H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 8900 Hwy 6 in Missouri City, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
Pharmacy drive thru is so slow. Make people go inside if their medicine is not ready. There is no reason why anyone has to be stuck in your drive thru without anyway to exit for 30 minutes. You are blocked in.
Make drivers get out of the line and go in to do their transactions. Leave the drive thru for those that have prepaid. What is the point of prepaying on your app???
LT
Lisa Tagliarino
Dec 22, 2025
5.0
HEB Sienna Pharmacy has been our family pharmacy for close to 10 years now. The staff, specifically, Gabby and Marie, go out of their way to provide fantastic customer service. Even though they see hundreds of people a day, they make you feel like it’s a small town pharmacy, similar to the hometown pharmacy I grew up with. They always remember my name and are able to help with any issues that may arise. I drive past two other neighborhood pharmacies to go to HEB! They’ve made it worth the extra time. Thank you for going above and beyond for your customers, Gabby and Marie!
EE
Eddie Elizondo
Nov 29, 2025
5.0
The staff in the pharmacy is great. They all treat you with lots of respect and always makes you feel good to continue to come back.
DG
david garza
Nov 23, 2025
5.0
I took my youngest (11yo) son to the pharmacy to get a flu shot with me. Dylan helped us and was awesome. My son was very anxious and having a hard time. This was.pur second attempt at a flu shot. Dylan was very patient and accomidating. It took about 15 minutes longer than it should have, but we got it done and my son's stuffed animal also got a shot and candy. Thank you, Dylan!
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
Where is the H-E-B Pharmacy located in Missouri City?
The H-E-B Pharmacy is located at 8900 Hwy 6, Missouri City, TX 77459.
What are the operating hours of H-E-B Pharmacy?
The H-E-B Pharmacy is open Monday through Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy provide COVID-19 vaccines and do they accept walk-ins?
Yes, H-E-B Pharmacy provides COVID-19 vaccines and accepts both walk-ins and appointments for vaccinations.
What payment options are accepted at H-E-B Pharmacy?
H-E-B Pharmacy accepts American Express, Android Pay, Apple Pay, Cash, Check, Contactless Payment, Discover, Mastercard, Samsung Pay, and Visa.
Does H-E-B Pharmacy offer delivery services?
Yes, H-E-B Pharmacy offers delivery services for your convenience.
Where can I find more information about H-E-B Pharmacy services online?
You can view all H-E-B Pharmacy services by visiting https://www.heb.com/pharmacy/common/landing.
Which nearby places could be useful for customers visiting H-E-B Pharmacy?
Customers may find The Exchange Network ATM, First Community Credit Union - Sienna, and several nearby restaurants like Waffle Social Club and Jason's Deli useful when visiting H-E-B Pharmacy.
What medical facilities are located near H-E-B Pharmacy?
Nearby medical facilities include RediClinic Sienna Plantation, UT Physicians Multispecialty - Sienna, and Dr. Sadia Durrani's office.
Are there any beauty and spa services close to H-E-B Pharmacy?
Yes, beauty and spa options near H-E-B Pharmacy include TopAir, P & L Nail & Spa 2, Queen Nails Spa, PLnails2, and Amazing Lash Studio Sienna Plantation.
Can I find banking and ATM services near H-E-B Pharmacy?
Yes, nearby banking and ATM services include Wells Fargo Bank, HEB ATM, The Exchange Network, and Coinme currency exchange.