Certified by Region Vein: Demetrios J. Karamichos, M.D. • Apr 12, 2026
Vascular SurgeryMedical Clinic
You will receive nothing less than exceptional vein care at Region Vein. Region Vein has been voted "Best of the Region" for 4 straight years by the readers of the Northwest Indiana Times. Our team provides comprehensive, office-based, and minimally invasive care of venous insufficiency. Dr. Demetrios J. Karamichos, MD, RVT, RPVI, DAVLM, is a Diplomate of the American Board of Venous and Lymphatic Medicine and has been treating venous insufficiency for over 17 years. He is committed to minimally invasive varicose vein disease treatment.
Location
Certified by Region Vein: Demetrios J. Karamichos, M.D. • Apr 12, 2026
Certified by Region Vein: Demetrios J. Karamichos, M.D. • Apr 12, 2026
Monday10:00 AM - 6:00 PM
Tuesday8:00 AM - 5:00 PM
Wednesday8:00 AM - 5:00 PM
Thursday8:00 AM - 5:00 PM
Friday9:00 AM - 1:00 PM
SaturdayClosed
SundayClosed
Reviews
5.0
85 reviews
5 stars
83
4 stars1
3 stars1
2 stars0
1 star0
JJ
Jennifer Jacobs
Mar 2, 2026
5.0
I had Varithena treatment in February on both legs for my chronic venous insufficiency at Region Vein with Dr. Karamichos & his staff are wonderful.
They were able to get my insurance approved & set up a series of 5 appointments for my ultra sounds & injections finished within a month.
I am very happy with my results. You don’t have to wear the uncomfortable compression stockings afterwards either. Just walking right after your injection appointment for 20 mins. A+ for outcome, efficiency, & friendly staff.
DF
Dalia Flores
Feb 25, 2026
5.0
Dr Karamichos is amazing! Been going to him for years and have always had an awesome experience with his services. I can wear shorts now YAY!!! The staff is caring, patient and kind.
BJ
Barb Jakovich
Dec 4, 2025
5.0
If you want your legs to feel and look better, your in the right place. Dr.K and his staff are outstanding, I highly recommend
HB
Hector Blanco
Nov 5, 2025
5.0
Very professional facility. Not only the doctor, but also the staff. They also are very friendly and informative. Most importantly, the treatment is effective. The doctor does an outstanding job at treating all problem veins. I experienced pain in my legs for years wondering If I have blood clots, but he assured me that it was just varicose veins that could be treated with a few simple injections. Sure enough he treated them. If you have great insurance, give this place a call and make an appointment. Thank you all for a great experience and a successful outcome.
SG
Sonia Gonzales-Nieves
Jul 13, 2023
5.0
You cannot go wrong coming here to get your legs taken care of. The staff is amazing and also the doctor is very kind and compassionate. He always makes you feel very comfortable when you’re having procedures done. The Dr. Is very honest. I’m happy that I have found this office.
Thanks to my friend Dalia who recommended me to come to this wonderful office.
Frequently Asked Questions About Region Vein: Demetrios J. Karamichos, M.D.
What are varicose veins and spider veins?
Varicose veins are veins that have become enlarged and twisted, appearing as blue or purple cords bulging under the skin. They can cause discomfort, pain, and swelling, especially in the legs, and are often found on the thighs, calves, or inside of the leg. Pregnant women may also develop varicose veins around the buttocks and vagina. Varicose veins are caused by weakened or damaged valves that allow blood to flow backward and pool in the veins, resulting in their enlargement.
On the other hand, spider veins are smaller than varicose veins, closer to the skin’s surface, and often appear as short, jagged lines in red or blue. They can resemble spider webs or tree branches and are usually found on the legs or face, covering small or large areas of skin. Spider veins may not cause pain or discomfort but can be a cosmetic concern for some people. They can be caused by various factors such as hormonal changes, sun exposure, injuries, or the backup of blood.
How common are abnormal leg veins?
Abnormal leg veins are a common health condition that affects a significant portion of the population. In the United States, approximately 50 to 55% of women and 40 to 45% of men suffer from some form of vein problem. Varicose veins, a type of abnormal leg vein, affect half of people who are over 50 years. It’s important to note that while abnormal leg veins are common, they can also cause discomfort and lead to more serious health problems, so seeking treatment is recommended.
What causes varicose veins and spider veins?
Varicose veins and spider veins can be caused by a variety of factors, including:
Weak or damaged valves in the veins can cause blood to leak back and pool in the veins (venous insufficiency).
Increasing age, as the valves in your veins may weaken and not work as well.
Medical history, including being born with weak vein valves or having family members with vein problems.
Hormonal changes, such as those that occur during puberty, pregnancy, and menopause, or from taking birth control pills or other medicines containing estrogen and progesterone.
Pregnancy, which can cause an increase in the amount of blood in the body and put pressure on the veins.
Obesity or being overweight, which can put extra pressure on the veins.
Lack of movement, such as sitting or standing for a long time, which can force veins to work harder to pump blood to the heart.
Sun exposure can cause spider veins on the cheeks or nose of a fair-skinned person.
Injuries or trauma to the affected area.
It’s important to note that while spider veins rarely cause serious health problems, varicose veins can lead to discomfort, pain, and more serious health issues if left untreated. If you are experiencing symptoms of varicose or spider veins, it’s best to consult with one of our vein care specialists at Region Vein to determine the best course of treatment for you.
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