Welcome to the new Holiday Inn Express & Suites St. Louis South I-55!
South St. Louis's newest and most modern Holiday Inn Express Hotel nestled within a growing development at the intersection of Butler Hill Road & I-55 just one mile south of I-270/255 with access to everything St. Louis has to offer. The hotel is just 14 miles directly south of Downtown St. Louis and located at exit #195 from I-55.
Business travelers will benefit from our central location with easy on/off access to I-55 that offers access to the different areas of St. Louis within minutes. The hotel complex includes the Barnes-Jewish Siteman Cancer Center & Mercy Health. We are just minutes from Metlife, Anhueser Busch, Cigna and the National Cemetary Association.
Our non smoking Holiday Inn Express & Suites St. Louis I-55 hotel is very convenient to guests visiting Busch Stadium, Gateway Arch, Grant's Farm, Magic House, St. Louis Science Center, St. Louis Zoo, Forest Park, River City Casino and much more!
Hotel Guests can enjoy an array of amenities including guest room suites, Indoor Pool, Suite Shop, Two Meeting Rooms, Complimentary Express Start Breakfast, Complimentary High Speed Wired & Wireless Internet, Comfortable Great Room with Outdoor Patio and warm Cookies & Milk served nightly.
Guests will enjoy our midwest hospitality in South St. Louis. Our goal is to make every guest feel at home so that we exceed all of their expectations!
Location
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Most guests reported clean and well-maintained rooms, although a few noted issues with specific rooms.
Staff Service
The staff received high praise for being friendly, accommodating, and helpful throughout guests' stays.
Breakfast Quality
Breakfast was generally well-received, with many guests enjoying the variety and quality, though some suggested improvements.
Location
The hotel is conveniently located with easy access to highways and nearby attractions.
Amenities
Guests appreciated the additional amenities like evening cookies, a pool, and comfortable beds, although some had concerns about noise and specific room features.
SD
Susan Dickey
Nov 10, 2025
5.0
Friendly staff! Very nice atmosphere! I would definitely recommend it!
RH
Robin Hudson
Nov 4, 2025
5.0
Always there to help make sure I get a ♿️ handicap room with a seat in the shower .
JG
Justin Garza
Oct 14, 2025
5.0
Easy to get to location. Clean rooms and very friendly staff
TH
Tony Herrera
Oct 14, 2025
5.0
I will visit again in the future. Great experience and hotel was new and clean throughout.
Frequently Asked Questions About Holiday Inn Express & Suites St. Louis South - I-55 by IHG
What time is check-in and check-out at Holiday Inn Express & Suites St. Louis South - I-55?
Check-in time is 3:00 PM and check-out time is 11:00 AM.
Is breakfast included during the stay?
Yes, a complimentary Express Start breakfast with buffet options is available for free.
Does the hotel provide free Wi-Fi access?
Yes, free Wi-Fi is available in public areas of the hotel.
Is the Holiday Inn Express & Suites St. Louis South - I-55 accessible for guests with mobility needs?
Yes, the hotel offers accessible parking and is mobility accessible with elevator access.
Are pets allowed at the hotel?
No, pets including cats and dogs are not allowed at this property.
What kind of fitness facilities does the hotel provide?
The hotel offers a free fitness center equipped with elliptical machines, treadmills, and free weights.
Are there any meeting or business facilities available?
Yes, the hotel features two meeting rooms and a business center for guest use.
Is there on-site baggage storage and housekeeping services?
Yes, baggage storage is available and housekeeping services are provided daily.
What nearby medical facilities are close to the hotel?
Nearby medical facilities include Mercy Family Physicians, Mercy Clinic OB/Gyn - Butler Hill, Mercy Clinic Primary Care - Butler Hill, and Barnes-Jewish Heart and Vascular Center.
What dining options are available near the hotel for a quick meal?
Nearby dining options include Taco Bell, Pizza Hut Express, Popeyes® Louisiana Kitchen, and Burger King for fast-food and casual meals.
Where can guests fuel their vehicles or find convenience stores near Holiday Inn Express & Suites St. Louis South - I-55?
Guests can find gas stations and convenience stores such as Phillips 66 Gas, Petro Mart, Rocket, and another Phillips 66 nearby for fuel and supplies.