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H-E-B Pharmacy

3.8
(70 reviews)

Business Details

20935 US Highway 281 North, San Antonio, TX
78258, United States
(210) 491-2450
https://www.heb.com/pharmacy

About

PharmaciesH-E-B Pharmacy
H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 20935 US Highway 281 North in San Antonio, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.

Details

  • DeliveryAvailable
  • Requires appointmentNot available
  • Credit cardAvailable
  • DebitAvailable

Location

H-E-B Pharmacy
20935 US Highway 281 North, San Antonio, TX
78258, United States

Hours

Monday8:00 AM - 8:00 PM
Tuesday8:00 AM - 8:00 PM
Wednesday8:00 AM - 8:00 PM
Thursday8:00 AM - 8:00 PM
Friday8:00 AM - 8:00 PM
Saturday9:00 AM - 6:00 PM
Sunday10:00 AM - 5:00 PM

Reviews

3.8
70 reviews
5 stars
42
4 stars
7
3 stars
3
2 stars
2
1 star
16
  • CC
    Caley Cunningham
    Sep 28, 2026
    5.0
    I can't say enough good things about the H-E-B Pharmacy team, especially Kim. She was a total lifesaver right before my trip, going above and beyond to make sure my medication was ready ASAP. She was so positive and proactive in getting it done, and even gave me a courtesy call as soon as it was ready. Kim’s exceptional service really made a lasting impression on me and I can't thank her enough!
  • EC
    Elizabeth Carroll-Stivers
    May 7, 2026
    5.0
    Easy in and out!
  • DF
    Devin Faulkner
    Apr 17, 2026
    5.0
    Great customer service
  • CG
    Charlene Gieptner
    Nov 14, 2025
    5.0
    EXCELLENT!!!!!! So very nice and always willing to help and explain all about the medications if they are new to you. Thank you for always having such a nice staff.
  • TT
    Timothy Tillman
    Oct 21, 2023
    2.0
    I keep trying to go to HEB for Vaccinations but even after having an appointment my wife and I wait for over an hour every time. From now on, we will just go to our GP’s office for our Vaccinations.

Frequently Asked Questions About H-E-B Pharmacy

Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?

Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions

Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?

COVID-19 and flu vaccines are available on both a walk-in or appointment basis

Brand Certified Facts from H-E-B Pharmacy

This information is certified by H-E-B Pharmacy and published from the brand's official system of record. Data is distributed through an enterprise-grade knowledge management platform. Learn more about our data sources
Certified October 04, 2026Yext Knowledge Graph
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