Need a pharmacy in Salem, OR? Visit Safeway Pharmacy at 5660 Commercial St SE for prescription refills, flu shots, COVID-19 vaccines, and walk-in vaccines close to home.
Safeway Pharmacy in Salem also offers everyday pharmacy services including medication reviews, pet prescriptions, blood pressure support, diabetes consultations, and health screenings, making it easier to take care of your health in one convenient stop.
Looking for vaccines in Salem? Safeway Pharmacy offers immunizations for children, teens, and adults, including flu, COVID-19, shingles, pneumonia, RSV, and back-to-school vaccines.
You can also manage prescriptions and schedule vaccines in the Safeway app. With most insurance plans accepted, Safeway Pharmacy is a convenient option for pharmacy care in Salem.
This is my all time favorite Pharmacy. Rachel, Sarah, Jamie, Abby and Neil are members of an awesome staff that is friendly, efficient and knowledgeable. And as they have added new staff they have been wonderful as well. I am impressed by how quickly I am able to get my prescriptions filled.
RP
randall p
Jan 25, 2026
1.0
one person working the counter. 15 minutes for them to take care of the 2 people in front of me. will take my prescriptions elsewhere. too bad, i liked the overpriced store
MO
Maegan O'Dell
Dec 26, 2025
1.0
Waited over 20 minutes.
AA
Ali A
Dec 5, 2025
1.0
been coming here for years and won’t be coming back, Tristian is awful and rude and shouldn’t be working in customer service with a horrible attitude.
TP
Thomas Ped
Oct 30, 2025
1.0
We are traveling through Salem, but needed to stop at a nearby urgent care for an emergency call. Prescriptions were were written to Safeway Commercial St pharmacy. Wow, what a grumpy bunch of rude people, including the phamacist. Do you do training for this behavior?
Does Safeway Pharmacy offer vaccinations, and which ones are available?
Yes! Safeway Pharmacy provides a wide range of vaccinations for children, teens, and adults. Popular vaccines available include pneumonia, flu (influenza), COVID-19, shingles (Shingrix), and Tdap. Whether you need a routine immunization, a back-to-school shot, or a travel vaccine, Safeway Pharmacy makes it easy with walk-in availability and online appointment scheduling. Visit Safeway Pharmacy for convenient and reliable vaccination services near you.
Who should get the shingles shot?
Safeway Pharmacy offers the Shingrix shingles vaccine for adults aged 50 and older, as well as for adults 19 and older with weakened immune systems. The CDC recommends two doses, spaced 2 to 6 months apart, to protect against shingles and its complications. You can get vaccinated at Safeway Pharmacy even if you've had shingles before, received the Zostavax vaccine, or are unsure if you had chickenpox.
Does Safeway Pharmacy require an appointment for a vaccination?
No, Safeway Pharmacy does not require an appointment for vaccinations. Walk-ins are welcome, making it easy and convenient to get vaccinated on your schedule.
Why is reviewing my Medicare plan every year important?
Reviewing your Medicare plan every year is important because Medicare Advantage (Part C) and Medicare Prescription Drug Plans (Part D) can change annually. These changes may affect your coverage, out-of-pocket costs, and provider network. By reviewing your plan during the Medicare Annual Enrollment Period, you can ensure it still meets your healthcare needs and budget—and switch plans if necessary.
What vaccination services does Safeway Pharmacy offer?
Safeway Pharmacy provides a variety of vaccinations including pneumonia, flu (influenza), COVID-19, shingles (Shingrix), and Tdap for children, teens, and adults with walk-in availability and online appointment scheduling.
Do I need an appointment to get vaccinated at Safeway Pharmacy?
No appointment is required; Safeway Pharmacy welcomes walk-ins for vaccinations making it convenient to get vaccinated anytime during operating hours.
Who is eligible for the shingles vaccine at Safeway Pharmacy?
The Shingrix shingles vaccine is offered for adults aged 50 and older and adults 19 and older with weakened immune systems, with two doses recommended 2 to 6 months apart.
What are the regular operating hours of Safeway Pharmacy?
Safeway Pharmacy is open Monday through Friday from 9:00 AM to 1:30 PM and 2:00 PM to 9:00 PM, Saturdays 9:00 AM to 1:30 PM and 2:00 PM to 6:00 PM, and Sundays 10:00 AM to 1:30 PM and 2:00 PM to 6:00 PM.
Where is Safeway Pharmacy located?
Safeway Pharmacy is located at 5660 Commercial St SE, Salem, OR 97306, United States.
Can I transfer my prescription to Safeway Pharmacy?
Yes, you can easily transfer prescriptions by visiting the Safeway Prescription Transfer page online and filling out the required fields.
What payment options are accepted at Safeway Pharmacy?
Safeway Pharmacy accepts American Express, Android Pay, Apple Pay, Cash, Check, Diners Club, Discover, Mastercard, Samsung Pay, Traveler's Check, and Visa.
Are there nearby dining options to visit before or after Safeway Pharmacy?
Yes, nearby dining options include ZENSHI Handcrafted Sushi for sushi lovers, Domino's Pizza for quick pizza delivery, Starbucks for coffee and snacks, and The Stonefront bar and grill for a casual meal or drink.
What nearby services complement a visit to Safeway Pharmacy?
Nearby services include Quest Diagnostics for laboratory testing, U.S. Bank and Coinme for financial needs, and Rebecca's Rejuvenating Massage for wellness and relaxation.
How can I use public transport or other nearby facilities to get to Safeway Pharmacy?
While specific transit stations are not listed, you can utilize nearby landmarks such as Western Union or Redbox kiosks which are close by to orient yourself. The location is accessible and has wheelchair-accessible parking.
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