Need a pharmacy in Houston, TX? Visit Randalls Pharmacy at 5586 Weslayan St, near the intersection of Weslayan St and Bissonnet St, for prescription refills, flu shots, COVID-19 vaccines, and walk-in vaccines close to home.
Randalls Pharmacy in Houston also offers everyday pharmacy services including medication reviews, pet prescriptions, blood pressure support, diabetes consultations, and health screenings, making it easier to take care of your health in one convenient stop.
Randalls Pharmacy offers many immunizations for children 3 years and older, teens, and adults, including flu, COVID-19, shingles, pneumonia, RSV, and back-to-school vaccines.
You can also manage prescriptions and schedule vaccines in the Randalls app. With most insurance plans accepted, Randalls Pharmacy is a convenient option for pharmacy care in Houston.
Flu/Influenza is a contagious respiratory illness that effects the nose, throat and lungs. Some people with certain health conditions are at higher risk of flu complications.
The best way to reduce the risk of flu and its potentially serious complications is by getting vaccinated each year.
COVID-19 Vaccine
COVID-19 vaccines play a crucial role in providing protection against the virus. Although breakthrough infections can still occur among vaccinated individuals, staying updated with COVID-19 vaccines significantly reduces the risk of severe illness, hospitalization, or death from COVID-19. The CDC recommends vaccination or booster shots for everyone who is eligible. By following vaccination guidelines, individuals can help protect themselves and reduce the overall impact of COVID-19 in their communities.
Hep B Vaccine
Hepatitis B is a liver infection caused by the hepatitis B virus (HBV) and can be prevented through vaccination. This virus spreads when the blood, semen, or other bodily fluids of an infected person enter the body of an uninfected individual. Transmission can occur through sexual contact, sharing of needles or other drug-injection equipment, or from an infected mother to her baby during childbirth.
Hepatitis B has the potential to develop into a chronic, long-term infection, which can result in serious and even life-threatening health complications such as cirrhosis or liver cancer. The most effective method of preventing hepatitis B is by receiving the hepatitis B vaccine.
HPV Vaccine
Human papillomavirus (HPV) is a common virus that can lead to the development of certain cancers later in life. To protect your child from these potential cancers, it is recommended to administer the HPV vaccine when they are 11 to 12 years old. HPV is primarily transmitted through intimate skin-to-skin contact, including vaginal, anal, or oral sex with an infected individual, even if they do not exhibit any signs or symptoms.
It is recommended that everyone up to the age of 26 receives the HPV vaccine if they have not been fully vaccinated before. However, HPV vaccination is not generally recommended for individuals older than 26 years of age. By following these guidelines, individuals can take important steps to protect themselves from the potential risks associated with HPV-related cancers.
Shingles Vaccine
Shingles is a painful skin rash that emerges on either side of the face or body. This rash is characterized by the formation of blisters, which typically crust over within 7 to 10 days and completely heal within 2 to 4 weeks. When shingles affects the face, it can potentially impact the eye and lead to vision impairment. In rare instances, particularly in individuals with compromised immune systems, the rash may extend more widely across the body and resemble the rash associated with chickenpox.
To prevent shingles and its associated complications in adults aged 50 and above, the Centers for Disease Control and Prevention (CDC) recommends the administration of two doses of recombinant zoster vaccine (RZV), known as Shingrix. Additionally, adults aged 19 and older with weakened immune systems resulting from either illness or treatment are also advised to receive the Shingrix vaccine.
Cholera Vaccine
The cholera vaccine used in the United States is an oral (swallowed) vaccine. Only one dose is needed. Booster doses are not recommended at this time.
Most travelers do not need cholera vaccine. If you are an adult 18 through 64 years old traveling to an area where people are getting infected with cholera, your health care provider might recommend the vaccine for you.
Cholera vaccine is not 100% effective against cholera and does not protect from other foodborne or waterborne diseases. Cholera vaccine is not a substitute for being careful about what you eat or drink.
Source: CDC
Hib Vaccine
Hib vaccine is usually given in 3 or 4 doses (depending on brand).
Infants will usually get their first dose of Hib vaccine at 2 months of age and will usually complete the series at 12–15 months of age.
Hib vaccine may be given as a stand-alone vaccine, or as part of a combination vaccine (a type of vaccine that combines more than one vaccine together into one shot).
Hib vaccine may be given at the same time as other vaccines.
Source: CDC
Hep A Vaccine
Children need 2 doses of hepatitis A vaccine:
First dose: 12 through 23 months of age
Second dose: at least 6 months after the first dose
Infants 6 through 11 months old traveling outside the United States when protection against hepatitis A is recommended should receive 1 dose of hepatitis A vaccine. These children should still get 2 additional doses at the recommended ages for long-lasting protection.
