Need a pharmacy in Downers Grove, IL? Visit Jewel-Osco Pharmacy at 6215 Main St, near the intersection of Main St and 63rd St, for prescription refills, flu shots, COVID-19 vaccines, and walk-in vaccines close to home.
Jewel-Osco Pharmacy in Downers Grove also offers everyday pharmacy services including medication reviews, pet prescriptions, blood pressure support, diabetes consultations, and health screenings, making it easier to take care of your health in one convenient stop.
Jewel-Osco Pharmacy offers many immunizations for children 3 years and older, teens, and adults, including flu, COVID-19, shingles, pneumonia, RSV, and back-to-school vaccines.
You can also manage prescriptions and schedule vaccines in the Jewel-Osco app. With most insurance plans accepted, Jewel-Osco Pharmacy is a convenient option for pharmacy care in Downers Grove.
Explore offerings from Jewel-Osco Pharmacy on 6215 Main St in Downers Grove, with popular vaccinations & immunizations available at this location.
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Vaccinations & Immunizations
Flu Shots
Flu/Influenza is a contagious respiratory illness that effects the nose, throat and lungs. Some people with certain health conditions are at higher risk of flu complications.
The best way to reduce the risk of flu and its potentially serious complications is by getting vaccinated each year.
COVID-19 Vaccine
COVID-19 vaccines play a crucial role in providing protection against the virus. Although breakthrough infections can still occur among vaccinated individuals, staying updated with COVID-19 vaccines significantly reduces the risk of severe illness, hospitalization, or death from COVID-19. The CDC recommends vaccination or booster shots for everyone who is eligible. By following vaccination guidelines, individuals can help protect themselves and reduce the overall impact of COVID-19 in their communities.
Hep B Vaccine
Hepatitis B is a liver infection caused by the hepatitis B virus (HBV) and can be prevented through vaccination. This virus spreads when the blood, semen, or other bodily fluids of an infected person enter the body of an uninfected individual. Transmission can occur through sexual contact, sharing of needles or other drug-injection equipment, or from an infected mother to her baby during childbirth.
Hepatitis B has the potential to develop into a chronic, long-term infection, which can result in serious and even life-threatening health complications such as cirrhosis or liver cancer. The most effective method of preventing hepatitis B is by receiving the hepatitis B vaccine.
HPV Vaccine
Human papillomavirus (HPV) is a common virus that can lead to the development of certain cancers later in life. To protect your child from these potential cancers, it is recommended to administer the HPV vaccine when they are 11 to 12 years old. HPV is primarily transmitted through intimate skin-to-skin contact, including vaginal, anal, or oral sex with an infected individual, even if they do not exhibit any signs or symptoms.
It is recommended that everyone up to the age of 26 receives the HPV vaccine if they have not been fully vaccinated before. However, HPV vaccination is not generally recommended for individuals older than 26 years of age. By following these guidelines, individuals can take important steps to protect themselves from the potential risks associated with HPV-related cancers.
Shingles Vaccine
Shingles is a painful skin rash that emerges on either side of the face or body. This rash is characterized by the formation of blisters, which typically crust over within 7 to 10 days and completely heal within 2 to 4 weeks. When shingles affects the face, it can potentially impact the eye and lead to vision impairment. In rare instances, particularly in individuals with compromised immune systems, the rash may extend more widely across the body and resemble the rash associated with chickenpox.
To prevent shingles and its associated complications in adults aged 50 and above, the Centers for Disease Control and Prevention (CDC) recommends the administration of two doses of recombinant zoster vaccine (RZV), known as Shingrix. Additionally, adults aged 19 and older with weakened immune systems resulting from either illness or treatment are also advised to receive the Shingrix vaccine.
Cholera Vaccine
The cholera vaccine used in the United States is an oral (swallowed) vaccine. Only one dose is needed. Booster doses are not recommended at this time.
Most travelers do not need cholera vaccine. If you are an adult 18 through 64 years old traveling to an area where people are getting infected with cholera, your health care provider might recommend the vaccine for you.
Cholera vaccine is not 100% effective against cholera and does not protect from other foodborne or waterborne diseases. Cholera vaccine is not a substitute for being careful about what you eat or drink.
Source: CDC
Hib Vaccine
Hib vaccine is usually given in 3 or 4 doses (depending on brand).
