Mariano's Pharmacy in CHICAGO, IL is staffed with professionals dedicated to helping you lead a healthier life. Protect yourself and your family with vaccinations, medicine and more. Our pharmacists do more than prepare prescription refills and dispense medical supplies; they also offer advice on health topics, perform clinical services, and administer vaccinations, including the Tdap vaccine, measles vaccine, shingles vaccine, flu shots and more.
Need to request a prescription transfer or refill a medication? Our convenient online tools make it easy to manage your prescriptions quickly, simply and on your own schedule.
I feel very grateful to have this as my home base pharmacy. The pharmacists at this Marianos are incredibly kind, helpful, and knowledgeable. I never have any trouble here getting my prescriptions filled and if there is an issue (supply issue etc) the pharmacists don’t hesitate to help you find a solution. Thank you guys for all that you do! (And special shout out to Tom- he is wonderful!!)
SJ
Sherry Jones
Sep 11, 2025
4.0
Mariano's pharmacy is pretty Cool, The Short pharmacist act little weird The lady, not the young one The Older one, but everybody else is pretty Cool,
LK
Lucinda Kamps
Aug 7, 2025
5.0
I don’t know her name, but the young woman that has been there every time I pick up my prescription… So so kind and friendly!
NM
Natina mcconachie
Jan 29, 2021
5.0
Nasrin goes above and beyond. Excellent customer service .
Frequently Asked Questions About Mariano's Pharmacy
What services does Mariano's Pharmacy offer to help me lead a healthier life?
Mariano's Pharmacy offers prescription refills, vaccination services including Tdap, HPV, shingles, and flu shots, advice on health topics, and various clinical services.
Where is Mariano's Pharmacy located?
Mariano's Pharmacy is located at 1500 N. Clybourn Ave. #C104, Chicago, IL 60610, USA.
What are the operating hours of Mariano's Pharmacy?
Open Monday to Friday from 9:00 AM to 8:00 PM, Saturday 9:00 AM to 6:00 PM, and Sunday 10:00 AM to 5:00 PM.
Do I need an appointment to receive a COVID-19 vaccine at Mariano's Pharmacy?
Yes, COVID-19 vaccine appointments are required. Please proceed to the pharmacy window and inform the attendant you have a vaccine appointment.
Which COVID-19 vaccines are available at Mariano's Pharmacy?
They offer Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines.
Can I manage my prescriptions online with Mariano's Pharmacy?
Yes, you can request prescription transfers and refill medications using Mariano's convenient online tools anytime.
What payment methods are accepted at Mariano's Pharmacy?
They accept credit cards, debit cards, mobile NFC payments, and checks. Cash is not required.
Are the pharmacy facilities wheelchair accessible at Mariano's Pharmacy?
Yes, they provide wheelchair accessible parking, seating, and restrooms to accommodate all customers.
What popular dining options are near Mariano's Pharmacy?
Nearby you can enjoy dining at Nando's Peri-Peri for Portuguese and African chicken dishes, Max and Leo's Artisan Pizza for American and pizza fare, or Yard House for vegetarian and bar options.
Are there entertainment venues close to Mariano's Pharmacy?
Yes, nearby attractions include AMC NEWCITY 14 cinema, ArcLight Cinemas, and Kings Dining & Entertainment offering bowling, dining, and bar experiences.
How can nearby transportation or parking help when visiting Mariano's Pharmacy?
Visitors can use nearby parking options like SP+ Parking and SP Plus Parking, making it convenient to access Mariano's Pharmacy without hassle.