Brand Certified
Holiday Inn Express & Suites Cape Girardeau I-55 by IHG
4.6(835 reviews)
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • Aug 16, 2026
Business Details
3253 William Street, Cape Girardeau, MO
63701, United States
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • Aug 16, 2026
(573) 334-4491
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • Aug 16, 2026
https://www.ihg.com/redirect?path=hd&localeCode=en&brandCode=EX®ionCode=US&hotelCode=CGIWS
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • Aug 16, 2026
About
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • Aug 16, 2026
HotelWedding VenueBusiness Meeting LocationsHoliday Inn Express
Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!
Location
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • Aug 16, 2026
Holiday Inn Express & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
63701, United States
Hours
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • Aug 16, 2026
MondayOpen 24 Hours
TuesdayOpen 24 Hours
WednesdayOpen 24 Hours
ThursdayOpen 24 Hours
FridayOpen 24 Hours
SaturdayOpen 24 Hours
SundayOpen 24 Hours
Reviews
4.6
835 reviews
5 stars
624
4 stars
137
3 stars
33
2 stars
14
1 star
27
- TCTonia CohoonJul 26, 20265.0Extremely clean. It's hard to find any establishment these days that is clean. Front desk workers very helpful, and nice. Only complaint is the intense chlorine smell of the pool area, but I have found this with other places. No ventilation. I will definitely stay again.
- LHLacy HoffmanJul 15, 20265.0Great hotel for an even better price. The king suite was very spacious and clean. Had a pull out sofa and desk as well. The shower was great with dove shampoo/conditioner/soap on the wall. The hotel breakfast was wonderful. They had a hot breakfast with lots of variety. They had sausage, omelets, biscuits and gravy, waffle maker, oatmeal, muffins, cinnamon rolls, Yogurt, cereal etc. They had a pool, but I did not see a hot tub. Very safe area. Would 100% stay here again! 10/10
- RSRoy SrJul 15, 20265.0Remember if your having procedures at ST. FRANCIS HOSPITAL, let them know. Discount on room.
- JWJohn WallaceJul 15, 20261.0I drove by did not stop
- AWAnne WilliamsonJun 27, 20265.0Here’s an updated version with those details included: One of the highlights of our trip was staying at the Holiday Inn Express & Suites Cape Girardeau I-55. As someone with a mobility disability, I was especially impressed by the accessibility of the suite. The roll-in shower was one of the best-designed hotel showers I’ve ever used. It was spacious, easy to access, and thoughtfully laid out for safety and independence. The suite itself was large, open, and exceptionally functional, with plenty of room to maneuver a wheelchair or walker. The furniture placement and overall layout created a comfortable, uncluttered space that made getting around much easier than in most hotel rooms. The complimentary breakfast was very good, with a nice variety of options, and the automatic coffee machines were a great touch. They made it easy to enjoy a fresh cup of coffee just the way you like it. Another feature we appreciated was the hotel’s multiple entrances, which made it easy to park near our room and avoid a long walk through the building. This hotel clearly put thought into both accessibility and guest comfort. I would gladly stay here again and highly recommend it, especially for travelers who need an accessible room.
Frequently Asked Questions About Holiday Inn Express & Suites Cape Girardeau I-55 by IHG
What are the check-in and check-out times at Holiday Inn Express & Suites Cape Girardeau I-55?
Check-in time is at 3:00 PM and check-out time is at 11:00 AM.
Is breakfast included during my stay at this hotel?
Yes, a free buffet breakfast is available for all guests.
Does the hotel offer free Wi-Fi?
Yes, free Wi-Fi is available in public areas throughout the hotel.
Are there fitness facilities available at the hotel?
Yes, the hotel has a fitness center with elliptical machines, free weights, and treadmills available for free use.
Is parking available at the Holiday Inn Express & Suites Cape Girardeau I-55?
Yes, free parking is available for all guests.
Does the hotel provide accommodations accessible for guests with mobility challenges?
Yes, the hotel is mobility accessible and offers accessible parking and an elevator.
Are pets allowed at the hotel?
No, pets including cats and dogs are not allowed on the property.
What nearby attractions can I visit while staying at the Holiday Inn Express & Suites Cape Girardeau I-55?
Guests can visit Southeast Missouri State University to enjoy sports events, explore the Old Downtown area for shops and restaurants along the Mississippi River, and spend time outdoors at Trail of Tears State Park with activities such as hiking, biking, and fishing.
Are there any nearby dining options around the hotel?
Yes, nearby dining options include Olive Garden for Italian cuisine, Popeyes® Louisiana Kitchen for fast food, Panera Bread for coffee and bakery items, Red Lobster for seafood, and Cracker Barrel Old Country Store for American and barbecue dishes.
Can I hold business meetings or events at the Holiday Inn Express & Suites Cape Girardeau I-55?
Yes, the hotel has two spacious meeting rooms equipped with audio/visual equipment, suitable for business functions and special events.
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