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Brand Certified

H-E-B Pharmacy

3.8
(66 reviews)

Business Details

20935 US Highway 281 North, San Antonio, TX
78258, United States
(210) 491-2450
https://www.heb.com/pharmacy

About

PharmaciesH-E-B Pharmacy
H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 20935 US Highway 281 North in San Antonio, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.

Details

  • DeliveryAvailable
  • Requires appointmentNot available
  • Credit cardAvailable
  • DebitAvailable

Location

H-E-B Pharmacy
20935 US Highway 281 North, San Antonio, TX
78258, United States

Hours

Monday8:00 AM - 8:00 PM
Tuesday8:00 AM - 8:00 PM
Wednesday8:00 AM - 8:00 PM
Thursday8:00 AM - 8:00 PM
Friday8:00 AM - 8:00 PM
Saturday9:00 AM - 6:00 PM
Sunday10:00 AM - 5:00 PM

Reviews

3.8
66 reviews
5 stars
39
4 stars
6
3 stars
3
2 stars
2
1 star
16
  • JF
    John F
    4 days ago
    5.0
    Good prices
  • AA
    Ari
    Feb 28, 2026
    5.0
    Best groceries store in the city. Always stocked up and staffs are always friendly
  • KC
    K C
    Jan 4, 2026
    1.0
    Horrendous and the customer service is non existent, always a nightmare due to long waits and the staff acts miserable. I wish the manager would see this and manage correctly bc it’s never the staffs fault it’s the manager who tolerates it.
  • CG
    Charlene Gieptner
    Nov 14, 2025
    5.0
    EXCELLENT!!!!!! So very nice and always willing to help and explain all about the medications if they are new to you. Thank you for always having such a nice staff.
  • JN
    Jamie Nickles
    Nov 18, 2022
    1.0
    WORST EXPERIENCE EVER!!!! Got there @11:30 and they said they would call in 2 hours because they had BOTH my prescriptions and had to make sure with my doctor even though he was the one to give me the prescriptions. THEY NEVER CALLED. So i went back 4 hours later and they still hadn't called my doctor and so they had me wait for them to call and they told me that they could give me the prescription only ONE though. They then told me that they didn't have the other prescription even though they told me they had both. Then told me to go to another H-E-B.

Frequently Asked Questions About H-E-B Pharmacy

Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?

Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions

Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?

COVID-19 and flu vaccines are available on both a walk-in or appointment basis

Brand Certified Facts from H-E-B Pharmacy

This information is certified by H-E-B Pharmacy and published from the brand's official system of record. Data is distributed through an enterprise-grade knowledge management platform. Learn more about our data sources
Certified April 12, 2026Yext Knowledge Graph
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