H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 3540 Rayford Rd in Spring, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
I used to love filling my medications at H-E-B. They were always great about filling prescriptions quickly and keeping the medications I need in stock.
Both my husband and I are disabled, and we both see a pain management doctor. Our prescriptions come from the same doctor and never change. H-E-B had no problem filling them for an entire year until one day they suddenly decided they would no longer fill our pain prescriptions because our pain doctor wasn’t located in the Spring area.
This left us in a difficult situation because we had to find a new pharmacy, and the other pharmacies refused to take over our prescriptions after seeing that H-E-B had previously been filling them for so long.
The pharmacy manager was quite rude about the situation, and I still don’t understand how they could abruptly refuse to fill prescriptions they had been filling without issue for the entire previous year. I would understand if they refused from the gecko, but they had absolutely no issue with it until one day they did. I really wish they would reconsider because they are such a convenient pharmacy for us especially with the severe medical issues my husband and I have.
NS
Nick Sereno
Feb 20, 2026
5.0
I loved this HEB. Isles were very spacious and organized. The H-E-B partners work very fast and have great energy. Restrooms were pretty clean as well, just wish there were air fresheners inside each stall. On a Friday, the parking lot was very full. I don’t think I’ve ever had to take this long to find parking at any HEB, even ones that have small parking lots. I’m usually towing a trailer every time we go to HEB so this very busy parking lot was a challenge. HOWEVER, even though the parking lot was full, there wasn’t too many customers inside HEB which I liked so I could be in and out :)
JR
James Rowe
Feb 10, 2026
1.0
Medicine is on back order.. i wait and wait. I call to check up and I'm no longer in queue for my order. Was told that they don't go with next in line.. they just pick people to fill at random for anyone waiting. It's 2025.. there has to be a better way by now..
LM
Leo Muntaniol
Feb 4, 2026
5.0
Love my H-E-B !
LZ
Lilia Esther Zeman
Dec 22, 2025
1.0
This is the worse Pharmacy service I ever had in my entire life their argument all the time is that they never received the Dr. request
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours of H-E-B Pharmacy at 3540 Rayford Rd, Spring?
H-E-B Pharmacy is open Monday to Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy at Rayford Rd accept walk-in customers for COVID-19 and flu vaccinations?
Yes, COVID-19 and flu vaccines are available on both a walk-in and appointment basis at this location.
What payment methods are accepted at H-E-B Pharmacy on Rayford Rd?
They accept American Express, Android Pay, Apple Pay, cash, check, contactless payments, Discover, Mastercard, Samsung Pay, and Visa.
Does H-E-B Pharmacy offer prescription delivery services?
Yes, H-E-B Pharmacy provides delivery services for prescriptions.
Where can I find more information about COVID-19 vaccines provided by H-E-B Pharmacy?
You can visit https://vaccine.heb.com/ for the latest H-E-B Pharmacy news regarding the COVID-19 vaccine, vaccine phases, and frequently asked questions.
What is the contact phone number for H-E-B Pharmacy in Spring, TX?
The main phone number for H-E-B Pharmacy at this location is +1 281-353-2420.
Is H-E-B Pharmacy located near any popular dining options?
Yes, it is close to restaurants such as Trilogy Brew, Honeysuckle White, Hokulia Shave Ice, Bao's Cafe, and Smoothie King, making it convenient to grab a meal before or after your pharmacy visit.
Are there any financial services near H-E-B Pharmacy that customers can use?
Nearby financial services include Wells Fargo Bank, Western Union, The Exchange Network ATMs, and Coinme currency exchange, offering convenient options for banking and money transfer.
What nearby health and wellness services can I find near H-E-B Pharmacy?
Close to H-E-B Pharmacy, you'll find services like The Joint Chiropractic, Rayford Modern Dentistry, Stemlyft Aesthetics Center, Massage Heights, and 1960 Family Practice Rayford for comprehensive wellness options.
Does H-E-B Pharmacy offer in-store pickup and mobile payment options?
Yes, H-E-B Pharmacy supports in-store pickup and accepts mobile NFC payments such as Apple Pay, Android Pay, and Samsung Pay.
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