Mariano's Pharmacy in CHICAGO, IL is staffed with professionals dedicated to helping you lead a healthier life. Protect yourself and your family with vaccinations, medicine and more. Our pharmacists do more than prepare prescription refills and dispense medical supplies; they also offer advice on health topics, perform clinical services, and administer vaccinations, including the Tdap vaccine, measles vaccine, shingles vaccine, flu shots and more.
Need to request a prescription transfer or refill a medication? Our convenient online tools make it easy to manage your prescriptions quickly, simply and on your own schedule.
I’m not sure what’s slower: the service or the staff’s ability to use their own system. Every time I come here, it’s the same story—unhappy faces and zero help. It’s pathetic that they can’t find a returning patient’s profile. With the exception of one competent middle-aged gentleman, the staff here are completely unprofessional. It feels like a chore for them to even speak to you.
VM
vanna Mcmillan
Sep 16, 2025
1.0
Pharmacist should find a different job .. very miserable person’ ii called early morning to see if they had a specie medication and they did my dr told me to make sure they do before she wriote it, and I forgot to mention to add my ID for protection because I had stolen scripts in the past this around 10am..
Dr gives me a new script of dosage and I get a text saying he won’t refill it, I told him that’s a new medication and HE WITH attitude he says no it’s not it’s the same one I see right here.. he checked and realized it’s I was right .. it was a different medicine, he then tells me “call your doctor and have her send a message of the okay an I’ll fill it” when I said “okay no problem” I guess he was hoping I would say never mind hang up? (It’s literally my prescription and it’s brand new, new dosage and no past of anything suspicions) he sighs angrily says “great!!” Like I just made his life sooooooo hard.. ??..
I had to bother My dr to explain the situation and she was annoyed with him as well being that it’s not a the same refill it’s a brand new prescription. And he could fill it but he’s just giving a hard time .. I call back 40 mins later to tell him I spoke with dr and he should have the message now or anytime he literally reads it and says wow yeah great I can refill it but please never call again and don’t call me so much in the future” …. I said sir you messaged me that you wouldn’t refill my prescription and told ME to call my dr for the okay I’m doing what you asked and he had a literal tantrum because I guess he just did not want to fill MY prescription .. he says that “your rushing me!! And this is weird snd your making it - … I don’t need these calls” ?? I never once rushed him or anything I am simply doing what my dr and this man asked me to do and just get my new medication. I’m very sorry you felt that I asked you do your job sir …
Script was ready for 4 hours he wouldn’t even call or send the message if was ready and he wouldn’t even check me out because I inconvenienced him THAT badly .. that was my first and last time using this pharmacy a person like that should never be in this line of work
DG
David Gross
Aug 29, 2022
5.0
Amy the pharmacist at this location should be the template for corporate to have at every Mariano's pharmacy's. She went above and beyond to help me with getting the medication i need to maintain my health. All around happy with her.
JB
Jane Brinkley
Dec 4, 2019
5.0
The staff are genuinely helpful and go the extra mile to get my prescriptions filled and covered by insurance.
Frequently Asked Questions About Mariano's Pharmacy
What services does Mariano's Pharmacy in Chicago offer?
Mariano's Pharmacy offers prescription refills, vaccinations including Tdap, HPV, shingles, and flu shots, health advice, and clinical services.
What are the vaccination options available at Mariano's Pharmacy?
They provide several vaccinations including Tdap, HPV, shingles vaccine, flu shots, and COVID-19 vaccines by Pfizer, Moderna, and Johnson & Johnson.
Do I need an appointment for the COVID-19 vaccine at Mariano's Pharmacy?
Yes, a COVID-19 vaccine appointment is required before receiving the vaccine at Mariano's Pharmacy.
What are the operating hours of Mariano's Pharmacy?
Mariano's Pharmacy is open Monday to Friday from 9:00 AM to 1:00 PM and 1:30 PM to 8:00 PM, Saturdays 9:00 AM to 1:00 PM and 1:30 PM to 6:00 PM, and Sundays 10:00 AM to 1:00 PM and 1:30 PM to 5:00 PM.
Can I refill my prescriptions online at Mariano's Pharmacy?
Yes, you can request prescription transfers or refill medications using Mariano's convenient online tools.
What payment methods are accepted at Mariano's Pharmacy?
Mariano's Pharmacy accepts payment via cash, credit cards, debit cards, and mobile NFC payments.
Is Mariano's Pharmacy wheelchair accessible?
Yes, Mariano's Pharmacy provides wheelchair accessible parking, seating, and restrooms to accommodate all customers.
What nearby places can I visit before or after my visit to Mariano's Pharmacy?
You can visit Mariano's Fresh Market for groceries, Starbucks for coffee, or Chicago Cake Art for bakery treats nearby Mariano's Pharmacy.
Are there dining options near Mariano's Pharmacy?
Yes, nearby eateries include Chickpea (Middle Eastern cuisine), Lao Peng You (Chinese and Asian food), McDonald's for fast food, and WHISK for American dining.
What other services and shops are located near Mariano's Pharmacy?
Nearby, you can find the US Bank, Redbox rental kiosks, Western Union money transfer services, art galleries like Jason Guo INC and Gallery 2052, as well as several beauty salons such as Sine Qua Non Salon and Allure Beauty Lounge.
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