Welcome to a truly different kind of dental care. At MedPlex Dental Holistic Dentistry, our focus is on ethical, minimally invasive and holistic dentistry that places your long-term health first. Dr. Roberto Castellini, one of the top holistic dentists in the state, has led our trusted practice in Orlando since 1998. We are committed to providing medically necessary care in a warm, supportive environment. Our team speaks Spanish and Portuguese and is dedicated to your comfort and well-being.
Our office specializes in safe mercury filling removal using certified protocols, ozone therapy, and CBCT Imaging. His biomimetic philosophy focuses on preserving natural tooth structure and supporting healing with the body’s own resources. Our holistic dentist in Orlando, FL, maintains full control over your care – ensuring every treatment plan is guided by integrity and your long-term health.
Location
Certified by MedPlex Dental Holistic Dentistry • Mar 01, 2026
Certified by MedPlex Dental Holistic Dentistry • Mar 01, 2026
Reviews
4.8
306 reviews
5 stars
291
4 stars1
3 stars0
2 stars2
1 star
12
What are people saying?
AI-generated from recent customer reviews
Patient Care
Dr. Castellini is praised for his compassionate and attentive approach, making patients feel valued and heard.
Holistic Approach
Many reviews highlight the office's commitment to holistic dentistry, with a focus on safe and biocompatible treatments.
Professionalism
The staff is consistently described as professional, knowledgeable, and friendly, contributing to a positive overall experience.
Scheduling Issues
Some customers reported frustrations with scheduling and appointment changes, indicating a need for improvement in this area.
Insurance Transparency
A few reviews expressed concerns about billing practices and insurance transparency, suggesting potential issues with upfront payment expectations.
KG
Kayla Grison
1 day ago
5.0
Castellini and his team are absolutely fantastic. They're super gentle and make you feel at ease, even when you're getting a procedure that might normally make you squirm. They're also really straightforward and honest with you, explaining everything they're doing and why. It's great to have a dentist who doesn't sugarcoat things, but still manages to make the whole experience really comfortable and stress-free. Highly recommend!
MM
Margot Mitchell
2 days ago
5.0
Dr. Castellini at MedPlex Dental is truly exceptional. He takes a minimally invasive, “only what’s necessary” approach to repairing teeth, and really listens to his patients' needs. My son and I were both fitted for night guards, and we’re so much better off compared to our experiences with other dentists in the past.
Any time I have sensitivity or feel anxious, he is especially patient and careful, always making sure I’m comfortable. He was also wonderful with my son, kind and reassuring throughout. After such a positive experience, I’m now bringing my husband as well. We’re so grateful to have found such thoughtful, conservative care! I happily drive 40 minutes for Dr. Castellini.
DA
Dawn Acocella
Feb 12, 2026
5.0
I have had such a great experience at Medplex. They were actually my second opinion. I was told at the first dentist that I would need 6 crowns. However, Dr Castellini with his knowledge of dentistry was able to save all of those teeth. I have saved so much money. Even paying upfront was not an issue because they billed my insurance company and a good portion of my bill was covered. He was so gentle that before I left after each treatment I scheduled my next visit. Also finding an office that has considerate staff and a fantastic Dentist is unheard of these days. I would recommend Dr Castellini to anyone that is looking for a great dentist and office staff.
CC
Confetti and Creativity
Feb 12, 2026
5.0
I had an incredible experience with Dr. Castellini and his team. After years of living with severe jaw pain and feeling like I wasn’t getting real answers, I finally felt heard and supported. Dr. Castellini took the time to truly listen to my concerns and helped guide me to discover that I have multiple dental cavitations.
What stood out most was his genuine care and patience. He never made me feel rushed, always took the time to answer my questions, and was even willing to take phone calls when I needed extra support. As someone also dealing with Lyme disease, I deeply appreciated that he looked at my health holistically and offered thoughtful recommendations beyond just dentistry.
If you’re looking for a compassionate, knowledgeable holistic dentist who truly cares about your overall well-being, I cannot recommend Dr. Castellini enough.
HV
Hersha V
Feb 4, 2026
5.0
I have been going to Medplex Dental for over 8 years, and Dr. Castellini continues to amaze me every time with his professionalism and exceptional skill in dentistry. In addition, the staff are the embodiment of compassion and support. Five stars is simply not enough. You will not regret receiving services at Medplex Dental, you will definitely feel valued and heard as an individual.
Frequently Asked Questions About MedPlex Dental Holistic Dentistry
What is the address of MedPlex Dental Holistic Dentistry?
MedPlex Dental Holistic Dentistry is located at 7350 Sandlake Commons Blvd, Suite #1121, Orlando, FL 32819.
What are the operating hours of MedPlex Dental Holistic Dentistry?
The office is open Monday through Thursday from 8:30 AM to 4:30 PM, and Friday from 8:30 AM to 2:00 PM. It is closed on Saturdays and Sundays.
What special dental practices does MedPlex Dental Holistic Dentistry offer?
They specialize in ethical, minimally invasive, and holistic dentistry including safe mercury filling removal using certified protocols, ozone therapy, and CBCT Imaging, focusing on preserving natural tooth structure.
Who leads MedPlex Dental Holistic Dentistry and what is their expertise?
Dr. Roberto Castellini, one of Florida's top holistic dentists, has led the practice since 1998, focusing on holistic and biomimetic dental care.
What languages are spoken at MedPlex Dental Holistic Dentistry?
The dental team speaks Spanish and Portuguese, ensuring a comfortable experience for diverse patients.
What payment options does MedPlex Dental Holistic Dentistry accept?
They accept multiple payment methods including American Express, Android Pay, Apple Pay, Cash, Check, Discover, Financing, Mastercard, PayPal, Samsung Pay, and Visa.
How can I make an appointment at MedPlex Dental Holistic Dentistry?
Appointments can be made through their contact page at https://www.orlandosmilemakeover.com/contact-us/.
What nearby medical specialists and facilities are close to MedPlex Dental Holistic Dentistry?
Nearby are Orlando Health hospital, Dr. P. Phillips Hospital Outpatient Rehabilitation, and multiple specialists including OB&GYN, podiatrists, gastroenterologists, orthopedists, and neurologists, offering comprehensive health services in the area.
What are some nearby wellness and rehabilitation centers for patients visiting MedPlex Dental?
Patients can find nearby wellness options like Florida Spine Sports and Rehabilitation, Spine Group Orlando, and TMS Treatment Center of America for physical therapy and mental health support.
Are there any aesthetic and skin care services near MedPlex Dental Holistic Dentistry?
Yes, the New U Med Spa Orlando offers O Shot Injections and there is also Orlando Laser Hair Removal Spa nearby for skin and hair removal treatments.
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