Infants will usually get their first dose of Hib vaccine at 2 months of age and will usually complete the series at 12–15 months of age.
Hib vaccine may be given as a stand-alone vaccine, or as part of a combination vaccine (a type of vaccine that combines more than one vaccine together into one shot).
Hib vaccine may be given at the same time as other vaccines.
Source: CDC
Hep A Vaccine
Children need 2 doses of hepatitis A vaccine:
First dose: 12 through 23 months of age
Second dose: at least 6 months after the first dose
Infants 6 through 11 months old traveling outside the United States when protection against hepatitis A is recommended should receive 1 dose of hepatitis A vaccine. These children should still get 2 additional doses at the recommended ages for long-lasting protection.
Older children and adolescents 2 through 18 years of age who were not vaccinated previously should be vaccinated.
Adults who were not vaccinated previously and want to be protected against hepatitis A can also get the vaccine.
Source: CDC
Japanese Encephalitis Vaccine
Japanese encephalitis vaccine is approved for people 2 months of age and older.
It is recommended for people who: Plan to live in a country where JE occurs, Plan to visit a country where JE occurs for long periods (e.g., one month or more), or frequently travel to countries where JE occurs.
It should also be considered for travelers spending less than one month in a country where JE occurs, if they will visit rural areas and have an increased risk for mosquito bites or are not sure of their travel plans.
Source: CDC
Measles/Mumps/Rubella (MMR) Vaccine
CDC recommends all children get two doses of MMR (measles-mumps-rubella) vaccine, starting with the first dose at 12 through 15 months of age, and the second dose at 4 through 6 years of age. Children can receive the second dose earlier as long as it is at least 28 days after the first dose.
Source: CDC
Meningococcal Vaccine
Meningococcal ACWY vaccine can help protect against meningococcal disease caused by serogroups A, C, W, and Y. A different meningococcal vaccine is available that can help protect against serogroup B.
Source: CDC
Pneumococcal Conjugate Vaccine
Pneumococcal conjugate vaccine helps protect against bacteria that cause pneumococcal disease. There are three pneumococcal conjugate vaccines (PCV13, PCV15, and PCV20). The different vaccines are recommended for different people based on age and medical status. Your health care provider can help you determine which type of pneumococcal conjugate vaccine, and how many doses, you should receive.
Source: CDC
Pneumococcal Polysaccharide Vaccine
PPSV23 protects against 23 types of bacteria that cause pneumococcal disease. Most people need only one dose of PPSV23. A second dose of PPSV23, and another type of pneumococcal vaccine called PCV13, are recommended for certain high-risk groups. Your health care provider can give you more information.
Source: CDC
Polio (IPV) Vaccine
Children should usually get 4 doses of polio vaccine at ages 2 months, 4 months, 6–18 months, and 4–6 years.
Most adults do not need polio vaccine because they were already vaccinated against polio as children. Some adults are at higher risk and should consider polio vaccination.
Source: CDC
Rabies Vaccine
Rabies vaccine can prevent rabies if given to a person after an exposure. After an exposure or potential exposure to rabies, the wound site should be thoroughly cleaned with soap and water. If your health care provider or local health department recommend vaccination, the vaccine should be given as soon as possible after an exposure but may be effective any time before symptoms begin. Once symptoms begin, rabies vaccine is no longer helpful in preventing rabies.
Source: CDC
Tetanus/Diptheria (Td) Vaccine
Td is only for children 7 years and older, adolescents, and adults.
Td is usually given as a booster dose every 10 years, or after 5 years in the case of a severe or dirty wound or burn.
Source: CDC
Tetanus/Diptheria/Pertussis (Tdap) Vaccine
Tdap is only for children 7 years and older, adolescents, and adults.
Adolescents should receive a single dose of Tdap, preferably at age 11 or 12 years.
Source: CDC
Tickborne Encephalitis Vaccine
The risk for TBE is very low for most travelers visiting countries where TBE is found. However, travelers are at increased risk if they plan to: Visit areas with TBE when ticks are most active (April through November) or take part in outdoor activities in or near forested areas such as hiking, camping, hunting, fishing, or birdwatching.
