H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 20935 US Highway 281 North in San Antonio, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
EXCELLENT!!!!!! So very nice and always willing to help and explain all about the medications if they are new to you.
Thank you for always having such a nice staff.
CM
Cynthia Muirhead
Sep 23, 2025
1.0
I have nothing but problems when Jessica the pharmacy tech takes care me at the drive -thru window. I go to the Heb pharmacy located off Evans Road. I always prepay for my medication from home an sign. I am given a code. When I presented the code to Jessica she always states its not working an we have to do it the "old fashion way". Then she tells me my order is not ready. Which I told her it is ready that I had received a text message stating so. She looks again 2 or 3 times and as usual she finds my medication. She also charge my card twice doing it the "old fashion way". I told her I prepaid. She has charge my cards multiple time in the past stating "your card did go through". "Looks like the machine is acting up again. Its rebooting". She has also given me someone elses medication twice in the past which is a total HIPPA violation. I not only have the patients medication I also have their address and date of birth. She is completely incompetent. I have NEVER had any problem with any other pharmacy tech but her. What should of been a pleasant experience and a quick trip turn out to be the worse experience ever. I dread it when I see her at the window because I know I will be there for 30 minutes trying to SORT things out!!!! Management really needs to look in to this. Some thing needs to be done. No one should ever have to experience this when picking up their medication.
GG
Gigi
Sep 22, 2025
1.0
Contemplating switching pharmacies all together. I just came to pick up a prescription, and I even got through all the steps and things to speed up the process through the app, but they always have some sort of issue with the transaction. Today I had old lady Jessica laughing at me as I'm frustratedly telling her how idk what code they need when I never get a code for the pickup I prepay for, and this was after I watch 3 cars in the second lane pass through because heaven know what BS problem they had with the car in front of me. Someone needs to take her off the customer service line because literally the reason I keep coming back to HEB is the customer service and the last thing anyone wants is this old lady laughing at them behind her glass window in the drive thru when she's already so slow that the people that are waiting are frustrated by the time they get to the window.
I've had this problem quite a few times since the stupid change they made on the app, but this was the first time I've had someone so petty and rude, that I had to turn and park so I could write about how trash this transaction was.
SS
Summer Sosa
Sep 20, 2025
5.0
This HEB Plus has an awesome dining area with a lot of tables/chairs, a counter with two microwaves and two ovens for preparing your food, along with plasticware, napkins, and condiments for your convenience! And, it's right by the restrooms! Why aren't all the Plus locations set up this way? It's very helpful for courier drivers who are always on the move, and are tired of eating fast food while working from their vehicles, so thank you, HEB!
JT
Jennifer Taylor
Sep 19, 2025
5.0
Bri was awesome. Quick and friendly service. My prescription had a ridiculously high out of pocket and she showed me how to get manufacturer coupon that cut my payment down by $500!!!
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours of H-E-B Pharmacy at 20935 US Highway 281 North?
H-E-B Pharmacy is open Monday to Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy offer COVID-19 and flu vaccines, and do they accept walk-ins?
Yes, H-E-B Pharmacy provides COVID-19 and flu vaccines and accepts both walk-in and appointment visits for these vaccinations.
Is delivery or in-store pickup available at H-E-B Pharmacy?
Yes, H-E-B Pharmacy offers both in-store pickup and delivery services for prescriptions and health products.
What payment options does H-E-B Pharmacy accept?
H-E-B Pharmacy accepts American Express, Android Pay, Apple Pay, cash, check, contactless payment, Discover, MasterCard, Samsung Pay, and Visa.
How can I find more information on H-E-B Pharmacy services online?
You can visit https://www.heb.com/pharmacy/common/landing to view all H-E-B Pharmacy services and information.
Is H-E-B Pharmacy wheelchair accessible and does it provide free Wi-Fi?
Yes, H-E-B Pharmacy has wheelchair accessible parking and offers free Wi-Fi to customers.
Where can I get cash or Bitcoin ATM services near H-E-B Pharmacy?
Nearby ATMs include Margo Bitcoin ATM, Coin Cloud DCM, Coinme, and an H-E-B ATM, providing cash and cryptocurrency services conveniently close to the pharmacy.
What dining options are available near H-E-B Pharmacy for a quick meal or smoothie?
You can visit Jamba for smoothies and sandwiches, Honeysuckle White for fast food, or Cactus Coffee Shop for breakfast and drinks, all located nearby the pharmacy.
Are there medical or urgent care facilities near H-E-B Pharmacy?
Yes, RediClinic Stone Ridge is a nearby urgent care clinic and medical center that you can visit before or after your pharmacy visit.
What makes H-E-B Pharmacy stand out according to customer satisfaction?
H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the third consecutive year in 2023, highlighting its dedication to quality service and care.