We are at the intersection of Highway I-85 & Cole Mill Rd, two miles from Duke University and Duke Medical Center. North Carolina Central University is six miles from our front door and downtown Durham attractions such as Durham Performing Arts Center, Durham Bulls Athletic Park, restaurants, and bars is only four miles away. Breakfast, WiFi, and our five-mile radius shuttle service are included in your stay, as well as access to our fitness center and indoor heated pool.
Location
Hampton Inn & Suites Durham University Medical Center
Guests consistently praised the hotel for its cleanliness, noting spotless rooms and common areas.
Staff Service
The staff received high marks for being friendly, helpful, and accommodating, with particular mentions of Priscilla, Wayne, and Mimi.
Breakfast Quality
The breakfast offerings were frequently highlighted as exceptional, with a wide variety of options that exceeded typical hotel standards.
Comfortable Rooms
Many reviews noted the spacious and comfortable rooms, with good amenities and comfortable beds.
Location
The hotel is conveniently located near Duke Medical Center and various dining options, making it ideal for visitors.
BJ
Brandon Johnston
6 days ago
5.0
Cleanest Hilton line hotel I have stayed at. Plenty of east food choices within walking distance. Will stay here every time Iām in the area. Hopefully being new does not wear off with upkeep of the property and rooms.
IC
Ir Clinton
Nov 13, 2025
5.0
Desk staff excellent
LW
Larry Whitley
Nov 12, 2025
5.0
Back again for my wife's medical appointments.. always enjoy the hotel and Gwen you are the best driver. We appreciate you so much. NASCAR could use you
DH
Diane Hooper
Oct 12, 2025
5.0
This is the best Hampton Inn we've ever stayed at, definitely 5 stars. It looks new, very clean, with an amazing first floor level. Front desk was very friendly, always staffed, bottled water was in our room. The hallway and room was spotless and comfortable. Breakfast area is huge, lots of seating, large selection, multiple waffle irons, much more than other Hampton Inns. Definitely recommend!
OB
Opici Becton
Sep 19, 2025
5.0
My family was in town for our Aunts Funeral and most family members who come from up North like downtown durham accommodations. But we were able to get them to stay here and they are so happy with the hotel, the breakfast and location to the family house is around the corner. The expectation of home away from home was super š. Thank you so much. Plenty seating and the view of the back where you had plenty sun space. I may do a Friday home away from home stay myself. Whewwww! And Ms. Terry was absolutely amazing...greeting guest and welcoming those coming in to check in. Keep up the amazing job and lets not forget those who keep the hotel clean and put the breakfast spread out ...Thank you allllll! This will be our family hotel.