Brand Certified
H-E-B Pharmacy
3.4(81 reviews)
Certified by H-E-B Pharmacy • May 17, 2026
Business Details
19337 McDonald Street, Lytle, TX
78052, United States
Certified by H-E-B Pharmacy • May 17, 2026
(830) 772-5748
Certified by H-E-B Pharmacy • May 17, 2026
https://www.heb.com/pharmacy
Certified by H-E-B Pharmacy • May 17, 2026
About
Certified by H-E-B Pharmacy • May 17, 2026
PharmaciesH-E-B Pharmacy
H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 19337 McDonald Street in Lytle, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
Details
- DeliveryAvailable
- Requires appointmentNot available
- Credit cardAvailable
- DebitAvailable
Location
Certified by H-E-B Pharmacy • May 17, 2026
Hours
Certified by H-E-B Pharmacy • May 17, 2026
Monday8:00 AM - 8:00 PM
Tuesday8:00 AM - 8:00 PM
Wednesday8:00 AM - 8:00 PM
Thursday8:00 AM - 8:00 PM
Friday8:00 AM - 8:00 PM
Saturday9:00 AM - 6:00 PM
Sunday10:00 AM - 5:00 PM
5/25/20268:00 AM - 8:00 PM
Reviews
3.4
81 reviews
5 stars
43
4 stars
5
3 stars
4
2 stars
3
1 star
26
- MRMaria Gutierrez Rodriguez1 day ago5.0HEB my favorite grocery store 😊
- MHM HMay 7, 20261.0Have a problem with this heb I recently went in to purchase a few things i noticed a pokemon vending machine so I decided to check it out after i was done but I couldn't check it because the store manager Bryan was standing right in front of it not allowing us to check it i think management needs to do something about this
- DSDarrel StanleyApr 16, 20261.0I am moving pharmacies! This place has the worst customer service I have ever experienced. 50% of the time when the doctor calls in a prescription for my elderly mother the pharmacist won’t fill it or delays the prescription! This unacceptable .
- LMLife Adventure MapMar 22, 20265.0Picked up what I needed… quick, fast, easy, and the staff is always kind and helpful. I always have a great experience.
- GGGavin GonzalezMar 3, 20261.0I’ll be moving my meds to another pharmacy. On multiple occasions I have been texted that my prescriptions are ready only for parts to be missing or the entire prescription to be missing. Today that happened again except this time they asked me to loop the drive through line again or go inside and wait. Today’s experience took an hour. Don’t put your prescriptions at the Lytle HEB.
Frequently Asked Questions About H-E-B Pharmacy
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours of H-E-B Pharmacy in Lytle, TX?
H-E-B Pharmacy in Lytle is open Monday through Friday from 8:00 AM to 8:00 PM, Saturdays from 9:00 AM to 6:00 PM, and Sundays from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy in Lytle offer COVID-19 and flu vaccines?
Yes, H-E-B Pharmacy provides COVID-19 and flu vaccines, which are available on a walk-in or appointment basis.
How can I get the latest updates on COVID-19 vaccines from H-E-B Pharmacy?
You can visit https://vaccine.heb.com/ for the latest vaccine news, phases, and FAQs related to COVID-19 offered by H-E-B Pharmacy.
Does H-E-B Pharmacy offer delivery services for prescriptions?
Yes, H-E-B Pharmacy provides delivery services for prescriptions.
What payment methods are accepted at H-E-B Pharmacy in Lytle?
H-E-B Pharmacy accepts American Express, Mastercard, Visa, Discover, cash, check, Apple Pay, Android Pay, Samsung Pay, and contactless payments.
Where is H-E-B Pharmacy located in Lytle?
H-E-B Pharmacy is located at 19337 McDonald Street, Lytle, TX 78052, United States.
Are appointments required for vaccinations at H-E-B Pharmacy in Lytle?
No, appointments are not required for COVID-19 and flu vaccinations; walk-ins are welcome.
What nearby places can I visit before or after my pharmacy visit at H-E-B Pharmacy?
Nearby you can visit restaurants like Honeysuckle White, Taco Bell, and Whataburger for a meal, or enjoy services at Great Clips salon and Lytle Nail and Spa for beauty treatments.
Is there a grocery store near H-E-B Pharmacy in Lytle for convenient shopping?
Yes, the main H-E-B grocery store and H-E-B Fresh Bites convenience store are nearby, making it easy to combine your pharmacy visit with grocery shopping.
Are there any transportation or travel options near H-E-B Pharmacy in Lytle?
While there is no direct transit station mentioned, nearby places like Days Inn by Wyndham San Antonio Lytle hotel can accommodate travelers visiting the area, and services like Margo Bitcoin ATM and Redbox offer added convenience.
Brand Certified Facts from H-E-B Pharmacy
This information is certified by H-E-B Pharmacy and published from the brand's official system of record. Data is distributed through an enterprise-grade knowledge management platform. Learn more about our data sources
Certified May 17, 2026Yext Knowledge Graph
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