H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 721 Castroville Rd in San Antonio, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
Phone just rang and rang and nobody answered for 15 minutes. It was 10:30am, people. You can at least answer and put the call on hold.
Unacceptable.
JR
Jojo Rogerson
Apr 29, 2026
5.0
Very good service there
CP
Christopher Perez
Apr 28, 2026
1.0
I changed medications to be sent through this pharmacy and I have had the worse experience getting my medication. Every month my coupon is not being credited so I have to call back everytime to have it ran manually. Every phone call I have with the pharmacy is a gamble as they just pick up and immediately hang up. This is the worse experience I have ever had with an HEB.
LG
Liz Gonzalez
Feb 2, 2026
5.0
Friendly staff
NB
nyjha beck
Apr 10, 2024
1.0
Very long wait time and some of the staff can be very short and rude to you. I understand it may be a hard job, but why pick this industry if you can’t be courteous to people who have waited 30 minutes in line for prepaid medications.
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours of H-E-B Pharmacy at 721 Castroville Rd?
H-E-B Pharmacy is open Monday to Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy provide COVID-19 vaccinations and how can I get more information about them?
Yes, H-E-B Pharmacy offers COVID-19 vaccines. You can learn more about vaccine phases and FAQs at https://vaccine.heb.com/.
Can I get a COVID-19 or flu vaccine at H-E-B Pharmacy without an appointment?
Yes, COVID-19 and flu vaccines at H-E-B Pharmacy are available on a walk-in or appointment basis.
Does H-E-B Pharmacy offer delivery services for prescriptions?
Yes, H-E-B Pharmacy offers delivery services for prescriptions.
What payment methods are accepted at H-E-B Pharmacy?
H-E-B Pharmacy accepts American Express, Android Pay, Apple Pay, Cash, Check, Contactless Payment, Discover, Mastercard, Samsung Pay, and Visa.
Where can I find additional services provided by H-E-B Pharmacy?
You can view all H-E-B Pharmacy services at https://www.heb.com/pharmacy/common/landing.
What are some nearby places I can visit around H-E-B Pharmacy at 721 Castroville Rd?
Nearby places include Ezpawn pawn shop, Methodist Family Health Center - Las Palmas dental clinic, and La Fe Herb Shop pharmacy.
Are there dining options near H-E-B Pharmacy?
Yes, nearby dining options include Luby’s comfort food restaurant and J Anthony’s Seafood cafe and restaurant, perfect for a meal before or after your pharmacy visit.
What healthcare services are accessible near H-E-B Pharmacy?
Nearby healthcare facilities include Fresenius Kidney Care dialysis clinic, Dentistry for Children, and Family Planning Associates of San Antonio medical center.
How can I find convenient financial services near H-E-B Pharmacy?
Coinme currency exchange and ATMs, as well as Western Union money transfer services, are available close to H-E-B Pharmacy for your financial needs.
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