From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street.
The hotel is frequently praised for its cleanliness, with many guests noting that both rooms and public areas are well-maintained.
Staff Service
Guests consistently highlight the friendly and helpful nature of the staff, contributing to a positive overall experience.
Breakfast Quality
While many guests enjoyed the breakfast offerings, some noted that it could be improved, with a few describing it as standard or lacking excitement.
Room Comfort
Feedback on room comfort is mixed; while many found the rooms spacious and comfortable, some mentioned issues with bed firmness and noise from neighboring rooms.
Location
The hotel is conveniently located near restaurants and highways, making it a favorable choice for travelers.
T9
team kenny 99
3 days ago
5.0
Iāve stayed here multiple times and have always had a good experience. The staff is friendly, the rooms are consistently clean and inviting, and check-in is easy. Breakfast is included and is passableānothing fancy, but it gets the job done. Overall, itās a reliable place to stay and Iād come back again.
BB
Barbara B.
4 days ago
5.0
My husband and I were traveling during college football playoffs and wanted to make sure we stayed at a motel with ESPN. I called the Hampton in Cape Girardeau and spoke with a delightful young woman named Tonja. She checked to make sure that the motel did indeed have ESPN and that there were no problems with streaming. I thanked her for her troubles, and she told me that all of the employees there are dedicated to making sure their guests have a pleasant stay. Our stay was great. The bed was comfy and not rock hard as many motel beds are. Everything was clean and quiet. Staff were great. For motel breakfast, the breakfast was good. Give Tonja a raise, she is a great asset.
LL
Laura L
Jan 4, 2026
5.0
Clean comfortable rooms, not a fan of the sliding bathroom door that can't be locked, but not a deal breaker.
Convenient to the interstate.
Staff is friendly and professional.
LP
Leticia Price
Jan 3, 2026
5.0
The staff were incredibly friendly and helpful. I had a stained pillow case and they offered to remake the whole bed, but we declined the offer and just replacd the pillowcase. The whole room was clean and comfortable. And my husband was happy to find they offered biscuit and gravy for breakfast! The hotel definitely deserved the awards they have earned.
Oh and they had evening cookies for guests! šŖ
WB
William Brown
Dec 23, 2025
5.0
Very nice property convenient to interstate travelers.
Frequently Asked Questions About Hampton Inn Cape Girardeau I-55 East
What are the check-in and check-out times at Hampton Inn Cape Girardeau I-55 East?
Check-in is at 3:00 PM and check-out is at 11:00 AM at Hampton Inn Cape Girardeau I-55 East.
Is breakfast included with a stay at Hampton Inn Cape Girardeau I-55 East?
Yes, the hotel offers free breakfast with a buffet breakfast option available.
Does the hotel provide free Wi-Fi access to guests?
Yes, free Wi-Fi is available in public areas, along with a public internet terminal for guest use.
Are pets allowed at Hampton Inn Cape Girardeau I-55 East?
Yes, pets including cats and dogs are welcome at the hotel.
What accessibility features does Hampton Inn Cape Girardeau I-55 East offer?
The hotel provides accessible parking, an elevator, and is mobility accessible to accommodate guests with disabilities.
Is parking available at the hotel, and is there a cost?
Self-parking is available for free at Hampton Inn Cape Girardeau I-55 East.
What fitness facilities are available at Hampton Inn Cape Girardeau I-55 East?
Guests have free access to a fitness center equipped with elliptical machines and treadmills.
Are there any nearby medical facilities or clinics close to the hotel?
Yes, nearby medical facilities include Kaelin Dental Group, Mercy Clinic Endocrinology - Doctors Park, Cancer Institute, and Olson Pediatrics, convenient for guests needing medical care.
What dining options are available near Hampton Inn Cape Girardeau I-55 East?
Nearby dining options include Twisted Biscuit Brunch Co., Cracker Barrel Old Country Store, Texas Roadhouse, and El Acapulco, offering a range of cuisines close to the hotel.
Are there any event or banquet centers near the hotel for hosting gatherings?
Yes, Rays Plaza Banquet Center and Ray's Plaza Banquet Center are nearby venues suitable for events and catering services.