H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 5225 A Buffalo Speedway in Houston, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
Always accurate and on time. I appreciate the hard work
CG
Clash Gamer
Feb 19, 2026
3.0
Fantastic food!
NP
Nhi Pham
Feb 12, 2026
3.0
You must try this!
JP
Josh Ponce
Dec 26, 2025
1.0
Service is garbage and they have let two prescriptions expire two months in a row without any calls or notifications. Get your Rx filled somewhere else
LH
Lily Hendricks
Dec 5, 2025
5.0
I’ve came to get my vaccines a couple of times and all the workers here are so nice. I’ve looked up reviews for all H-E-B pharmacy and this one speaks for itself.
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
Where is H-E-B Pharmacy located?
H-E-B Pharmacy is located at 5225 A Buffalo Speedway, Houston, TX 77005, USA.
What are the operating hours of H-E-B Pharmacy?
The pharmacy is open Monday to Friday from 8 AM to 8 PM, Saturday from 9 AM to 6 PM, and Sunday from 10 AM to 5 PM.
Does H-E-B Pharmacy offer COVID-19 vaccinations?
Yes, H-E-B Pharmacy provides COVID-19 vaccinations and information can be found at https://vaccine.heb.com/.
Can I walk in for a COVID-19 or flu vaccine at H-E-B Pharmacy?
Yes, COVID-19 and flu vaccines are available on both a walk-in and appointment basis.
What payment methods are accepted at H-E-B Pharmacy?
The pharmacy accepts American Express, Android Pay, Apple Pay, Cash, Check, Contactless Payment, Discover, Mastercard, Samsung Pay, and Visa.
Does H-E-B Pharmacy provide delivery and in-store pickup options?
Yes, delivery and in-store pickup services are available at H-E-B Pharmacy.
What types of products and services does H-E-B Pharmacy offer?
H-E-B Pharmacy offers medicines, medical equipment and supplies, first aid supplies, contact lenses, optometrist and optician services, and optical goods.
Which nearby restaurants can I visit after my pharmacy visit?
Close by are Buca Di Beppo, Qin Dynasty (Chinese and Asian cuisine), P.ZA Kitchen (pizza), Shiva (Indian restaurant), Smashburger, Booster Juice, Island Smoothie Juice Bar, and Buca di Beppo Italian Restaurant.
Are there any nearby services for dental health near H-E-B Pharmacy?
Yes, nearby dental services include Luxadent, Luxadent - Dentist in Houston, Gulf Coast Endo, and Lovett Dental.
What other useful nearby services and places can customers access near H-E-B Pharmacy?
Nearby services include KeyMe Locksmiths for locksmith needs, HEB ATM for cash withdrawal, Western Union for money transfers, and Crystal Children and Teacher Supply for educational materials.
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