Certified by Holiday Inn Express & Suites San Antonio NW-Medical Area by IHG • May 17, 2026
HotelWedding VenueBusiness Meeting LocationsHoliday Inn Express
Hotel near San Antonio Medical CenterLocated off Interstate 10 and in the heart of San Antonio, Texas, our hotel's convenient access to the airport and numerous attractions and corporations makes it the premier place to stay while visiting this cultural gateway to the Southwest.Because our San Antonio hotel's near the Alamo and Six Flags, guests are encouraged to spend a few days enjoying the thrills of both attractions. In addition, the entire family can enjoy a trip to the River Walk, just a few miles from our hotel. Browse the shops and restaurants that line this pedestrian area while you enjoy a scenic stroll along the river.
Our corporate travelers appreciate our San Antonio, Texas hotel's 24-hour Business Center that boasts such amenities as fax, copy, e-mail and print services. We are located just a few minutes from the South Texas Medical Center, Verizon, Toyota, Bank of America, Wachovia and the airport. Also, be sure to reserve our spacious meeting room, with accommodations for up to 25 guests.When compared to other San Antonio hotels near the Alamo and River Walk, our amenities surely stand out. We offer a relaxing outdoor pool in addition to our well-equipped Fitness Center to help you burn off those extra calories. And don't forget our free, Express Start breakfast bar with our signature cinnamon rolls and 100% Arabica bean coffee, which provides the perfect start to your day .
Location
Certified by Holiday Inn Express & Suites San Antonio NW-Medical Area by IHG • May 17, 2026
Holiday Inn Express & Suites San Antonio NW-Medical Area by IHG
Certified by Holiday Inn Express & Suites San Antonio NW-Medical Area by IHG • May 17, 2026
MondayOpen 24 hours
TuesdayOpen 24 hours
WednesdayOpen 24 hours
ThursdayOpen 24 hours
FridayOpen 24 hours
SaturdayOpen 24 hours
SundayOpen 24 hours
Reviews
3.2
325 reviews
5 stars
107
4 stars
58
3 stars
37
2 stars
27
1 star
96
KC
Karen Cleaves
6 days ago
4.0
Close to medical appointment.
MM
Marissa
May 12, 2026
1.0
Terrible hotel. Hard to believe this is a Holiday Inn. Dirtiest one I've ever been to. Housekeeping does not care and the higher ups don't either. Hallway was hot and muggy, carpet in room was covered in stains. The breakfast was very limited, no effort. I do not recommend this hotel. There are many more better options in San Antonio. Our mistake for booking here.
JL
Jose Lucio
Apr 29, 2026
1.0
The entire hotel and parking lot had issues. First the parking lot has many pot holes and concrete debris. Everywhere you look. Puddles of water which took up 4-6 parking spots. Room key’ed entry door from parking lot doesn’t work. 4th floor Ac wasn’t working. I notified long grey haired lady at the front desk and she said she would get someone to fix it. That never happened. I sent my room Ac to 60 to keep the hallway heat from warming up my room to much. Ice machine on the 4th floor has mold and rust everywhere. The only good thing was we only stayed for 1 night which was to many. Don’t bother with this place.
LC
lenin chowdary
Apr 10, 2026
1.0
This was one of the most disturbing hotel experiences I’ve ever had.
We checked in around 9:00 PM through Priceline, received our keys for Room 424, and everything seemed normal. But around 1:00 AM, someone tried to open our room door and started banging loudly. A few minutes later, another person came back knocking aggressively and asking for our ID and name from outside the door — without even properly identifying themselves.
We were understandably scared and called the front desk, only to be told by the night shift employee that they “couldn’t find our name in the system” and that the room was supposed to be empty. Instead of handling this calmly, he said he would come back again if he didn’t find our information — which made the situation even more uncomfortable.
To avoid further disturbance, I had to go down to the front desk in the middle of the night, where I was kept waiting for about 20 minutes while they struggled to locate my booking — even after I provided my ID and confirmation details. Eventually, they realized the issue came from poor communication between shifts and that they had mistakenly reassigned our room to another guest.
At no point did anyone apologize properly, show concern for our safety, or offer to involve a manager. Being woken up by strangers trying to enter your room at 1 AM is not just inconvenient — it’s frightening.
This experience showed a complete lack of professionalism, communication, and basic guest safety. I would strongly reconsider staying here.
JG
Juan Gonzalez
Apr 10, 2026
1.0
I’m extremely upset with how this was handled. I booked two rooms back in early March at Holiday Inn Express in San Antonio (102 Spencer Lane), and my reservation was canceled on the SAME DAY I was supposed to check in (April 10).
I received a cancellation notification with no real explanation and no prior warning, leaving me scrambling at the last minute to find another place to stay. This completely disrupted my plans and caused unnecessary stress.
When customers book weeks in advance, especially for multiple rooms, there should be some level of reliability and accountability. Canceling a confirmed reservation the day of check-in is completely unacceptable and shows a lack of professionalism.
At the very least, there should have been communication, options, or assistance in rebooking elsewhere. Instead, I was left on my own.
I would not trust this location with future reservations and would strongly caution others to have a backup plan if booking here.
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