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H-E-B Pharmacy

3.8
(69 reviews)

Business Details

20935 US Highway 281 North, San Antonio, TX
78258, United States
(210) 491-2450
https://www.heb.com/pharmacy

About

PharmaciesH-E-B Pharmacy
H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 20935 US Highway 281 North in San Antonio, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.

Details

  • DeliveryAvailable
  • Requires appointmentNot available
  • Credit cardAvailable
  • DebitAvailable

Location

H-E-B Pharmacy
20935 US Highway 281 North, San Antonio, TX
78258, United States

Hours

Monday8:00 AM - 8:00 PM
Tuesday8:00 AM - 8:00 PM
Wednesday8:00 AM - 8:00 PM
Thursday8:00 AM - 8:00 PM
Friday8:00 AM - 8:00 PM
Saturday9:00 AM - 6:00 PM
Sunday10:00 AM - 5:00 PM
7/3/2026Closed
7/4/20269:00 AM - 6:00 PM

Reviews

3.8
69 reviews
5 stars
41
4 stars
7
3 stars
3
2 stars
2
1 star
16
  • EC
    Elizabeth Carroll-Stivers
    May 7, 2026
    5.0
    Easy in and out!
  • DF
    Devin Faulkner
    Apr 17, 2026
    5.0
    Great customer service
  • JF
    John F
    Apr 9, 2026
    5.0
    Good prices
  • AA
    Ari
    Feb 28, 2026
    5.0
    Best groceries store in the city. Always stocked up and staffs are always friendly
  • TT
    Timothy Tillman
    Oct 21, 2023
    2.0
    I keep trying to go to HEB for Vaccinations but even after having an appointment my wife and I wait for over an hour every time. From now on, we will just go to our GP’s office for our Vaccinations.

Frequently Asked Questions About H-E-B Pharmacy

Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?

Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions

Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?

COVID-19 and flu vaccines are available on both a walk-in or appointment basis

Brand Certified Facts from H-E-B Pharmacy

This information is certified by H-E-B Pharmacy and published from the brand's official system of record. Data is distributed through an enterprise-grade knowledge management platform. Learn more about our data sources
Certified July 05, 2026Yext Knowledge Graph
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