Holiday Inn St Louis SW - Route 66 by IHG

4.0
1432 reviews
Welcome to our stylish St. Louis Hotel SW - Route 66.

About

HotelWedding VenueBusiness Meeting LocationsConference CenterHoliday Inn
Experience the charm of St. Louis at the renovated Holiday Inn St Louis SW - Route 66, a hotel blending utmost comfort with a prime location and exceptional service to provide an unforgettable stay. Located on historic Route 66 at highways I-44 and I-270, just 20 minutes from St. Louis Lambert International Airport, we offer easy access to top St. Louis attractions like the Gateway Arch, Missouri Botanical Garden, and the St. Louis Zoo. Catch a St. Louis Cardinals game at Busch Stadium, and visit the Magic House, St. Louis Science Center, Six Flags, or World Wide Technology Soccer Park. Business travelers appreciate proximity to companies like Maritz and Harris-Stowe and top medical centers like Barnes-Jewish Hospital, St. Louis Children's Hospital, SSM Health, and Mercy Hospital. Enjoy top amenities like a resort-style outdoor pool with luxury cabanas and a state-of-the-art Fitness Center. Relax by our fire pit with a cocktail or play yard games with family or friends. Savor delicious dining at our award-winning steakhouse, Twisted Tree Steakhouse, plus breakfast at Wakey Wakey Breakfast Place and cocktails at Luxe Libations: The Lounge by Twisted Tree. From our elegant Sunset Event Center venues to complimentary parking, free Wi-Fi, and spacious rooms and suites, we are the ideal choice for an exciting and enjoyable stay in St. Louis.

Location

Holiday Inn St Louis SW - Route 66 by IHG
10709 Watson Road, St. Louis, MO
63127, United States

Hours

Reviews

4.0
1,432 reviews
5 stars
644
4 stars
401
3 stars
190
2 stars
79
1 star
118

What are people saying?

AI-generated from recent customer reviews

Staff Service

Many customers praised the friendly and helpful staff, particularly mentioning individuals like Caroline and Mark for their exceptional service.

Cleanliness

Overall, guests found the hotel clean, although some reported issues with specific rooms not being spotless.

Amenities

The hotel features a nice pool area, a well-equipped gym, and an attached restaurant that received positive feedback for its food.

Room Quality

While many guests appreciated the updated rooms, some noted that bathrooms were small and there were issues with noise from adjoining rooms.

Location

The hotel is well-located near shopping and dining options, making it convenient for guests.
  • BF
    Brian Fole
    2 days ago
    1.0
    Came here with my family and tried to speak with the manager of this location about accommodatios for my child with down syndrome. Ashley seemed to not care at all. She was at the front desk talking with someone about her wedding plans and seemed to dismiss all of my concerns. My child is very sensitive to these type of situations. As a manager, please show more compassion. Everyone else seemed very pleasant.
  • KL
    Kellie Lohmeyer
    Jan 1, 2026
    5.0
    Also, their conference spaces and setups are excellent! I personally LOVED the Christmas decorations this year. Previous years they didn't have any decorations.
  • KL
    Kenzie Lake
    Dec 29, 2025
    5.0
    Honestly the best hotel I've stayed at in my life. Staff was super friendly, we have some favorite ladies, I hope they see this! They made our stay so wonderful! I highly recommend staying here!
  • DM
    Dave M
    Dec 25, 2025
    5.0
    Easily our favorite Holiday Inn! Updated rooms that are very nice, excellent front desk staff, lots of parking, and a great location. A fireplace and large-screen televisions in the lobby, a good gym with a lot of options, and an outstanding pool area. Plus, an attached lounge and restaurant. The hotel is professionally themed with Route 66 decorations. We highly recommend this hotel.
  • RH
    Robert Hom
    Dec 9, 2025
    5.0
    This Holiday inn is located towards the Southwest of St Louis which seems to be a safer area with a lot of shopping and food surrounding it. There seems to be a plaza right across the street with good food options. The rooms were really clean and the bed was really comfortable. The vibe of the place seems to focus on route 66. My room had the view of the pool which actually looked really nice. I was there during cold season so there wasn't really much going on at the pool scene. There is a really nice restaurant and bar in the lobby area which has some pretty awesome food if you don't want to leave the hotel itself. The staff is really nice and helpful and was able to answer most of my questions or actually all of my questions whenever I approached them. There's a conference room area which I believe is used for small conventions. Overall, I would stay here again if I'm ever in the St Louis area. But, I highly doubt I'll ever go back. πŸ˜…

Frequently Asked Questions About Holiday Inn St Louis SW - Route 66 by IHG

Are there business-friendly amenities at Holiday Inn St Louis SW – Route 66?

Yes, Holiday Inn St Louis SW – Route 66 includes a 24-hour Business Center with computers, printers, fax services, and shipping optionsβ€”ideal for business travelers and remote work needs.

Is the hotel pet-friendly?

Yes, the hotel is pet-friendly, welcoming your furry friends with comfortable accommodations. There are designated pet-friendly rooms and nearby parks for easy walks.