Our all-suite hotel is your home away from home. We offer spacious accommodations with a separate seating area including a sofa sleeper in all rooms so you can relax whether traveling for work, pleasure or medical treatment. Guests can enjoy our complimentary Hot Breakfast Buffet, free High-Speed Internet, On-Site Business Center, and complimentary shuttle service to Mayo Clinic and St Mary's Hospital. In addition, our fitness center, heated indoor pool and whirlpool are a great way to relax after a long day.
Stay in comfortable suites with premium bedding, a microwave and refrigerator, a work desk and a 50" TV. All rooms also have a coffee maker and USB ports. We’re located mere minutes from the Mayo Clinic and St. Mary’s Hospital, so you won’t need to commute far. Step across the street to The Shoppes at Maine for dining and shopping or head into downtown Rochester for some local dining and shopping.
Location
Holiday Inn Express Rochester South - Mayo Area by IHG
Hotel was nice and clean. Breakfast was good. Unfortunately the tv guide was not accurate or not had all the channels available.
JM
Justin Moline
Nov 4, 2025
4.0
I recently stayed at the Holiday Inn Express & Suites at 4141 Maine Ave SE in Rochester, MN, and overall, it was a pleasant experience during our road trip. The front desk staff were incredibly friendly and welcoming, which set a great tone right from check-in.
The room was clean, comfortable, and well-maintained, and the lobby had a nice, modern feel. I appreciated the breakfast area, which offered a good variety of options to start the day. One standout feature was the bean-to-cup fresh coffee machine—it made for a delicious, high-quality brew that felt like a treat.
On the downside, I was surprised by the $2.00 fee for the in-room safe; that's the first time I've encountered that at any hotel, and it felt unnecessary. We were on the first floor, and getting hot water for the shower took longer than expected—about 5 to 10 minutes of running the tap before it warmed up. It seemed like the hot water recirculation system might not be functioning properly, but once the water got hot, it stayed consistent throughout the shower.
A big plus after a long day of driving was the hot tub—it was a relaxing way to unwind and exactly what we needed. I'd recommend this hotel for its cleanliness, friendly service, and amenities, though they could address those minor issues for an even better stay
SS
Steve Smith
Oct 7, 2025
2.0
The room was fine, staff not so much.
BC
b c
Oct 2, 2025
4.0
Funny smell in room. Breakfast closed early and not restocked.
MC
Michelle Carver
Sep 25, 2025
1.0
Worst people at the front desk, clearly do not know the law but Attorney Vargas will reach out soon. Threaten me with a service animal, I came in town to work with a service dog for seizures. Even offered to show paperwork to 4 different people who asked the same questions. One guy even wrote the information on my check in slip. The next woman lied saying I snuck my dog in through the back door. I told them to review cameras and they refused, though I continued to be threatened to be kicked out for my dog barking…who is a service animal. I’m just glad I recorded the harassment and discrimination.
Frequently Asked Questions About Holiday Inn Express Rochester South - Mayo Area by IHG
What are the check-in and check-out times at Holiday Inn Express Rochester South - Mayo Area by IHG?
Check-in time is 3:00 PM and check-out time is 11:00 AM.
Is free breakfast available at Holiday Inn Express Rochester South - Mayo Area by IHG?
Yes, a complimentary hot breakfast buffet is available for guests.
Does this hotel allow pets?
Dogs are allowed, but cats and other pets are not permitted.
Is the hotel accessible for guests with mobility needs?
Yes, the hotel provides accessible parking and is mobility accessible with elevators available.
Is Wi-Fi available at the hotel and is it free?
Free Wi-Fi is available in public areas of the hotel.
Are there any fitness or recreational facilities at the hotel?
Yes, there is a fitness center, a heated indoor pool, and a hot tub available for guests.
What safety and sanitation measures are in place at the hotel?
The hotel uses commercial-grade disinfectants, enhanced cleaning in common areas and guest rooms, offers sanitizer, and practices safe food handling procedures. High-touch items are removed from common areas and guest rooms.
Are there any nearby shopping or dining options close to the hotel?
Yes, The Shoppes at Maine is located just across the street offering dining and shopping options, and downtown Rochester is nearby for additional local shopping and dining experiences.
What cinemas are near Holiday Inn Express Rochester South - Mayo Area by IHG for entertainment?
Nearby cinemas include Rochester Cinema + Imax Rochester, Mn, Marcus Wehrenberg Rochester Cinema, and Marcus Rochester Cinema, providing great entertainment options for guests.
Are there other hotels nearby if I'm looking for additional accommodation options?
Yes, nearby hotels include Comfort Suites, Spark by Hilton Rochester South, Microtel Inn & Suites by Wyndham Rochester South Mayo Clinic, and La Quinta Inn and Suites by Wyndham Rochester Mayo Clinic.