Older children and adolescents 2 through 18 years of age who were not vaccinated previously should be vaccinated.
Adults who were not vaccinated previously and want to be protected against hepatitis A can also get the vaccine.
Source: CDC
Japanese Encephalitis Vaccine
Japanese encephalitis vaccine is approved for people 2 months of age and older.
It is recommended for people who: Plan to live in a country where JE occurs, Plan to visit a country where JE occurs for long periods (e.g., one month or more), or frequently travel to countries where JE occurs.
It should also be considered for travelers spending less than one month in a country where JE occurs, if they will visit rural areas and have an increased risk for mosquito bites or are not sure of their travel plans.
Source: CDC
Measles/Mumps/Rubella (MMR) Vaccine
CDC recommends all children get two doses of MMR (measles-mumps-rubella) vaccine, starting with the first dose at 12 through 15 months of age, and the second dose at 4 through 6 years of age. Children can receive the second dose earlier as long as it is at least 28 days after the first dose.
Source: CDC
Meningococcal Vaccine
Meningococcal ACWY vaccine can help protect against meningococcal disease caused by serogroups A, C, W, and Y. A different meningococcal vaccine is available that can help protect against serogroup B.
Source: CDC
Pneumococcal Conjugate Vaccine
Pneumococcal conjugate vaccine helps protect against bacteria that cause pneumococcal disease. There are three pneumococcal conjugate vaccines (PCV13, PCV15, and PCV20). The different vaccines are recommended for different people based on age and medical status. Your health care provider can help you determine which type of pneumococcal conjugate vaccine, and how many doses, you should receive.
Source: CDC
Pneumococcal Polysaccharide Vaccine
PPSV23 protects against 23 types of bacteria that cause pneumococcal disease. Most people need only one dose of PPSV23. A second dose of PPSV23, and another type of pneumococcal vaccine called PCV13, are recommended for certain high-risk groups. Your health care provider can give you more information.
Source: CDC
Polio (IPV) Vaccine
Children should usually get 4 doses of polio vaccine at ages 2 months, 4 months, 6–18 months, and 4–6 years.
Most adults do not need polio vaccine because they were already vaccinated against polio as children. Some adults are at higher risk and should consider polio vaccination.
Source: CDC
Rabies Vaccine
Rabies vaccine can prevent rabies if given to a person after an exposure. After an exposure or potential exposure to rabies, the wound site should be thoroughly cleaned with soap and water. If your health care provider or local health department recommend vaccination, the vaccine should be given as soon as possible after an exposure but may be effective any time before symptoms begin. Once symptoms begin, rabies vaccine is no longer helpful in preventing rabies.
Source: CDC
Tetanus/Diptheria (Td) Vaccine
Td is only for children 7 years and older, adolescents, and adults.
Td is usually given as a booster dose every 10 years, or after 5 years in the case of a severe or dirty wound or burn.
Source: CDC
Tetanus/Diptheria/Pertussis (Tdap) Vaccine
Tdap is only for children 7 years and older, adolescents, and adults.
Adolescents should receive a single dose of Tdap, preferably at age 11 or 12 years.
Source: CDC
Tickborne Encephalitis Vaccine
The risk for TBE is very low for most travelers visiting countries where TBE is found. However, travelers are at increased risk if they plan to: Visit areas with TBE when ticks are most active (April through November) or take part in outdoor activities in or near forested areas such as hiking, camping, hunting, fishing, or birdwatching.
Source: CDC
Typhoid Vaccine
There are two vaccines to prevent typhoid fever. One is an inactivated (killed) vaccine and the other is a live, attenuated (weakened) vaccine. Your health care provider can help you decide which type of typhoid vaccine is best for you.
Source: CDC
Varicella (VAR)/Chickenpox Vaccine
Children need 2 doses of varicella vaccine, usually:
First dose: age 12 through 15 months
Second dose: age 4 through 6 years
Older children, adolescents, and adults also need 2 doses of varicella vaccine if they are not already immune to chickenpox.
Source: CDC
Reviews
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Julia Zamora
Jun 23, 2026
5.0
I am saddened to read the negative reviews of my Randall’s Pharmacy. Over the past 15 years I have experienced nothing less than excellent service. The staff is friendly and efficient. I have never been disappointed.
