Mariano's Pharmacy in Crystal Lake, IL is staffed with professionals dedicated to helping you lead a healthier life. Protect yourself and your family with vaccinations, medicine and more. Our pharmacists do more than prepare prescription refills and dispense medical supplies; they also offer advice on health topics, perform clinical services, and administer vaccinations, including the Tdap vaccine, measles vaccine, shingles vaccine, flu shots and more.
Need to request a prescription transfer or refill a medication? Our convenient online tools make it easy to manage your prescriptions quickly, simply and on your own schedule.
Superior service and every member of the staff is friendly, helpful and caring.
RN
Renee Neff
Jan 10, 2026
2.0
Unprofessional, and rude!!
AN
Alfred Nowakowski
Oct 18, 2025
5.0
The pharmacist Tanya and her entire staff always answer the phone! Truly amazing in this day and age!!
They answer all questions professionally and in a timely fashion. And always have a smile!
CE
Christian Evans
Feb 24, 2023
5.0
Hands down the BEST pharmacy I have dealt with. I have dealt with a lot of pharmacies and it’s usually a game of back and forth and at times takes days to fill orders. They claim they will fill them and you call or show up and yet again they’re not ready. This crew is on top of it!! They are very respectful, very attentive and will go out of their way to help you anyway they can handling insurance claims and helping with pricing. Curtis is always helpful and I’m super impressed by Tanya (Pharmacist) remembering me by name in person and voice by phone. I won’t use any other pharmacy and I recommend you do the same!!
NB
Noel Bartz
Oct 18, 2021
5.0
I am always very happy with the service the pharmacy gives me, they take their time so if I have to wait a bit that is fine as they give each customer their attention
Frequently Asked Questions About Mariano's Pharmacy
What vaccinations are offered at Mariano's Pharmacy in Crystal Lake?
Mariano's Pharmacy offers several vaccinations, including Tdap, HPV, shingles, flu shots, and COVID-19 vaccines such as Pfizer, Moderna, and Johnson & Johnson.
Do I need an appointment for a COVID-19 vaccine at Mariano's Pharmacy?
Yes, a COVID-19 vaccine appointment is required. Upon arrival, proceed to the pharmacy window and inform the attendant about your appointment.
What are the pharmacy hours of operation at Mariano's Pharmacy in Crystal Lake?
The pharmacy is open Monday to Friday from 9:00 AM to 1:00 PM and 1:30 PM to 8:00 PM, Saturday from 9:00 AM to 1:00 PM and 1:30 PM to 6:00 PM, and Sunday from 10:00 AM to 1:00 PM and 1:30 PM to 5:00 PM.
Can I refill or transfer my prescription online for Mariano's Pharmacy?
Yes, Mariano's Pharmacy offers convenient online tools to request prescription transfers or refill medications quickly on your own schedule.
Is Mariano's Pharmacy wheelchair accessible?
Yes, Mariano's Pharmacy offers wheelchair accessible parking, seating, and restrooms for your convenience.
Does Mariano's Pharmacy provide delivery and curbside pickup services?
Yes, Mariano's Pharmacy provides same-day delivery as well as curbside and in-store pickup options.
Are there other places nearby where I can grab a coffee when visiting Mariano's Pharmacy?
Yes, there are two Starbucks coffee shops nearby where you can enjoy coffee or smoothies before or after your visit to Mariano's Pharmacy.
If I'm visiting Mariano's Pharmacy, what grocery options are available nearby?
Mariano's Pharmacy is located near Mariano's supermarket and grocery store, enabling easy access to groceries and pharmacy services in one trip.
Are there any nearby clinics or urgent care centers close to Mariano's Pharmacy?
Yes, the Advocate Clinic at Walgreens is nearby, providing hospital and urgent care services that may complement the health services at Mariano's Pharmacy.
Can I find other related health services near Mariano's Pharmacy?
Nearby health-related services include For Eyes at Walgreens for eye care and nurse practitioners Jennifer C. Finch, NP and Ashley E. Wallen NP, offering additional health services.
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