H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 641 East Hopkins Street in San Marcos, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
Today it took me almost 40 minutes to get my prescription from the drive thru. I am assuming it’s a new employee because I’ve never seen him. The employee was moving very slow and didn’t sound too happy to be there. Called to voice my opinion and I was told that customers can come inside . Isn’t a drive thru for convenience? I felt that even the employee that answered the line was nonchalant about the service. I’ve never had this problem with the drive thru at this location. This location is way faster, but not today! The employee at the drive thru needs to be trained to be more efficient. Horrible experience!
CH
C H
Dec 9, 2025
5.0
We came by on a weekday morning to pick something up in the drive thru after a doctors visit and they filled it really quickly. There was some kind of issue with my insurance but we figured it out. Thank you!
NR
Nancy Rowell
Sep 27, 2025
5.0
Very fast to fill RX.
They drive thru van take awhile but they are
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
Where is H-E-B Pharmacy located in San Marcos?
H-E-B Pharmacy is located at 641 East Hopkins Street, San Marcos, TX 78666, USA.
What are the operating hours for H-E-B Pharmacy in San Marcos?
The pharmacy is open Monday to Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy in San Marcos offer COVID-19 vaccines and do they accept walk-ins?
Yes, H-E-B Pharmacy provides COVID-19 vaccines and accepts both walk-ins and appointments for vaccination.
Can I get my prescriptions delivered from H-E-B Pharmacy?
Yes, H-E-B Pharmacy offers delivery services for prescriptions and medications.
What payment options are accepted at H-E-B Pharmacy?
The pharmacy accepts American Express, Apple Pay, Android Pay, Cash, Checks, Contactless Payments, Discover, Mastercard, Samsung Pay, and Visa.
Does H-E-B Pharmacy require appointments for services?
No, H-E-B Pharmacy does not require appointments for most services, including vaccines.
What nearby grocery options are available when visiting H-E-B Pharmacy?
Nearby grocery options include the H-E-B supermarket and HEB San Marcos grocery store, convenient for combined pharmacy and grocery shopping.
Are there any coffee shops near H-E-B Pharmacy where I can relax?
Yes, Mochas & Javas coffee shop is nearby, offering a nice place to unwind before or after your pharmacy visit.
Where can I access financial services near H-E-B Pharmacy?
Financial services including Coinme, LibertyX Bitcoin ATM, Coin Cloud Bitcoin ATM, and Western Union are located nearby for your convenience.
What entertainment options are near H-E-B Pharmacy in San Marcos?
Redbox kiosks nearby provide music and DVD rentals, and the Bobcat Ballpark and Texas State Baseball fields offer sports entertainment close to the pharmacy.