Source: CDC
Typhoid Vaccine
There are two vaccines to prevent typhoid fever. One is an inactivated (killed) vaccine and the other is a live, attenuated (weakened) vaccine. Your health care provider can help you decide which type of typhoid vaccine is best for you.
Source: CDC
Varicella (VAR)/Chickenpox Vaccine
Children need 2 doses of varicella vaccine, usually:
First dose: age 12 through 15 months
Second dose: age 4 through 6 years
Older children, adolescents, and adults also need 2 doses of varicella vaccine if they are not already immune to chickenpox.
Source: CDC
Yellow Fever Vaccine
Yellow fever vaccine is a live vaccine containing weakened, live yellow fever virus. It is given as a single shot. One dose provides lifelong protection for most people.
Source: CDC
Reviews
3.5
31 reviews
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JC
John Coleman
Apr 14, 2026
1.0
This App is worthless. I can no longer see my prescriptions. I’ve rebooted this multiple times
MC
Maggi Cardenas
Apr 4, 2026
5.0
Never had a line and great customer service
PS
Pamela Stella
Dec 11, 2025
2.0
Picked up prescription today with quite a wait cause all the staff were working on filling prescriptions. Not a very pleasant approach either. Not customer friendly
JJ
Jeff
Aug 26, 2024
1.0
Although I would prefer to leave zero stars, my review comments are similar to those that others have left. A callout to the actual pharmacists- they are quite helpful, and of course knowledgeable and have the requisite service skills. The real negative is with the techs that have zero service skills and fall short on the technical skills. Said differently-essentially useless and talk in circles. It's not clear to me if 1) they do not care (clock punching attitude), 2) they do not appreciate the significance of their role, and/or 3) are not receiving/comprehending the job specific training that I am certain Osco would mandate.
Avoid this location if you are seeking a customer focused experience.
Thanks for reading
CB
Cou Berry
Jun 8, 2019
1.0
TLDR: Don’t go to this store, terrible staff and clear managerial problems.
It is far past my limit of second tries with this store, but today has cemented my decision to never return to this location again. I was screamed at, by what I assume was the manager, for waiting at the customer service desk to ask someone if I could buy an I-pass here. I was completely ignored and was rudely talked down to by Kimberly at the register while she was having a conversation with another co-worker who was behind me in line, buying things on the clock I might add, and then was upset at me that she forgot I asked for yard waste stickers and was very rude to me about needing to re-open her register she slammed shut because she was too focused on her conversation with the person behind me.
I don’t know what is wrong with this store, but this time a mean lady named Karen in the ready to eat food section went after her co-workers with a terrible attitude and poor behavior. She was snippy, short tempered and looked annoyed at them for asking her a question for me. I asked Cederyck if there was any way they could make me a few chicken tenders since they didn’t have any ready. He then went to ask Karen for me. Karen was talking to a friend while “cleaning” and looked like she was ready to pop a blood vessel for being interrupted. She stormed away from her conversation and all but screamed “what is it?” Cederyck asked, “could I put on some chicken tenders for this miss?” She looked at the case dumbfounded and then said, in a very ill tempered voice, “Do... you.... SEE any chicken tenders down here!?!!” He shyly responded, “no...” and before he could finish she burst in with, “THEN NO, WE DONT HAVE ANY!!!” And immediately stormed around the area to go back to her conversation with the random other lady. Another co-worker asked her a question a few moments later and she, again, stormed back and started griping about how she was trying to clean and how her gloves are dirty and they needed to stop bothering her for every small thing like this, all in very rude and demeaning tones.
Kimberly was her normal terrible self and wasn’t pleasant to deal with. I don’t speak to her unless she asks me a question because I don’t want to hear her get mad at me again. This time, however, she was screaming at a new worker named Caleb and telling him he was bad at his job. She stood there talking down to him, being rude to him and was annoyed that I was nice to him. She stood there the whole time being sour and rude and even though Caleb was still helping the previous guest she decided to yell at him for not focusing on bagging my order when she clearly had nothing better to do. She uttered that he was the reason her line was moving so slow.
I can handle being talked down to and I learn easily who to avoid at places if that aren’t welcoming, but these two women were clearly bullying, picking on and treating the new workers very poorly and it is just disgusting how awful their behavior was to them. These poor people have to work with these hostile attitudes and no work place should ever accept this kind of awful treatment of their workers.
