H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 19337 McDonald Street in Lytle, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
. The female pharmacist is a big bully she makes it difficult for you to fill your prescriptions. Customer service is terrible.
LL
LettyGDuhh!
Oct 30, 2025
5.0
I love Lytle pharmacy!
RB
R Benson
Sep 14, 2025
2.0
Good customer service and HEB used to be synonymous. However the customer service at HEB Lytle has become atrocious especially the pharmacy. Do better!
JB
John Barrera
Jul 8, 2025
3.0
I love H.E.B. and don't mind the wait times but sometimes the attitude form the staff is horrible.
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours of H-E-B Pharmacy in Lytle, TX?
H-E-B Pharmacy in Lytle is open Monday through Friday from 8:00 AM to 8:00 PM, Saturdays from 9:00 AM to 6:00 PM, and Sundays from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy in Lytle offer COVID-19 and flu vaccines?
Yes, H-E-B Pharmacy provides COVID-19 and flu vaccines, which are available on a walk-in or appointment basis.
How can I get the latest updates on COVID-19 vaccines from H-E-B Pharmacy?
You can visit https://vaccine.heb.com/ for the latest vaccine news, phases, and FAQs related to COVID-19 offered by H-E-B Pharmacy.
Does H-E-B Pharmacy offer delivery services for prescriptions?
Yes, H-E-B Pharmacy provides delivery services for prescriptions.
What payment methods are accepted at H-E-B Pharmacy in Lytle?
H-E-B Pharmacy accepts American Express, Mastercard, Visa, Discover, cash, check, Apple Pay, Android Pay, Samsung Pay, and contactless payments.
Where is H-E-B Pharmacy located in Lytle?
H-E-B Pharmacy is located at 19337 McDonald Street, Lytle, TX 78052, United States.
Are appointments required for vaccinations at H-E-B Pharmacy in Lytle?
No, appointments are not required for COVID-19 and flu vaccinations; walk-ins are welcome.
What nearby places can I visit before or after my pharmacy visit at H-E-B Pharmacy?
Nearby you can visit restaurants like Honeysuckle White, Taco Bell, and Whataburger for a meal, or enjoy services at Great Clips salon and Lytle Nail and Spa for beauty treatments.
Is there a grocery store near H-E-B Pharmacy in Lytle for convenient shopping?
Yes, the main H-E-B grocery store and H-E-B Fresh Bites convenience store are nearby, making it easy to combine your pharmacy visit with grocery shopping.
Are there any transportation or travel options near H-E-B Pharmacy in Lytle?
While there is no direct transit station mentioned, nearby places like Days Inn by Wyndham San Antonio Lytle hotel can accommodate travelers visiting the area, and services like Margo Bitcoin ATM and Redbox offer added convenience.