Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • May 03, 2026
HotelWedding VenueBusiness Meeting LocationsHoliday Inn Express
Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!
Location
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • May 03, 2026
Holiday Inn Express & Suites Cape Girardeau I-55 by IHG
Certified by Holiday Inn Express & Suites Cape Girardeau I-55 by IHG • May 03, 2026
MondayOpen 24 hours
TuesdayOpen 24 hours
WednesdayOpen 24 hours
ThursdayOpen 24 hours
FridayOpen 24 hours
SaturdayOpen 24 hours
SundayOpen 24 hours
Reviews
4.6
813 reviews
5 stars
606
4 stars
136
3 stars
33
2 stars
13
1 star
25
JS
Jessie Spitzer
5 days ago
2.0
I expected better. A hot tub was shown online.. spoiler alert, there isn’t one. Bathtub was painted and peeling/chipping paint. I only discovered this because our toddlers were so cold from the pool we had to warm them up with a bath. It was gross! Pieces big and small floating around in the bath. Breakfast food was pretty disappointing as well. The eggs were like play-doh, bacon questionable. Employees were nice and location felt safe, but I wouldn’t stay here again.
LW
Lydia Wueen
Apr 29, 2026
4.0
Cons: The lady who checked me out was very rude and short. Seemed like I was bothering her by checking out. Breakfast was very average, not good not bad.
Plus: The evening staff that checked me in and late night staff were very helpful and friendly though! Rooms were very spacious and clean! Housekeepers were very polite and friendly when passing them in the hall. Very close to 55 and shopping areas!
KK
Katie
Apr 20, 2026
5.0
Great hotel. Nice big rooms. Very clean. The front desk clerk was very friendly. They have cookies and milk at 8 pm. Great location.
SS
STLA_1020
Apr 14, 2026
5.0
Another great IHG experience. Staff were all very friendly and helpful. Especially at check in. Room was very clean, bed extremely comfortable. The pool area is very nice. Also have a small gym (could use a bit more there but still good). Will definitely be back again
AS
Ashley Sanders
Apr 10, 2026
5.0
This was a great stay and one of the nicer and more updated Holiday Inn Express hotels we’ve stayed at! It’s a great find and so convenient to so many restaurants! The bed and pillows were comfy and the room was great!
Frequently Asked Questions About Holiday Inn Express & Suites Cape Girardeau I-55 by IHG
What are the check-in and check-out times at Holiday Inn Express & Suites Cape Girardeau I-55?
Check-in time is at 3:00 PM and check-out time is at 11:00 AM.
Is breakfast included during my stay at this hotel?
Yes, a free buffet breakfast is available for all guests.
Does the hotel offer free Wi-Fi?
Yes, free Wi-Fi is available in public areas throughout the hotel.
Are there fitness facilities available at the hotel?
Yes, the hotel has a fitness center with elliptical machines, free weights, and treadmills available for free use.
Is parking available at the Holiday Inn Express & Suites Cape Girardeau I-55?
Yes, free parking is available for all guests.
Does the hotel provide accommodations accessible for guests with mobility challenges?
Yes, the hotel is mobility accessible and offers accessible parking and an elevator.
Are pets allowed at the hotel?
No, pets including cats and dogs are not allowed on the property.
What nearby attractions can I visit while staying at the Holiday Inn Express & Suites Cape Girardeau I-55?
Guests can visit Southeast Missouri State University to enjoy sports events, explore the Old Downtown area for shops and restaurants along the Mississippi River, and spend time outdoors at Trail of Tears State Park with activities such as hiking, biking, and fishing.
Are there any nearby dining options around the hotel?
Yes, nearby dining options include Olive Garden for Italian cuisine, Popeyes® Louisiana Kitchen for fast food, Panera Bread for coffee and bakery items, Red Lobster for seafood, and Cracker Barrel Old Country Store for American and barbecue dishes.
Can I hold business meetings or events at the Holiday Inn Express & Suites Cape Girardeau I-55?
Yes, the hotel has two spacious meeting rooms equipped with audio/visual equipment, suitable for business functions and special events.
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