H-E-B Pharmacy was ranked #1 in customer satisfaction for supermarket pharmacies by J.D. Power for the 3rd year in a row in 2023. At your nearby H-E-B Pharmacy located at 2300 N. Shepherd Drive in Houston, the health and safety of Texans is our top priority. As a trusted source for all routine childhood and adult immunizations, H-E-B Pharmacy is also a provider for COVID 19 vaccine. H-E-B is proud to continue our long-term tradition of taking care of Texans.
I went last night to pick up medicine for a friend who had just gotten out of surgery. She had been prescribed medicine for the nausea and pain. They did not call it in from the hospital till after 7:00. I went as soon as knew to go get it and walked in just as they were closing at 8:00 on the nose - the door was still open and the lights on. They turned the lights off with me standing there. I explained that they had a completed order and my friend really needed this medicine for pain management. The pharmacist shrugged her shoulders and turned her back on me. I was in total disbelief at how rude she was. Then the police officer who was there screamed at me to leave even though I had in no way been rude or aggressive and I had walked through the door when they were open. This was a completed prescription that was paid for, so literally all that needed to be done was get it out of the bin and hand it to me. The rudeness was needless and unacceptable, but what was really troubling to me was the lack of fundamentally caring about a fellow human being. My hope is that one day when they or someone in their family have a similar need, they will have someone who cares more than they do. I would never recommend someone fill a prescription at this pharmacy. One would have to question their competency if they care this little. I get prescriptions filled a the Kroger south of them on Shepherd and they are absolutely terrific. They are always smiling and always helpful.
A
กนกวรรณ วงศ์ศรี
Feb 22, 2026
3.0
Good vibes!
GB
Gerry “Javi” Barillas
Feb 21, 2026
1.0
👎 👎 Terrible staff a male pharmacist answered my call and was EXTREMELY rude about my prescription refill. The call took place on Saturday February 21st around 9 in the morning. Absolutely unacceptable 👎
NN
Nina
Jan 17, 2026
1.0
Had a really bad experience !!
The tall guy at drop off was extremely rude with a horrible mood .
I mentioned that I got a new insurance and he refused to add on the system.
He was super rude and ignored me .
( since was a brand new insurance - of course was not in the system)
I was never treated like this !
As a HEB customer this is frustrating- they should hire people who wanna do their job and treat people on a respectful way !!
RV
Ruben Velasquez
Dec 31, 2025
5.0
If you need meds covered by your insurance go to HEB pharmacy
Where can I find the latest H-E-B Pharmacy news regarding the COVID-19 Vaccine?
Please visit https://vaccine.heb.com/ to learn more about the vaccine, including current vaccine phases and answers to Frequently Asked Questions
Do H-E-B Pharmacies accept walk-ins for COVID-19 and flu vaccines?
COVID-19 and flu vaccines are available on both a walk-in or appointment basis
What are the operating hours of the H-E-B Pharmacy at 2300 N. Shepherd Drive?
The pharmacy is open Monday to Friday from 8:00 AM to 8:00 PM, Saturday from 9:00 AM to 6:00 PM, and Sunday from 10:00 AM to 5:00 PM.
Does H-E-B Pharmacy accept walk-in customers for COVID-19 and flu vaccines?
Yes, H-E-B Pharmacy offers COVID-19 and flu vaccines on both a walk-in and appointment basis.
Where can I find the latest information about COVID-19 vaccines at H-E-B Pharmacy?
You can visit https://vaccine.heb.com/ for the latest vaccine information, including current phases and FAQs.
What payment options are accepted at H-E-B Pharmacy?
H-E-B Pharmacy accepts American Express, Android Pay, Apple Pay, cash, check, contactless payment, Discover, Mastercard, Samsung Pay, and Visa.
Does H-E-B Pharmacy offer delivery services?
Yes, delivery is available for pharmacy orders.
Is H-E-B Pharmacy wheelchair accessible and do they have accessible parking?
Yes, the pharmacy has wheelchair accessible parking and is accessible for customers with disabilities.
Which nearby places can I visit near H-E-B Pharmacy at 2300 N. Shepherd Drive?
Nearby places include H-E-B supermarket and grocery store, Mico’s Hot Chicken restaurant, Memorial Hermann GoHealth Urgent Care, and Blue Rhino Propane Exchange.
Are there fitness centers close to H-E-B Pharmacy for customers interested in health activities?
Yes, nearby fitness options include Studio Fitness, Facet Seven Heights gym, Digg Deep Fitness and Nutrition, and 9AM Girl Power by Rig Dog CrossFit.
What dining options are available near H-E-B Pharmacy?
Customers can enjoy nearby restaurants like Taqueria Don Tin (Mexican cuisine), Copper Penny (Chinese restaurant), and Pipers Burger (burger and barbecue).
Is there an ATM available near H-E-B Pharmacy for convenient cash withdrawals?
Yes, there are several ATMs nearby including HEB ATM, Coinme, Coin Cloud Bitcoin ATM, and The Exchange Network.
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