Certified by Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG • Aug 16, 2026
HotelWedding VenueBusiness Meeting LocationsHoliday Inn Express
Whether you're coming to Jacksonville for a visit to the Mayo Clinic or simply to enjoy the beach, the Holiday Inn Express & Suites Jacksonville SE – Med Center is your home away from home. Conveniently located just off Highway 202, J Turner Butler Blvd., our smoke-free hotel is only three miles from the Mayo Clinic campus. Relax in our spacious guest rooms, designed with your comfort and productivity in mind. Enjoy complimentary wifi, and unwind with a large-screen HDTV.
The hotel is situated near major companies, including Allstate Insurance, Landstar, JP Morgan Chase, Windsor Parke Golf Course, and the University of North Florida (UNF).
We are also just minutes from St. John’s Town Center—Jacksonville’s premier destination for upscale shopping and dining—as well as the beaches and Ponte Vedra, home to TPC Sawgrass and the annual PGA Tour Players Championship. For golf enthusiasts, you'll appreciate our unique location right on the 15th hole of Windsor Parke Golf Course.
We offer a complimentary weekday shuttle to Mayo Clinic available Monday-Friday.
If you're hosting an event, take advantage of our 1,250-square-foot meeting space. Stay active in our 24-hour fitness center or unwind in our partially covered outdoor pool featuring relaxing water elements. For dining options, you won’t have to go far—Ruby Tuesday, Publix, and Tropical Smoothie Café are just a few options within walking distance.
Location
Certified by Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG • Aug 16, 2026
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Certified by Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG • Aug 16, 2026
MondayOpen 24 Hours
TuesdayOpen 24 Hours
WednesdayOpen 24 Hours
ThursdayOpen 24 Hours
FridayOpen 24 Hours
SaturdayOpen 24 Hours
SundayOpen 24 Hours
Reviews
4.1
979 reviews
5 stars
526
4 stars
223
3 stars
88
2 stars
58
1 star
84
MW
Mark’s Wife
3 days ago
5.0
This was the best hotel experience I believe we’ve ever had. From the front desk helping me over the phone, the front desk check in. The grab n go gift. The room was spotless and a great size. They texted us several times to make sure we didn’t need anything and it’s not far from the Mayo Clinic. Ten stars!!!
BH
Bradley Halker
Aug 12, 2026
1.0
Im writing this review to hopefully let everyone know that while I enjoyed staying at the holiday in express I was booking a hotel for us at the Mayo Clinic i went thru Expedia to book the room. While im not computer savvy i do no wrong from right and the lady i talked to Katherine bunszell quoted me a price of 374.58 for 2 nights at the holiday in express Jacksonville by Mayo Clinic i thought was a little expensive but I was ok for 2 nights. She went to book the room and said someone else had already booked it. So she went back in and said there was one room left but it would be 420 for 2 nights and it was the last one. So I booked the room. She did offer a cancellation policy for 40$ per night. I just hope holiday inn express does not endorse this kind of business.
KM
Kailey McCarty
Aug 4, 2026
5.0
We stayed in June due to a family member admitted to the Mayo Clinic. During a hard time, Kolandra working the front desk was such a blessing. She went above and beyond to help us extend our stay as needed each day and prevented us from having to change rooms.
JC
Jo Crossgrove
Aug 2, 2026
5.0
Nice clean hotel. Good, hot breakfast. Staff is always friendly and helpful.
The last time we stayed, we took advantage of the online check in. We only had to show my license to get our room keys. That can be very helpful when you have a busy schedule.
The neighborhood is fine. We've stayed here a few times so we know where it is located. We thought we were lost the first time. Follow the GPS to Publix and the hotel is off behind the right side of the Publix parking lot.
We will definitely stay here again.
KS
Keyla Smith
Jul 26, 2026
4.0
I came to Florida for vacation. I chose to stay in this hotel. I had a wonderful time. Definitely recommend for anybody that's looking for a nice area.
Frequently Asked Questions About Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
What are the check-in and check-out times at Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG?
Check-in is at 3:00 PM and check-out is at 11:00 AM.
Is breakfast included with a stay at this hotel?
Yes, a complimentary buffet breakfast is available for free to guests.
Does the hotel offer free Wi-Fi to guests?
Yes, free Wi-Fi is available in public areas throughout the hotel.
What fitness facilities are available at the hotel?
The hotel has a free 24-hour fitness center equipped with elliptical machines, treadmills, and free weights.
Are pets allowed at Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area?
Yes, pets are welcome at this hotel.
Is the hotel accessible for guests with mobility challenges?
Yes, the property is mobility accessible and includes accessible parking and an elevator.
Does the hotel offer a shuttle service to local attractions?
Yes, there is a complimentary weekday shuttle to the Mayo Clinic available Monday through Friday.
What nearby shopping and dining options are available to guests?
Guests can easily visit St. John’s Town Center for upscale shopping and dining, or walk to nearby places like Ruby Tuesday, Publix Super Market, and Tropical Smoothie Cafe.
Are there any recreational activities near the hotel?
Yes, the hotel is located on the 15th hole of Windsor Parke Golf Course, close to beaches and Ponte Vedra, which hosts the TPC Sawgrass golf tournament.
Can guests host meetings or events at the hotel?
Yes, the hotel offers 1,250 square feet of meeting space with three meeting rooms suitable for events and business meetings.
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