Hotel By St Mary's Hospital - Rochester Mayo Clinic
Welcome to the Holiday Inn Express & Suites Rochester - Mayo Clinic Area hotel, located just 2.5 blocks west of St. Mary’s Hospital, and less than a mile from Mayo Clinic, the Gonda building, and the Eisenberg building. You'll find us on the corner of Hwy 52 and 2nd Street SW, making it easy to come and go as you please from our underground heated parking garage. Our hotel offers shuttle service to the hospital and clinic on weekdays for your convenience if you don't want to drive. And the Rochester International Airport is only 9 miles from us.
The Rochester Holiday Inn Express is a great hotel for families while visiting the area. We are near some of Rochester's best attractions including the Mayo Civic Center, Silver Lake, Minnesota Children's Museum of Rochester, and the History Center of Olmsted County.
After a long day, we hope you take the chance to visit one of the great local restaurants we have near the hotel like Canadian Honker, Cafe Presto, or Tonic that are just steps away from our door. We are even near popular chain restaurants including TGI Fridays, Olive Garden, and Famous Dave's.
We hope your stay at the Holiday Inn Express Rochester, MN is a pleasant one.
Location
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Most guests found the hotel clean, but some reported issues with room cleanliness and maintenance.
Staff Service
The staff received high praise for being friendly, accommodating, and helpful throughout guests' stays.
Location
The hotel is conveniently located near the Mayo Clinic, making it a preferred choice for patients and visitors.
Amenities
Guests appreciated the shuttle service and breakfast options, but there were complaints about the hot tub and pool being out of order.
Noise Issues
Several reviews mentioned noise disturbances from nearby traffic and loud guests, impacting the quality of sleep.
SS
Scott Sheldon
5 days ago
5.0
Tons of restaurants within a block of the location.
JG
Jody Geyssens
Nov 9, 2025
2.0
Nice hotel. Kinda of pricey for what it is.. Don't leave anything in your room when you check out. You will never get it back. It magically disappears.
TB
Teresa Bear
Nov 7, 2025
1.0
One of the worst hotels we’ve ever stayed in. The furniture is stained, broken and filthy. The shower head is rusty. One of the staff was out front underneath our second floor window at 3:45am yelling and screaming for over 30 minutes.
LF
Lauri Formea
Oct 19, 2025
5.0
Very nice, clean hotel within minutes of Mayo Clinic. Shuttle pick up at the door was wonderful, too! Courteous staff and rooms and beds were comfortable.
TG
Teresa General
Oct 17, 2025
5.0
There is a side street that runs close to the hotel. The local street speed car drivers race down that street all night long. I might have gotten 2 and a half hours in one night.
Frequently Asked Questions About Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
What are the check-in and check-out times at Holiday Inn Express & Suites Rochester – Mayo Clinic Area?
Check-in time is at 3:00 PM and check-out time is at 11:00 AM.
Does the hotel provide free breakfast during a stay?
Yes, the hotel offers a complimentary breakfast with buffet options.
Is parking available for guests, and is it free?
Yes, free parking is available for guests.
Does the hotel allow pets?
Yes, pets including dogs are welcome at the hotel.
Are there fitness facilities available on-site?
Yes, the hotel has a free fitness center with free weights and a treadmill.
Is there a shuttle service available from the hotel?
Yes, a local shuttle is available on weekdays to St. Mary’s Hospital and Mayo Clinic.
What nearby dining options are available near the hotel?
Near the hotel, you can find restaurants such as Canadian Honker, Cafe Presto, Tonic, TGI Fridays, Olive Garden, Famous Dave’s, Jersey Jo’s, Toppers Pizza, Cherry Berry Yogurt Bar, KFC, McDonald’s, and Plaza Morena.
Are there convenient shops and services close to the hotel?
Yes, nearby places include Fresh Thyme Market for groceries, Edible Arrangements for gifts, Rocco Altobelli Salons & Day Spas, Posh Boutique, Joe’s Liquor, and several convenience stores such as Circle K and Holiday Stationstores.
How can I reach the hotel from the Rochester International Airport?
The hotel is approximately 9 miles from Rochester International Airport, and you can reach it easily by car or taxi. On weekdays, a hotel shuttle service is available to nearby key locations.
Is the hotel accessible for guests with mobility needs?
Yes, the hotel is mobility accessible and has accessible parking and elevators to assist guests.