Need a pharmacy in Mesa, AZ? Visit Safeway Pharmacy at 4316 S Signal Butte Rd for prescription refills, flu shots, COVID-19 vaccines, and walk-in vaccines close to home.
Safeway Pharmacy in Mesa also offers everyday pharmacy services including medication reviews, pet prescriptions, blood pressure support, diabetes consultations, and health screenings, making it easier to take care of your health in one convenient stop.
Looking for vaccines in Mesa? Safeway Pharmacy offers immunizations for children, teens, and adults, including flu, COVID-19, shingles, pneumonia, RSV, and back-to-school vaccines.
You can also manage prescriptions and schedule vaccines in the Safeway app. With most insurance plans accepted, Safeway Pharmacy is a convenient option for pharmacy care in Mesa.
TERRIBLE CUSTOMER SERVICE EVERYTIME from the girl with the BLACK HAIR ! She is ALWAYS RUDE and ALWAYS HAS A BAD ATTITUDE ! She is working today !
EVERYONE ELSE is ALWAYS Very pleasant!
KK
Kaila
Apr 24, 2026
1.0
Richard the pharmacist is very rude and short on the phone. Seemed like he was trying to rush me off of the phone and was unhappy to be speaking with me. As a prescriber I can definitely forsee patients being discouraged to get medications due to the poor service.
CF
Claudia Fairbanks
Feb 16, 2026
5.0
The staff is phenomenal. They work hard to help everyone as quickly as possible. They close daily for lunch, so plan accordingly. If you have questions about your prescriptions call and they will help.
VS
Vie Soldis
Jan 20, 2026
5.0
I love there's a drive-up window to pickup your prescription. Super clean, lots of choices, friendly staff.
Does Safeway Pharmacy offer vaccinations, and which ones are available?
Yes! Safeway Pharmacy provides a wide range of vaccinations for children, teens, and adults. Popular vaccines available include pneumonia, flu (influenza), COVID-19, shingles (Shingrix), and Tdap. Whether you need a routine immunization, a back-to-school shot, or a travel vaccine, Safeway Pharmacy makes it easy with walk-in availability and online appointment scheduling. Visit Safeway Pharmacy for convenient and reliable vaccination services near you.
Who should get the shingles shot?
Safeway Pharmacy offers the Shingrix shingles vaccine for adults aged 50 and older, as well as for adults 19 and older with weakened immune systems. The CDC recommends two doses, spaced 2 to 6 months apart, to protect against shingles and its complications. You can get vaccinated at Safeway Pharmacy even if you've had shingles before, received the Zostavax vaccine, or are unsure if you had chickenpox.
Does Safeway Pharmacy require an appointment for a vaccination?
No, Safeway Pharmacy does not require an appointment for vaccinations. Walk-ins are welcome, making it easy and convenient to get vaccinated on your schedule.
Why is reviewing my Medicare plan every year important?
Reviewing your Medicare plan every year is important because Medicare Advantage (Part C) and Medicare Prescription Drug Plans (Part D) can change annually. These changes may affect your coverage, out-of-pocket costs, and provider network. By reviewing your plan during the Medicare Annual Enrollment Period, you can ensure it still meets your healthcare needs and budget—and switch plans if necessary.
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