Certified by Holiday Inn St Louis SW - Route 66 by IHG • Jun 28, 2026
HotelWedding VenueBusiness Meeting LocationsConference CenterHoliday Inn
Experience the charm of St. Louis at the renovated Holiday Inn St Louis SW - Route 66, a hotel blending utmost comfort with a prime location and exceptional service to provide an unforgettable stay.
Located on historic Route 66 at highways I-44 and I-270, just 20 minutes from St. Louis Lambert International Airport, we offer easy access to top St. Louis attractions like the Gateway Arch, Missouri Botanical Garden, and the St. Louis Zoo. Catch a St. Louis Cardinals game at Busch Stadium, and visit the Magic House, St. Louis Science Center, Six Flags, or World Wide Technology Soccer Park. Business travelers appreciate proximity to companies like Maritz and Harris-Stowe and top medical centers like Barnes-Jewish Hospital, St. Louis Children's Hospital, SSM Health, and Mercy Hospital.
Enjoy top amenities like a resort-style outdoor pool with luxury cabanas and a state-of-the-art Fitness Center. Relax by our fire pit with a cocktail or play yard games with family or friends. Savor delicious dining at our award-winning steakhouse, Twisted Tree Steakhouse, plus breakfast at Wakey Wakey Breakfast Place and cocktails at Luxe Libations: The Lounge by Twisted Tree. From our elegant Sunset Event Center venues to complimentary parking, free Wi-Fi, and spacious rooms and suites, we are the ideal choice for an exciting and enjoyable stay in St. Louis.
Location
Certified by Holiday Inn St Louis SW - Route 66 by IHG • Jun 28, 2026
Certified by Holiday Inn St Louis SW - Route 66 by IHG • Jun 28, 2026
MondayOpen 24 Hours
TuesdayOpen 24 Hours
WednesdayOpen 24 Hours
ThursdayOpen 24 Hours
FridayOpen 24 Hours
SaturdayOpen 24 Hours
SundayOpen 24 Hours
Products & Services
1 list · 2 items
Explore offerings from Holiday Inn St Louis SW - Route 66 by IHG on 10709 Watson Road in St. Louis, with popular holiday inn services available at this location.
Holiday Inn Services
2 items
Holiday Inn Services
Kids Eat Free
Up to two children may eat for free for each accompanied adult ordering an entrée from the regular menu. Please see website for additional terms and conditions.
Complimentary High-Speed Wi-Fi
Holiday Inn provides complimentary high-speed Wi-Fi access to all our guests throughout the hotel premises.
Reviews
4.0
1,481 reviews
5 stars
676
4 stars
406
3 stars
198
2 stars
82
1 star
119
SS
Steven
1 day ago
1.0
TERRIBLE PLACE TO STAY. BUGS, POTENTIALLY BED BUGS.
We stayed at this Holiday Inn last night and we couldn't have had a worse experience. Out of all of the hotels we've ever stayed at, this is the worst, ever. The front desk service was rude and unwelcoming from the moment we arrived. Because of the World Cup, the hotel was incredibly loud, with guests screaming throughout the night, making it nearly impossible to relax or sleep. The patrons were drunk and didn't go to bed until 3am. We complained over text and the hotel said it was out of their scope of service.
The walls were also extremely thin, so you could hear almost everything happening in neighboring rooms and the hallways. There was a huge stain on the chair in our room, which made the cleanliness of the hotel feel questionable. On top of that, the elevators smelled strongly of smoke, and one of the elevators was broken during our stay, causing long waits. There were lots of rowdy guests running the hallways of the hotel 24/7.
The room was fine at first. The bathroom especially the shower needed a good scrub (it was black with filth) but the bed was comfortable. However, we woke up to a bug crawling on us and a couple of them on the bed! We were sure it was a bed bug, but after further research it could have been a carpet beetle due to the spotted pattern. We still aren't fully sure but there must have been an infestation in the mattress.
When telling the front desk staff; they noted that they do not offer refunds for bed bugs/carpet beetles. They said they could have a third party exterminator come out and inspect; and if a bed bug ingestion was found they would call back an offer a PARTIAL refund.
Overall, this was a very disappointing experience, and I expected much better from a Holiday Inn. We will NEVER return, and now have to wash all of our clothing incase those were BED BUGS.
WS
W Sponaugle
2 days ago
2.0
Fire alarms randomly going off. Possible bedbug exposure. Staff that were not very helpful when I went to complain. Adding a second star for Twisted Tree. Location is good.
JM
Josh Mulkey
4 days ago
5.0
This was a great hotel. The property and rooms are nice and very well kept. The staff is extremely friendly and helpful. There’s a restaurant on site with amazing food and an extensive menu.
KS
Karina Smith
5 days ago
5.0
We had an excellent 3 night stay here (two adults and two kids). The rooms are beautiful and comfortable, the pool and outdoor fire tables were fabulous, and every interaction we had with staff was great! Plenty of towels and bedding in our room, and it was a big bonus that liquid hand soap is one of the toiletries. Honestly, that alone thrilled me, making everything else felt like a bonus (if you’ve had to use hotel bar soap with kids, you get it).
