Holiday Inn Express & Suites St. Louis South - I-55 by IHG

4.6
656 reviews
Welcome to the Holiday Inn Express & Suites St. Louis South I-55

About

HotelWedding VenueBusiness Meeting Locations
Welcome to the new Holiday Inn Express & Suites St. Louis South I-55! South St. Louis's newest and most modern Holiday Inn Express Hotel nestled within a growing development at the intersection of Butler Hill Road & I-55 just one mile south of I-270/255 with access to everything St. Louis has to offer. The hotel is just 14 miles directly south of Downtown St. Louis and located at exit #195 from I-55. Business travelers will benefit from our central location with easy on/off access to I-55 that offers access to the different areas of St. Louis within minutes. The hotel complex includes the Barnes-Jewish Siteman Cancer Center & Mercy Health. We are just minutes from Metlife, Anhueser Busch, Cigna and the National Cemetary Association. Our non smoking Holiday Inn Express & Suites St. Louis I-55 hotel is very convenient to guests visiting Busch Stadium, Gateway Arch, Grant's Farm, Magic House, St. Louis Science Center, St. Louis Zoo, Forest Park, River City Casino and much more! Hotel Guests can enjoy an array of amenities including guest room suites, Indoor Pool, Suite Shop, Two Meeting Rooms, Complimentary Express Start Breakfast, Complimentary High Speed Wired & Wireless Internet, Comfortable Great Room with Outdoor Patio and warm Cookies & Milk served nightly. Guests will enjoy our midwest hospitality in South St. Louis. Our goal is to make every guest feel at home so that we exceed all of their expectations!

Location

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
4250 Midamerica Lane, St. Louis, MO
63129, United States

Hours

Reviews

4.6
656 reviews
5 stars
487
4 stars
120
3 stars
29
2 stars
7
1 star
13

What are people saying?

AI-generated from recent customer reviews

Cleanliness

Most guests reported clean and well-maintained rooms, although a few noted issues with specific rooms.

Staff Service

The staff received high praise for being friendly, accommodating, and helpful throughout guests' stays.

Breakfast Quality

Breakfast was generally well-received, with many guests enjoying the variety and quality, though some suggested improvements.

Location

The hotel is conveniently located with easy access to highways and nearby attractions.

Amenities

Guests appreciated the additional amenities like evening cookies, a pool, and comfortable beds, although some had concerns about noise and specific room features.
  • SD
    Susan Dickey
    Nov 10, 2025
    5.0
    Friendly staff! Very nice atmosphere! I would definitely recommend it!
  • RH
    Robin Hudson
    Nov 4, 2025
    5.0
    Always there to help make sure I get a ♿️ handicap room with a seat in the shower .
  • JG
    Justin Garza
    Oct 14, 2025
    5.0
    Easy to get to location. Clean rooms and very friendly staff
  • TH
    Tony Herrera
    Oct 14, 2025
    5.0
    I will visit again in the future. Great experience and hotel was new and clean throughout.
  • JH
    James Holstein
    Sep 20, 2025
    5.0
    Loved the friendly staff

Frequently Asked Questions About Holiday Inn Express & Suites St. Louis South - I-55 by IHG

What time is check-in and check-out at Holiday Inn Express & Suites St. Louis South - I-55?

Check-in time is 3:00 PM and check-out time is 11:00 AM.

Is breakfast included during the stay?

Yes, a complimentary Express Start breakfast with buffet options is available for free.