I would complain to their Manager about these people’s bad behavior, but they are always hidden away in their tiny fort near the customer service desk. This is the closest grocery store to me, but I will not be returning here again.
Frequently Asked Questions About Jewel-Osco Pharmacy
Does Jewel-Osco Pharmacy located at 6215 Main St, Downers Grove, IL offer vaccinations, and which ones are available?
Yes! Jewel-Osco Pharmacy provides a wide range of vaccinations for children, teens, and adults. Popular vaccines available include pneumonia, flu (influenza), COVID-19, shingles (Shingrix), and Tdap. Whether you need a routine immunization, a back-to-school shot, or a travel vaccine, Jewel-Osco Pharmacy makes it easy with walk-in availability and online appointment scheduling. Visit Jewel-Osco Pharmacy for convenient and reliable vaccination services near you.
Who should get the shingles shot?
Jewel-Osco Pharmacy offers the Shingrix shingles vaccine for adults aged 50 and older, as well as for adults 19 and older with weakened immune systems. The CDC recommends two doses, spaced 2 to 6 months apart, to protect against shingles and its complications. You can get vaccinated at Jewel-Osco Pharmacy even if you've had shingles before, received the Zostavax vaccine, or are unsure if you had chickenpox.
Does Jewel-Osco Pharmacy require an appointment for a vaccination?
No, Jewel-Osco Pharmacy does not require an appointment for vaccinations. Walk-ins are welcome, making it easy and convenient to get vaccinated on your schedule.
Why is reviewing my Medicare plan every year important?
Reviewing your Medicare plan every year is important because Medicare Advantage (Part C) and Medicare Prescription Drug Plans (Part D) can change annually. These changes may affect your coverage, out-of-pocket costs, and provider network. By reviewing your plan during the Medicare Annual Enrollment Period, you can ensure it still meets your healthcare needs and budget—and switch plans if necessary.
What are the hours of operation for Jewel-Osco Pharmacy in Downers Grove?
Jewel-Osco Pharmacy is open Monday to Friday from 8:00 AM to 10:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 9:00 AM to 5:00 PM. Note that holiday hours may vary.
Does Jewel-Osco Pharmacy require appointments for COVID-19 vaccinations or testing?
No appointments are required for COVID-19 vaccinations or testing at Jewel-Osco Pharmacy; walk-ins are welcome.
Which vaccinations are available at Jewel-Osco Pharmacy?
Jewel-Osco offers a variety of vaccinations including flu, pneumonia, shingles (Shingrix), Tdap, COVID-19, travel vaccines, and back-to-school shots for children, teens, and adults.
Who is eligible for the shingles vaccine at Jewel-Osco Pharmacy?
Adults aged 50 and older, as well as adults 19 and older with weakened immune systems, are eligible for the Shingrix shingles vaccine at Jewel-Osco Pharmacy.
What pharmacy services does Jewel-Osco offer beyond vaccinations?
Services include prescription transfer and filling, medication reviews, blood pressure monitoring, diabetes consultations, specialty pharmacy, travel health, worker's comp, and delivery options including same-day and business delivery.
Which payment methods does Jewel-Osco Pharmacy accept?
Jewel-Osco Pharmacy accepts American Express, Android Pay, Apple Pay, cash, check, Diners Club, Discover, MasterCard, Samsung Pay, Traveler's Check, and Visa.
How can I manage my prescriptions online with Jewel-Osco Pharmacy?
You can easily manage your prescriptions online for free using Jewel-Osco's online Rx management tool available on their website.
Are there nearby places to shop or eat around Jewel-Osco Pharmacy?
Yes, nearby places include the Jewel-Osco grocery store, Teddy's Red Hots restaurant for fast food, and Kin-Ko Ace Stores for retail shopping, offering options before or after your pharmacy visit.
Where can I find financial services near Jewel-Osco Pharmacy?
Nearby financial services include Huntington Bank, Chase Bank, TCF Bank, and Coinme for ATMs and currency exchange, convenient for managing finances during your visit.
What other health-related services are near Jewel-Osco Pharmacy in Downers Grove?
Nearby health-related services include the Animal Care Center of Downers Grove and Downers Grove Animal Clinic for pet care, as well as HearUSA for audiology and hearing aid services.
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