Certified by Best Western Plus Santee Inn • Jun 21, 2026
HotelBest Western
At the Best Western Plus Santee Inn you’re sure to find that little something extra. With our modern amenities and thoughtful design, the Best Western Plus Santee Inn will stand out among other hotels in Santee,SC. For the business traveler, a spacious work desk and free internet access are included in all our guest rooms to ensure you don’t miss a beat while you’re away from the office. For extended stays, each room provides a convenient in-room mini fridge that is ideal for drinks and snacks. We also have an in-house fitness room, so you can keep up your workout routine while you’re on the road. As always, the Best Western Plus Santee Inn will provide you with the superior customer service that you are used to at Best Western® Hotels & Resorts.
Location
Certified by Best Western Plus Santee Inn • Jun 21, 2026
Certified by Best Western Plus Santee Inn • Jun 21, 2026
MondayOpen 24 Hours
TuesdayOpen 24 Hours
WednesdayOpen 24 Hours
ThursdayOpen 24 Hours
FridayOpen 24 Hours
SaturdayOpen 24 Hours
SundayOpen 24 Hours
Reviews
4.3
1,663 reviews
5 stars
979
4 stars
424
3 stars
147
2 stars
44
1 star
69
BE
Bob Engert
5 days ago
5.0
This hotel welcomes you with Southern charm. Beautifully furnished and decorated, it is convenient to I-95 and local restaurants. We were given a clean quiet room near the back of the property, for guests with limited mobility. The large bathroom had the walk-in shower we requested for my 97 year old Mom. We enjoyed a restful night with no road or guest noise. Jennifer was particularly helpful in arranging our stay. The included breakfast buffet is outstanding. The lady attending was friendly and helpful to us and all the guests. I'm sorry I didn't get her name to share. The food selection has something for everyone, young and old, and you will leave full and satisfied. We will look forward to staying again someday. Thanks for making our visit a pleasant one.
DL
Denise Leonard
Jun 14, 2026
5.0
Very pleased with room & pet area. Good eats close buy. Easy on and off 95. Will stay again.
BC
Buffy Chix
Jun 2, 2026
5.0
Right off I-95, so convenient. Dog friendly rooms. Spotless and so clean. No pet orders.
Great grassy area across parking lot from our room to walk our pup.
Had an excellent meal at the Captains restaurant right next door. Fantastic.
Great place to stay! Happy upbeat staff. You can’t go wrong staying here!
VW
Vicki Wood
May 30, 2026
5.0
What an adorable and beautifully decorated Best Western! Drive up rooms and a beautiful pool with towels provided. A very old Bible opened to Ephesians 2 and complimentary cookies available as well as a little snack store in the lobby. Rooms clean and comfortable. Breakfast in the morning was plentiful and delicious! Felt like home’
JR
Jim Rossick
May 29, 2026
3.0
Only reason i give this a 3 is cause of the great front desk ladies, the lady making the breakfast, the breakfast itself and the location close to the highway..room was disappointing to say the least. Def not worth an 8.8 on Hotels website
Frequently Asked Questions About Best Western Plus Santee Inn
What is the address of Best Western Plus Santee Inn?
The Best Western Plus Santee Inn is located at 9059 Old Number Six Hwy, Santee, SC 29142, USA.
Does Best Western Plus Santee Inn offer free WiFi?
Yes, free internet access is available in all guest rooms at Best Western Plus Santee Inn.
Is there a fitness center available at Best Western Plus Santee Inn?
Yes, the hotel features an in-house fitness room for guests to use during their stay.
What amenities are included in guest rooms at Best Western Plus Santee Inn?
Guest rooms include a spacious work desk, free internet access, and a mini fridge ideal for drinks and snacks during extended stays.
Are there dining options within Best Western Plus Santee Inn?
Yes, the hotel has an on-site restaurant providing dining options for guests.
What are the operating hours of Best Western Plus Santee Inn?
The hotel operates 24 hours a day, 7 days a week, providing service around the clock.
How can I contact Best Western Plus Santee Inn for reservations or inquiries?
You can call the hotel at +1 803-854-3089 or visit their official website at http://bestwestern.com.
What nearby restaurants can I visit when staying at Best Western Plus Santee Inn?
Captain's Quarters Seafood and Steak and Huddle House are nearby popular dining options offering American and seafood cuisine.
Are there any local attractions near Best Western Plus Santee Inn worth visiting?
While the profile mainly lists nearby restaurants, guests can explore local dining at Captain's Quarters Seafood and Steak and Huddle House within close proximity.
How can nearby restaurants enhance my stay at Best Western Plus Santee Inn?
Guests can conveniently enjoy a variety of dining experiences at nearby restaurants like Captain's Quarters Seafood and Steak and Huddle House without traveling far from the hotel.
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