Certified by Holiday Inn Express & Suites San Diego Otay Mesa by IHG • May 17, 2026
HotelWedding VenueBusiness Meeting LocationsHoliday Inn Express
The newly renovated Holiday Inn Express & Suites San Diego Otay Mesa welcomes you! This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from Downtown San Diego and less than 1 mile from beautiful Tijuana, Mexico. We offer a convenient suburban location near the Cross Border Xpress, North Island Credit Union Amphitheatre, SeaWorld Aquatica, SeaWorld, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Learn about local history at the Cabrillo National Monument, the Air and Space Museum and the Maritime Museum, or visit us for fun annual events such as Comic Con. Check out Las Americas Premium Outlets with 125 outlet stores and 13 restaurants in a lovely outdoor setting, or try the Otay Town Center Mall, just four miles from our hotel. Business travelers will enjoy a stay at our San Diego hotel because of its convenient location near companies such as Toyota, Bose, Panasonic, Maxwell, Tyco, JVC, Siemens Medical and Samsung, each within six miles of our hotel in the Otay Mesa Industrial Park. The International Commercial Border Crossing is .25 miles away. The Brown Field Municipal Airport is three miles away. During your stay, enjoy a free hot breakfast, Fitness Center and outdoor pool. Check out our San Diego hotel room deals to start planning your trip today.
Location
Certified by Holiday Inn Express & Suites San Diego Otay Mesa by IHG • May 17, 2026
Holiday Inn Express & Suites San Diego Otay Mesa by IHG
Certified by Holiday Inn Express & Suites San Diego Otay Mesa by IHG • May 17, 2026
MondayOpen 24 hours
TuesdayOpen 24 hours
WednesdayOpen 24 hours
ThursdayOpen 24 hours
FridayOpen 24 hours
SaturdayOpen 24 hours
SundayOpen 24 hours
Reviews
4.0
1,040 reviews
5 stars
533
4 stars
246
3 stars
115
2 stars
52
1 star
94
JB
Jesus Bastida
May 11, 2026
4.0
La verdad si fuera possible el acceso al hotel es un poco difícil encontrar la entrada!!!
DS
Denise Spencer
May 7, 2026
5.0
I am writing to share my positive experience during my recent stay at your San Diego location. As a frequent guest of Holiday Inn Express, I have come to expect comfortable and clean accommodations, but the service I received during this visit was truly exceptional.
I want to specifically recognize manager Ramona for her outstanding assistance. She handled a complicated issue with my reservation with a warm smile and a professional attitude. As someone visiting from out of town and unfamiliar with the area, her kindness and helpfulness immediately put my mind at ease.
Ramona’s hospitality made a significant difference in my trip, and I wanted to ensure her efforts were acknowledged.
DD
Daisy
May 6, 2026
1.0
If I could give this place 0 stars I would. I stayed on Thursday to fly out of TJ Friday morning. Room was big enough however, the next morning I woke up with small bite marks on my thigh. I thought it was a mosquito bite or small spider. Then the itching and spots because gradually worse. Please do not stay here. THEY HAVE BED BUGS!!!!!
RR
Rebecca Rivera
Apr 28, 2026
3.0
The location is convenient and the staff were friendly, which made checking in a breeze. The room was comfortable, but it could have used some updating as it felt a bit worn. Overall, a decent stay, but there's definitely room for improvement.
BL
Betty Lynn
Apr 24, 2026
5.0
I had a wonderful stay at this hotel! From the moment I arrived, the staff was warm, welcoming, and attentive. Check-in was smooth and the price was very reasonable, which set the tone for the rest of my visit. Breakfast was great…Would recommend!
Frequently Asked Questions About Holiday Inn Express & Suites San Diego Otay Mesa by IHG
What are the check-in and check-out times at Holiday Inn Express & Suites San Diego Otay Mesa?
Check-in time is at 3:00 PM and check-out time is at 11:00 AM.
Does the hotel offer free breakfast?
Yes, the hotel provides a free buffet breakfast to all guests.
Is parking available and accessible at the hotel?
Yes, free accessible parking is available for guests at the hotel.
Are pets allowed at the Holiday Inn Express & Suites San Diego Otay Mesa?
No, pets including cats and dogs are not allowed at the property.
What fitness facilities are available to guests?
Guests can use the hotel's free fitness center which includes an elliptical machine, free weights, and a treadmill.
Is there a business center or meeting rooms available at the hotel?
Yes, the hotel has a business center and one meeting room available for guest use.
Does the hotel offer laundry services?
Yes, self-service laundry facilities are available at the hotel.
Are there any nearby shopping centers close to the hotel?
Yes, Las Americas Premium Outlets and Otay Town Center Mall are nearby, offering numerous stores and restaurants for guests to explore.
How can guests visit the famous San Diego Zoo or SeaWorld from the hotel?
The hotel is a short drive from attractions like the San Diego Zoo and SeaWorld, making it convenient for guests to enjoy these popular destinations.
Is there local transportation available to nearby attractions?
Yes, the hotel offers a local shuttle service which can help guests travel to nearby attractions and points of interest such as the Cross Border Xpress and North Island Credit Union Amphitheatre.
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