Mariano's Pharmacy in HOFFMAN ESTATES, IL is staffed with professionals dedicated to helping you lead a healthier life. Protect yourself and your family with vaccinations, medicine and more. Our pharmacists do more than prepare prescription refills and dispense medical supplies; they also offer advice on health topics, perform clinical services, and administer vaccinations, including the Tdap vaccine, measles vaccine, shingles vaccine, flu shots and more.
Need to request a prescription transfer or refill a medication? Our convenient online tools make it easy to manage your prescriptions quickly, simply and on your own schedule.
Consistently excellent service. Every employee I’ve interacted with at this Mariano’s pharmacy has been polite, patient, and genuinely helpful. They take the time to answer questions and make the process smooth every visit. They will help to save money too.
Really appreciate this team.
DD
David Doty
Nov 16, 2025
5.0
Very clean and organized. Nice meats. Good prices!!
MK
Mahyar Khalili
Dec 13, 2021
1.0
Came in today to pickup my prescription over four hours after my doctor sent it over to them. It was still not ready, thats just ridiculous! they have really started going downhill since Kroger took over. Do better marianos
RB
Rich Berrill
Dec 5, 2021
2.0
If I had made this review a year ago it would be very different, but the last several months the service level has gone noticeably downhill. We've been a customer of Mariano's pharmacy for 10 years and this store's specifically for 4 years ago when we moved to South Elgin and wanted to take the extra drive because of the service.
We've experienced several problems over the last 2 months, prescriptions not filled with no notification, prescriptions taking days longer than normal no late notification. 'We used to be able to get the option for next day refills online, now if it's within the next 5 days we're lucky. Most recently we went the day it should have been ready and they hadn't even started filling them yet. Add that, whenever we go in now there are different people. We used to always see 1 of 2 pharmacists who were amazing, went out of their way to help us.
DG
Dimitri GG
Mar 7, 2019
5.0
Stephanie at the pharmacy was super nice and helpful. Thank you so much!
Frequently Asked Questions About Mariano's Pharmacy
What services does Mariano's Pharmacy in Hoffman Estates offer?
Mariano's Pharmacy provides prescription refills, vaccinations (such as Tdap, HPV, shingles, flu shots), clinical services, health advice, and medical supplies.
What are the operating hours for Mariano's Pharmacy?
The pharmacy is open Monday to Friday from 9:00 AM to 1:00 PM and 1:30 PM to 8:00 PM, Saturday 9:00 AM to 1:00 PM and 1:30 PM to 6:00 PM, and Sunday 10:00 AM to 1:00 PM and 1:30 PM to 5:00 PM.
Does Mariano's Pharmacy require appointments for COVID-19 vaccinations?
Yes, appointments are required for COVID-19 vaccinations at Mariano's Pharmacy.
Which COVID-19 vaccines are offered at Mariano's Pharmacy?
They offer Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines.
Can I manage prescription refills online for Mariano's Pharmacy?
Yes, Mariano's offers convenient online tools to request prescription transfers and refill medications.
Is Mariano's Pharmacy wheelchair accessible and what payment methods are accepted?
Yes, the pharmacy is wheelchair accessible with accessible parking, seating, and restrooms. They accept credit cards, debit cards, mobile NFC payments, and paychecks; cash is not required.
Are delivery and curbside pickup options available at Mariano's Pharmacy?
Mariano's Pharmacy offers same-day delivery and curbside pickup services for customer convenience.
How can nearby places like Starbucks or SUBWAY enhance my visit to Mariano's Pharmacy?
After your pharmacy visit, you can enjoy coffee or snacks at nearby Starbucks or a sandwich at SUBWAY, making it easy to combine errands with dining.
What fitness options are available near Mariano's Pharmacy for a healthy lifestyle?
Nearby fitness centers like Anytime Fitness and Cross Kicks Fitness Express provide opportunities to stay active and complement the health services offered at Mariano's Pharmacy.
Are there any nearby specialty stores for vitamins or pet supplies close to Mariano's Pharmacy?
Yes, GNC and GNC Live Well nearby offer vitamins and supplements, and Bentley's Pet Stuff provides pet supplies, complementing your health and wellness needs.