Our pet-friendly hotel is ideally located at the intersection of Highway I-85 & Cole Mill Rd. We’re just two miles from Duke University and Duke Medical Center, and six miles from North Carolina Central University. Downtown Durham attractions such as Durham Performing Arts Center (DPAC), Durham Bulls Athletic Park, restaurants, and bars are a short five-minute drive away. Enjoy free breakfast, WiFi, and a five-mile radius shuttle during your stay, as well as access to our fitness center, laundry facilities and indoor heated pool.
Location
Home2 Suites by Hilton Durham University Medical Center
Numerous reviews highlighted the exceptional service provided by staff members, particularly Priscilla and Terry, who were frequently mentioned for their friendliness and helpfulness.
Cleanliness
Guests consistently praised the hotel for its cleanliness, noting that the rooms and facilities were well-maintained and inviting.
Amenities
The hotel offers a variety of amenities, including a well-stocked breakfast, a hot chocolate station, and a comfortable lounge area, which were appreciated by many guests.
Comfort and Convenience
Many customers found the rooms comfortable and well-equipped, with convenient access to local attractions, especially Duke Hospital.
JE
Joanne Esterline
Jan 4, 2026
5.0
Staff was fabulous, room was immaculate as was entirety of hotel. The location is very good, parking more than ample. We travel here frequently and this will DEFINITELY be our must stay hotel whenever we return. Best stay at a Hampton property in a very long time!
CP
Chasta Posey
Jan 2, 2026
5.0
Ms. Gwen Tucker (the shuttle driver) is an angel on earth. She’s so sweet & her personality is so warm & inviting. She was pleasant & ensured my safety during the drive. She’s definitely a great asset to the Home2 family.
IP
isaac paida
Jan 1, 2026
5.0
Very nice hotel with helpful and friendly staff. Only about 6 minutes away from Duke University Hospital, and they have a free shuttle to anywhere within 5 mile radius. The shuttle driver, Gwen, is very helpful and friendly, I enjoyed chatting with her each time she gave me a ride.
JC
Justin Cruz
Dec 29, 2025
5.0
If this Hilton isn’t the premier Hilton in the chain of hotels, then Hilton is doing itself a disservice. The service here? Unparalleled by any other hotel chain, the breakfast situation? You get Gluten Free bread, multiple breakfast options, and the buffet is clean and well kept. If you’re somebody like me, I love a good gym at an hotel, and this gym?Amazing and high quality, which is a common theme here with the housekeeping both in the lobby and during room service being beyond words. I’ve never felt so accommodated and assisted by any hotel before this. Let me begin with Nick, who assisted me during the check in process (as well as Ms. Priscilla) who helped get me situated after a 8 hour ride into town. After that? I met with the manager of housekeeping who proceeded to have my room stocked with additional towels and housekeeping while we have been here.
I made a mention of my son’s birthday to the front desk staff when I arrived, and unbeknownst to me, my son received a beautiful cake, with a happy birthday card! I’m not sure if The GM Jonathan Sweet is the reason behind the great staff, but if he isn’t, I’ll still give him his flowers. As a New Yorker traveling with his family (two children) this Hilton is exceptional, and worth more than they charge (don’t shoot the messenger)
Words cannot do justice, and thank you’s can become monotonous, but hospitality like Hilton’s Home2Suites Durham University? They’re a real diamond in the industry, and I’ll say from my family to them, thank you guys.
RC
Rosita C
Dec 27, 2025
5.0
This hotel is fantastic! Excellent location off 85 for starts. Front desk was very friendly and accommodating. Super clean room. Very quiet. Had a great night's sleep! I've stayed in 4 other home 2 suites over the past year and this one is definitely the best! I highly recommend and if I pass through the area again, I'll definitely be back!