H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 2300 N. Shepherd Drive in Houston, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
Thanks to Juliana for the wine tasting and info on the wine. 🤘🏼
DT
Deborah Tovar
Apr 30, 2026
5.0
I’ve been coming to this pharmacy for quite some time now but most recently I’ve had issues with insurance requiring pre auth for my insulin (sadly I need this or I could die). I’ve been a type 1 diabetic for more than 27 years and have never had issues with getting my medication. Ismael, the pharmacist, along with other members of the team played a huge part in getting my insulin ASAP! Thank you so much for your hard work. I am beyond grateful :)
DR
David Rivera
Apr 26, 2026
5.0
Huge place with lots of options.
LR
Ladajia Robins
Apr 8, 2026
5.0
Ishmael was a great help! He was very thorough in explaining everything and helped me resolve my issue.
AC
Abhijnan Chattopadhyay
Apr 5, 2026
1.0
The staff are really nice and helpful but their app is terrible. Since I transferred my prescriptions from CVS to HEB nearly 3 months ago, despite enrolling auto-refill, I have had to request refills manually each time. Their staff completed the refills very quickly (for which I appreciate them), but what is then the point of enrolling in auto-refill? I needed an approval from my physician for a medication (my insurance only approves it 28 days following a pickup) and I requested it on the correct date; despite being told on the app that they’re contacting my provider, my current status on the app showed “request refill” which I had to do again this morning. Based on the response from the app, it seems it’ll take 3 additional days, which means I won’t be able to take that weekly medication on time this week, like it has been the case on a previous occasion. I have never had this problem with CVS when I used them for nearly 18 months. I’m strongly considering transferring to a different pharmacy.
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours of the H-E-B Pharmacy at 2300 N. Shepherd Drive?
The pharmacy is open Monday to Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy accept walk-in customers for COVID-19 and flu vaccines?
Yes, H-E-B Pharmacy offers COVID-19 and flu vaccines on both a walk-in and appointment basis.
Where can I find the latest information about COVID-19 vaccines at H-E-B Pharmacy?
You can visit https://vaccine.heb.com/ for the latest vaccine information, including current phases and FAQs.
What payment options are accepted at H-E-B Pharmacy?
H-E-B Pharmacy accepts American Express, Android Pay, Apple Pay, cash, check, contactless payment, Discover, Mastercard, Samsung Pay, and Visa.
Does H-E-B Pharmacy offer delivery services?
Yes, delivery is available for pharmacy orders.
Is H-E-B Pharmacy wheelchair accessible and do they have accessible parking?
Yes, the pharmacy has wheelchair accessible parking and is accessible for customers with disabilities.
Which nearby places can I visit near H-E-B Pharmacy at 2300 N. Shepherd Drive?
Nearby places include H-E-B supermarket and grocery store, Mico’s Hot Chicken restaurant, Memorial Hermann GoHealth Urgent Care, and Blue Rhino Propane Exchange.
Are there fitness centers close to H-E-B Pharmacy for customers interested in health activities?
Yes, nearby fitness options include Studio Fitness, Facet Seven Heights gym, Digg Deep Fitness and Nutrition, and 9AM Girl Power by Rig Dog CrossFit.
What dining options are available near H-E-B Pharmacy?
Customers can enjoy nearby restaurants like Taqueria Don Tin (Mexican cuisine), Copper Penny (Chinese restaurant), and Pipers Burger (burger and barbecue).
Is there an ATM available near H-E-B Pharmacy for convenient cash withdrawals?
Yes, there are several ATMs nearby including HEB ATM, Coinme, Coin Cloud Bitcoin ATM, and The Exchange Network.
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