FH
Frankie Holmes
Oct 25, 2019
5.0
Yesterday I went to pick up a prescription for my husband at the Randall's Weslyan, Houston, TX Pharmacy. Erroneously, the prescriber had prescribed a medication to which my husband was allergic. Lynn Lassiter, RPh, the pharmacist, alerted me to this. While I and slightly waited for the doctor to call in a new prescription, I sat in the pharmacy area where the Influenza vaccination is administered. An elderly and somewhat frail-appearing black man was waiting for his injection and his healthy wife (or perhaps his adult daughter) were sitting next to me. The gent voiced an "Ouch" during the injection but then stood to leave. He seemed a bit unsteady so his wife/daughter stood by to support him. Immediately, Lynn Lassiter, RPh, was out from behind the counter and standing next to him asking if he felt dizzy, or needed to sit down. He seemed a bit concerned about creating a fuss and declined any help. Lynn Lassiter noted that his shoelaces were untied so she immediately knelt down to tie them for him. He thanked her and said he felt ok. As he walked away, his slow and shuffling gait suggested he was somewhat balance and impaired with walking.
After about 50 minutes, the prescriber called in a prescription that the Randall's Weslyan Pharmacy did not have. So Lynn Lassiter called the Walgreen's next door, the 2 Randalls nearby--one in Houston, one in Bellaire, but none carried the drug. Finally, she discovered the HEB at Bissonnet and Buffalo Speedway did have the drug and transferred the prescription.
During this entire time, she was pleasant and greeted each person warmly. I want to commend Lynn Lassiter, RPh, and Randall's Pharmacy for the high standards of their pharmacy staff at their store
Frequently Asked Questions About Randalls Pharmacy
Does Randalls Pharmacy offer vaccinations, and which ones are available?
Yes! Randalls Pharmacy provides a wide range of vaccinations for children, teens, and adults. Popular vaccines available include pneumonia, flu (influenza), COVID-19, shingles (Shingrix), and Tdap. Whether you need a routine immunization, a back-to-school shot, or a travel vaccine, Randalls Pharmacy makes it easy with walk-in availability and online appointment scheduling. Visit Randalls Pharmacy for convenient and reliable vaccination services near you.
Who should get the shingles shot?
Randalls Pharmacy offers the Shingrix shingles vaccine for adults aged 50 and older, as well as for adults 19 and older with weakened immune systems. The CDC recommends two doses, spaced 2 to 6 months apart, to protect against shingles and its complications. You can get vaccinated at Randalls Pharmacy even if you've had shingles before, received the Zostavax vaccine, or are unsure if you had chickenpox.
Does Randalls Pharmacy require an appointment for a vaccination?
No, Randalls Pharmacy does not require an appointment for vaccinations. Walk-ins are welcome, making it easy and convenient to get vaccinated on your schedule.
Why is reviewing my Medicare plan every year important?
Reviewing your Medicare plan every year is important because Medicare Advantage (Part C) and Medicare Prescription Drug Plans (Part D) can change annually. These changes may affect your coverage, out-of-pocket costs, and provider network. By reviewing your plan during the Medicare Annual Enrollment Period, you can ensure it still meets your healthcare needs and budget—and switch plans if necessary.
What types of vaccinations does Randalls Pharmacy offer?
Randalls Pharmacy offers various vaccinations including pneumonia, flu, COVID-19, shingles (Shingrix), Tdap, travel vaccines, and back-to-school immunizations. Walk-ins and online appointments are available.
Is an appointment required for vaccinations at Randalls Pharmacy?
No, Randalls Pharmacy welcomes walk-ins for vaccinations, so you can get vaccinated without an appointment.
Who is eligible for the shingles vaccine at Randalls Pharmacy?
The shingles vaccine (Shingrix) is recommended for adults aged 50 and older and adults 19 and older with weakened immune systems. Two doses spaced 2 to 6 months apart are advised.
How can I transfer my prescription to Randalls Pharmacy at 5586 Weslayan St?
You can transfer prescriptions easily by visiting the Randalls Prescription Transfer online page and completing the required fields.
What are the opening hours of Randalls Pharmacy on weekends?
The pharmacy is open from 9:00 AM to 6:00 PM on Saturdays and from 10:00 AM to 5:00 PM on Sundays.
Does Randalls Pharmacy accept multiple payment options?
Yes, Randalls accepts various payment methods including American Express, Apple Pay, Visa, Mastercard, cash, and more.
Where is Randalls Pharmacy located in Houston, TX?
Randalls Pharmacy is located at 5586 Weslayan St, Houston, TX 77005, USA.
What nearby places can I visit before or after visiting Randalls Pharmacy?
Nearby you can find Randalls supermarket, Wells Fargo Bank, Cold Stone Creamery for ice cream, ZENSHI Handcrafted Sushi restaurant, and Pearl 32 Dentistry, among others.
Are there other pharmacies near Randalls Pharmacy where I can pick up prescriptions?
Yes, Walgreens pharmacy is located nearby, providing additional options for prescription pickup and pharmacy services.
How can nearby fitness centers complement my visit to Randalls Pharmacy?
After visiting Randalls Pharmacy, you might consider visiting nearby gyms like Row Studios or P3 Houston to support your health and wellness goals.
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