Brand Certified
Safeway Pharmacy
3.2(42 reviews)
Certified by Safeway Pharmacy • May 17, 2026
Business Details
181 W Mineral Ave, Littleton, CO
80120, United States
Certified by Safeway Pharmacy • May 17, 2026
(303) 218-2104
Certified by Safeway Pharmacy • May 17, 2026
https://local.pharmacy.safeway.com/safeway/co/littleton/181-w-mineral-ave.html
Certified by Safeway Pharmacy • May 17, 2026
About
Certified by Safeway Pharmacy • May 17, 2026
PharmacyDrug StoreVitamin & Supplements StoreSafeway Pharmacy
Need a pharmacy in Littleton, CO? Visit Safeway Pharmacy at 181 W Mineral Ave for prescription refills, flu shots, COVID-19 vaccines, and walk-in vaccines close to home.
Safeway Pharmacy in Littleton also offers everyday pharmacy services including medication reviews, pet prescriptions, blood pressure support, diabetes consultations, and health screenings, making it easier to take care of your health in one convenient stop.
Looking for vaccines in Littleton? Safeway Pharmacy offers immunizations for children, teens, and adults, including flu, COVID-19, shingles, pneumonia, RSV, and back-to-school vaccines.
You can also manage prescriptions and schedule vaccines in the Safeway app. With most insurance plans accepted, Safeway Pharmacy is a convenient option for pharmacy care in Littleton.
Details
- DeliveryAvailable
- Requires appointmentNot available
- Credit cardAvailable
- DebitAvailable
Location
Certified by Safeway Pharmacy • May 17, 2026
Hours
Certified by Safeway Pharmacy • May 17, 2026
Monday9:00 AM - 1:30 PM2:00 PM - 8:00 PM
Tuesday9:00 AM - 1:30 PM2:00 PM - 8:00 PM
Wednesday9:00 AM - 1:30 PM2:00 PM - 8:00 PM
Thursday9:00 AM - 1:30 PM2:00 PM - 8:00 PM
Friday9:00 AM - 1:30 PM2:00 PM - 8:00 PM
Saturday9:00 AM - 1:30 PM2:00 PM - 5:00 PM
Sunday10:00 AM - 1:30 PM2:00 PM - 5:00 PM
5/25/20269:00 AM - 1:30 PM2:00 PM - 8:00 PM
Reviews
3.2
42 reviews
5 stars
20
4 stars
4
3 stars
1
2 stars0
1 star
17
- SRSarah RadkeMay 13, 20265.0I have always had a good experience with the people working at this pharmacy. They do what they can to get my meds and are good at explaining what to do when there is a delay.
- DRDiane RamirezApr 25, 20265.0I had an idea excellent customer experience with Dianne H. @ the 181 W. Mineral Safeway. Dianne went far beyond the call of duty in assisting with a HORRIBLE INSTACART issue. 1,000 Thanks to you DIANNE H.!!!
- SKSomm Lady's KitchenApr 8, 20261.0Profoundly unhelpful and rude, had my prescriptions transferred will never use Safeways pharmacy going forward.
- BRBryan ReeseMar 10, 20265.0Hello! Several years ago I wrote a bad review for this pharmacy. Well times have changed and I just deleted that review. The crew they have there now is awesome. I really don't know who to give the credit to but they sure do a great job now. And when you are sick and feeling bad, you need a good place to go to get your medicine.
- AAAshleyFeb 27, 20265.0I had such an amazing experience at this pharmacy. I came in already stressed and overwhelmed after leaving Littleton ER and Christina and Shannon were great. I talked to Shannon checking out and immediately made me feel calmer just by the way she spoke to me. She genuinely cared about making sure I left feeling better. In a moment where I really needed someone steady and understanding, she showed up in the best way. Christina was EXTREMELY fast filling my medications that weren't ready yet and made it her priority, and was done in under 5 minutes. These ladies were patient, kind, and never once made me feel rushed or like I was “just another customer.” You can tell they truly care about the people they help. That kind of compassion makes such a difference especially on stressful days. I showed up in tears and left laughing! ❤️ This is definitely my go to pharmacy from here on out, CVS is awful! Keep up the good work ladies!
