Narrowing of the carotid artery, one of the main arteries supplying blood flow to the brain, by plaque can lead to increased risk of TIAs and stroke and may result in small pieces of plaque breaking off and flowing into and blocking a major blood vessel in the brain. Angioplasty and stenting may be used in combination with thrombectomy to allow passage of the thrombectomy device into the brain in cases where the narrowing of the artery is too severe. The interventional radiologist can treat narrowing of the carotid artery by using a balloon to widen the artery followed by placement of a stent (a tiny mesh tube) to keep the artery open and prevent narrowing from redeveloping. The carotid arteries are the main vessels supplying blood to the brain. Most individuals have one carotid artery on each side of the neck. The carotid arteries can become narrowed (stenosed) by atherosclerosis and fatty or calcified plaque, resulting in diminished blood flow to the brain. The brain has some ability to compensate for some degree of decreased blood flow, but if flow becomes decreased to a point that the blood vessels and brain tissue can no longer compensate for the decreased blood flow caused by the blockage, death of brain tissue can occur leading to a stroke. Stroke is the 2nd leading cause of death and 4th leading cause of disability worldwide. While in developed countries it is the leading cause of disability, 2nd leading cause of dementia, and 3rd leading cause of death 50% of survivors suffer permanent disability Carotid stenosis account for 25-30% of strokes Repair of blockage is typically recommended in patients with 70% blockage or greater and experiencing symptoms such as weakness, dizziness, or visual changes. While somewhat more controversial, most physicians will recommend repair in asymptomatic individuals with greater than 80% blockage While traditional surgical repair of carotid blockage remains the preferred method of repair of carotid blockage in many individuals, carotid artery angioplasty and stenting has assumed a greater role in treatment of the disease, particularly in individuals who have increased risk with surgery or associated anesthesia or may have some unusual anatomy scarring from prior surgery that would increase the risks associated with the traditional surgical approach. In carotid angioplasty, a small needle is placed into the artery at the top of the leg and a tiny angioplasty balloon attached to a plastic catheter is advanced under X-ray guidance to the level of the blockage in the carotid artery. The balloon is inflated for a short period of time. After the dilation, a second small catheter with a self-expanding stent is advanced to the blockage and deployed. Risks associated with carotid stenting are considered similar to those associated with traditional surgery in the normal population and often decreased in those patients considered higher risk for surgery. To further prevent the risk of a small piece of plaque from breaking loose and reaching the brain, a special filter is placed above the blockage in the artery to trap any debris. Post procedure hospital stay is limited, typically one evening. Patients may resume normal daily activities nearly immediately and are typically maintained on mild blood-thinning medications like aspirin or Plavix for a number of months post procedure to further decrease risk of any clot formation following treatment.