H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 6818 South Zarzamora in San Antonio, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
Good place to shop if you're not in a rush because parking is a nightmare most times
JW
Jack Williams
Mar 19, 2026
5.0
IT WAS QUICK.
I WENT IN AND CAN'T OUT QUICK.
IT WAS A LITTLE BUSY LIKE MOST HEB.
GOT IN LINE ON THE EXPRESS LANE. IT TOOK ME LIKE 2 MINUTES IN LINE.
I SCAN, PAID.
NO HASSLE AT ALL.
HAVE A BLESSED DAY ♥️
AV
Angela Valdez
Feb 3, 2026
1.0
It seems like every time I try to get prescriptions filled or have to pay out of pocket because insurance won’t go through there is always miscommunication with staff they genuinely could care less I’m calling to switch pharmacies today because I don’t think things will ever change
JE
Jennifer Envy
Jan 27, 2026
1.0
HEB the store itself is great, the pharmacy is TRASH. Been trash for years thats why i stopped using them but recently my awesome pharmacy (shoutout to SAMS on Zarzamora use that pharmacy instead) had a med shortage so I stupidly had it xferred over here thinking that HEB cant possibly mess it up but yes it took them forever to call Sams to initiate transfer i had to call them and bug them to do it then because of this med being $50 more expensive vs amazon I requested to instead have it sent to Amazon from HEB and its been such a hassle from both HEB and Amazon its been a very frustrating process and while im stuck waiting for my meds these two giant trash corporations are making this process difficult. I have to wait until my doc office opens tomorrow to just have them send it directly to a diff pharmacy. I wish Sams didnt have the med on backorder I never have issues with them!!!
JG
Jackie Gutierrez
Jan 20, 2026
1.0
Very disappointed with the pharmacy service at this H-E-B. I was simply trying to pick up medications for my sick kids after a very long day. I had just received a phone call saying the prescriptions were ready, yet the pharmacy staff rudely told me they weren’t. Had to mention that I had just received a phone call prior to getting into pick up line. No customer service, and an unnecessary attitude. When you’re dealing with sick children, the last thing you want is to be treated poorly. I expected much better.
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours for H-E-B Pharmacy at 6818 South Zarzamora?
H-E-B Pharmacy is open Monday to Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy accept walk-in customers for COVID-19 and flu vaccines?
Yes, H-E-B Pharmacy offers COVID-19 and flu vaccines on both a walk-in and appointment basis.
Where can I find the latest information about COVID-19 vaccines at H-E-B Pharmacy?
You can visit https://vaccine.heb.com/ for the latest news, vaccine phases, and answers to frequently asked questions about COVID-19 vaccines at H-E-B Pharmacy.
What payment options are available at H-E-B Pharmacy in San Antonio?
H-E-B Pharmacy accepts American Express, Mastercard, Visa, Discover, cash, check, Apple Pay, Android Pay, Samsung Pay, and contactless payments.
Does H-E-B Pharmacy offer delivery or pickup services?
Yes, H-E-B Pharmacy provides delivery services and also supports in-store pickup, although it does not currently offer curbside pickup.
What types of pharmacy and medical products can I find at H-E-B Pharmacy?
H-E-B Pharmacy offers medicines (both patent and proprietary), medical equipment and supplies, first aid supplies, contact lenses, optical goods, and services from optometrists and opticians.
Which nearby places can I visit after shopping at H-E-B Pharmacy on South Zarzamora?
Nearby you can find places like Flaming Bird By H-E-B, a chicken restaurant, T-Good's Shaved Ice for desserts, and Paraiso De Mexico, an ice cream shop and cafe, perfect for grabbing a bite after your pharmacy visit.
Are there financial services close to H-E-B Pharmacy?
Yes, near H-E-B Pharmacy you will find financial services like First National Bank, First Convenience Bank, Western Union for money transfers, and Coin Cloud Bitcoin ATM for currency exchange.
Is there a convenient grocery or supermarket option near H-E-B Pharmacy at South Zarzamora?
Yes, H-E-B plus and H-E-B Curbside Pickup & Grocery are nearby, offering convenient options for grocery shopping alongside your pharmacy visit.
How can I contact H-E-B Pharmacy for inquiries or prescriptions?
You can call H-E-B Pharmacy at +1 210-927-4596 or send a fax to +1 210-923-4869 for any inquiries or prescription orders.
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