this Enterprise location?
Yes, Enterprise Rent-A-Car at Kingshighway offers airport pick-up services for your convenience.
What hotels are located near Enterprise Rent-A-Car in Cape Girardeau?
Nearby hotels include Quality Inn and Americas Best Value Inn Cape Girardeau, which are convenient options if you need accommodations during your rental period.
What local attractions or landmarks can I visit near the Enterprise Rent-A-Car location?
You can visit the Cape Girardeau landmark and historical buildings nearby, perfect for sightseeing before or after your rental car visit.
Are there nearby services related to automotive care close to Enterprise Rent-A-Car?
Yes, Synergy Performance for automotive repair and Cape Auto Spa or Club Car Wash for car washing and detailing are nearby.
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