Mariano's Pharmacy in Des Plaines, IL is staffed with professionals dedicated to helping you lead a healthier life. Protect yourself and your family with vaccinations, medicine and more. Our pharmacists do more than prepare prescription refills and dispense medical supplies; they also offer advice on health topics, perform clinical services, and administer vaccinations, including the Tdap vaccine, measles vaccine, shingles vaccine, flu shots and more.
Need to request a prescription transfer or refill a medication? Our convenient online tools make it easy to manage your prescriptions quickly, simply and on your own schedule.
Pharmacy Staff are so friendly - Serrenna, Madeline, Anita, etc... Always on top of things. Thank you guys :-)
DE
Douglas Evans
Sep 17, 2025
5.0
Best customer service that I’ve ever had at a pharmacy
These pharmacists and assistants are the absolute top of their field
I’m thankful that they assist in my health care
HL
He Llo
Aug 30, 2025
5.0
This was a good decision to come here.
RR
Ryan F (RFF)
Nov 19, 2020
5.0
I go out of my way now to fill my prescriptions at this Mariano's because of their pharmacy staff!! Everyone I have dealt with is AMAZING!! Sandy (one of the pharmacists) went out of her way to help me out and want to make sure she gets recognized for her excellent customer service and being just a great person!! Thank you!!!