Frequently Asked Questions About Safeway Pharmacy
Does Safeway Pharmacy offer vaccinations, and which ones are available?
Yes! Safeway Pharmacy provides a wide range of vaccinations for children, teens, and adults. Popular vaccines available include pneumonia, flu (influenza), COVID-19, shingles (Shingrix), and Tdap. Whether you need a routine immunization, a back-to-school shot, or a travel vaccine, Safeway Pharmacy makes it easy with walk-in availability and online appointment scheduling. Visit Safeway Pharmacy for convenient and reliable vaccination services near you.
Who should get the shingles shot?
Safeway Pharmacy offers the Shingrix shingles vaccine for adults aged 50 and older, as well as for adults 19 and older with weakened immune systems. The CDC recommends two doses, spaced 2 to 6 months apart, to protect against shingles and its complications. You can get vaccinated at Safeway Pharmacy even if you've had shingles before, received the Zostavax vaccine, or are unsure if you had chickenpox.
Does Safeway Pharmacy require an appointment for a vaccination?
No, Safeway Pharmacy does not require an appointment for vaccinations. Walk-ins are welcome, making it easy and convenient to get vaccinated on your schedule.
Why is reviewing my Medicare plan every year important?
Reviewing your Medicare plan every year is important because Medicare Advantage (Part C) and Medicare Prescription Drug Plans (Part D) can change annually. These changes may affect your coverage, out-of-pocket costs, and provider network. By reviewing your plan during the Medicare Annual Enrollment Period, you can ensure it still meets your healthcare needs and budget—and switch plans if necessary.
What vaccinations are available at Safeway Pharmacy in Littleton?
Safeway Pharmacy offers a variety of vaccinations including pneumonia, flu, COVID-19, shingles (Shingrix), and Tdap for all ages.
Does Safeway Pharmacy require appointments for vaccinations or COVID-19 testing?
No appointments are required for vaccinations or COVID-19 testing; walk-ins are welcome.
What are the operating hours of Safeway Pharmacy during weekdays and weekends?
Monday to Friday: 9:00 AM - 1:30 PM and 2:00 PM - 8:00 PM; Saturday: 9:00 AM - 1:30 PM and 2:00 PM - 5:00 PM; Sunday: 10:00 AM - 1:30 PM and 2:00 PM - 5:00 PM.
How can I transfer my prescription to Safeway Pharmacy at 181 W Mineral Ave?
You can transfer prescriptions by visiting Safeway's Prescription Transfer website and completing the required information.
Does Safeway Pharmacy offer delivery and in-store pickup options?
Yes, Safeway Pharmacy offers delivery including same-day delivery, as well as in-store pickup services.
What payment methods does Safeway Pharmacy accept?
Safeway Pharmacy accepts American Express, Android Pay, Apple Pay, Cash, Check, Diners Club, Discover, MasterCard, Samsung Pay, Travelers Check, and Visa.
Are there any nearby places where I can grab a coffee before or after visiting Safeway Pharmacy?
Yes, Starbucks and Blend Nutrition, both coffee shops and smoothie bars, are nearby where you can enjoy a drink before or after your pharmacy visit.
What local banking options are available close to Safeway Pharmacy?
Nearby banks include US Bank and U.S. Bank ATM, which may be convenient for your financial needs when visiting the pharmacy.
Are there any fitness or wellness centers near Safeway Pharmacy?
Yes, Sumits Yoga Colorado and FIT/ology Fitness Boutique are nearby facilities where you can pursue yoga and fitness activities along with your pharmacy visit.
Does Safeway Pharmacy provide services for safe medication disposal?
Yes, Safeway Pharmacy features medication disposal bins to help you safely dispose of medications.
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