I highly recommend staying here, and we will absolutely stay here again on future trips to St. Louis. In fact, I would even go so far as to say the hotel helped us decide that we would indeed be visiting again.
One last note: we did upgrade our stay to include breakfast, which was good, but not something we would add next time. The restaurant is physically connected to the hotel, but is a separate establishment. Menu options were limited and service was so-so, but as it’s separate, I’m not dinging any stars from the hotel itself—I only mention it for anyone on the fence about the upgrade.
MM
maddie maragnu
Jun 21, 2026
3.0
Stay was great other than the fact that house keeping tried entering the room without knocking or anything. Luckily we had the lock on. Checkout was not until 11 and this happened well before then.
Frequently Asked Questions About Holiday Inn St Louis SW - Route 66 by IHG
Are there business-friendly amenities at Holiday Inn St Louis SW – Route 66?
Yes, Holiday Inn St Louis SW – Route 66 includes a 24-hour Business Center with computers, printers, fax services, and shipping options—ideal for business travelers and remote work needs.
Is the hotel pet-friendly?
Yes, the hotel is pet-friendly, welcoming your furry friends with comfortable accommodations. There are designated pet-friendly rooms and nearby parks for easy walks.
What are the dining options at the hotel?
Guests can dine at our on-site restaurant, which offers a variety of American dishes throughout the day. There's also a bar for evening drinks and snacks. Room service is available for those who prefer to dine in the comfort of their room.
Does the hotel have event spaces?
Yes, the hotel offers versatile event spaces, including meeting rooms equipped with modern audiovisual technology. These spaces are ideal for corporate meetings, conferences, weddings, and other social gatherings. Our dedicated event planning team is on hand to assist with every detail.
Is there free parking available?
Absolutely. The hotel provides complimentary on-site parking for all guests, with ample space for cars, SUVs, and even larger vehicles like RVs and buses. This convenience makes it easy for guests to explore the St. Louis area without worrying about parking fees or availability.
Does Holiday Inn St Louis SW – Route 66 offer meeting/event spaces beyond banquet halls?
Yes, Holiday Inn St Louis SW – Route 66 provides over 15,500 sq ft of flexible event space, including the Sunset Ballroom and seven breakout rooms equipped with A/V tech, ideal for corporate events or social functions.
Can guests at Holiday Inn St Louis SW – Route 66 enjoy a firepit or outdoor lounge area?
Yes, Holiday Inn St Louis SW – Route 66 features a cozy outdoor firepit lounge area right off the outdoor pool, perfect for relaxing evenings or casual socializing.
Are the rooms at Holiday Inn St Louis SW – Route 66 equipped with mini-fridges and microwaves?
Yes, all guest rooms at Holiday Inn St Louis SW – Route 66 feature a mini fridge and microwave to ensure guests have convenient in-room dining options.
Does Holiday Inn St Louis SW – Route 66 provide dry-cleaning and laundry services?
Yes, guests at Holiday Inn St Louis SW – Route 66 have access to on-site self-service laundry facilities and dry cleaning/laundry valet options for added convenience.
What are the check-in and check-out times at Holiday Inn St Louis SW – Route 66?
Check-in time is at 3:00 PM and check-out time is at 11:00 AM at Holiday Inn St Louis SW – Route 66.
Does the hotel accommodate guests with pets?
Yes, Holiday Inn St Louis SW – Route 66 is pet-friendly and welcomes both cats and dogs.
Are there fitness facilities available for guests?
Yes, the hotel offers a fitness center with free access including free weights and a treadmill.
Is there parking available for guests, and is it free?
Yes, the hotel provides free self-parking with accessible parking spaces available.
Does Holiday Inn St Louis SW – Route 66 provide business and event amenities?
Yes, the hotel features a 24-hour business center, seven meeting rooms, over 15,500 sq ft of flexible event space including the Sunset Ballroom, and a dedicated event planning team.
What dining options are available at the hotel?
Guests can enjoy two on-site restaurants including the award-winning Twisted Tree Steakhouse, the Wakey Wakey Breakfast Place for breakfast, and Luxe Libations bar for cocktails and snacks. Room service is also available.
Are there any nearby car rental agencies that guests can use?
Yes, guests can conveniently find Budget Car Rental and Avis Car Rental near the hotel, making it easy to explore St. Louis by car.
What nearby family-friendly attractions can guests visit?
Guests can visit nearby attractions such as the St. Louis Zoo, Missouri Botanical Garden, Magic House, St. Louis Science Center, and Six Flags, all within easy reach from the hotel.
How can guests use nearby dining options around the hotel?
Besides the hotel’s own dining, guests can explore nearby restaurants like Steak 'n Shake for casual dining, Lion's Choice for fast American food, Wingstop for chicken wings, and Yogurtland for desserts, enriching their local food experience.
Is there free Wi-Fi available at Holiday Inn St Louis SW – Route 66?
Yes, free Wi-Fi is available throughout the hotel's public areas for all guests to stay connected.
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