2-Topping Medium Pizza
$6.99
A custom pizza made to order. Choose from any of our delicious crust styles, excluding Handmade Pan or Paremsan Crust.
Brand Certified
Domino's Pizza
3.2(815 reviews)
Certified by Domino's Pizza • Jul 05, 2026
Business Details
250 W Houston St., San Antonio, TX
78205, United States
Certified by Domino's Pizza • Jul 05, 2026
(210) 527-9505
Certified by Domino's Pizza • Jul 05, 2026
https://www.dominos.com/en/?utm_source=google&utm_medium=loclist&utm_campaign=localmaps
Certified by Domino's Pizza • Jul 05, 2026
About
Certified by Domino's Pizza • Jul 05, 2026
Pizza RestaurantRestaurant Delivery ServiceTake Out RestaurantFast Food RestaurantDomino's Pizza
Looking for great pizza in San Antonio? At Domino’s, we’re passionate about bringing you the best pizza experience, whether you're carrying out or ordering pizza delivery. Whether you’re craving thin, foldable New York Style pizza or a thick, Handmade Pan pizza, Domino’s has you covered. Or try our delicious, cheesy Parmesan Stuffed Crust pizza today! We offer more than just mouthwatering pizza—dishes like our fan-favorite mac and cheese, salads, pasta, and chicken wings will satisfy all your needs. We’ll give you great value with our unbeatable deals, making it easy to enjoy more for less. Wherever you are, the Domino's Pizza near you is here to satisfy your cravings with taste and quality. Order from 250 W Houston St. .
Details
- Dine-inNot available
- DeliveryAvailable
- TakeoutAvailable
- Credit cardAvailable
Location
Certified by Domino's Pizza • Jul 05, 2026
Hours
Certified by Domino's Pizza • Jul 05, 2026
Monday9:30 AM - 12:00 AM
Tuesday9:30 AM - 12:00 AM
Wednesday9:30 AM - 12:00 AM
Thursday9:30 AM - 12:00 AM
Friday9:30 AM - 1:00 AM
Saturday9:30 AM - 1:00 AM
Sunday9:30 AM - 12:00 AM
Menu
1 menu · 82 items
Explore offerings from Domino's Pizza on 250 W Houston St. in San Antonio, with popular mix and match, pizza, breads, and chicken available at this location.
Test Menu data- all locations
82 items
Mix and Match
Parmesan Bread Bites
$6.99
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan.
Stuffed Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Pepperoni Stuffed Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese and pepperoni - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Spinach & Feta Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese, fresh spinach and Feta cheese - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Bacon & Jalapeño Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese, smoked bacon and jalapeno peppers - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an addional charge.
Boneless Chicken
$6.99
Breaded chicken made with 100% whole white breast meat. Choose one or more dipping cups for an additional charge.
Hot Buffalo Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with hot buffalo sauce, ranch, a blend of cheese made with mozzarella and cheddar, and feta.
Sweet BBQ Bacon Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with sweet and smoky honey BBQ sauce, a blend of cheese made with mozzarella and cheddar, and crispy bacon.
Crispy Bacon & Tomato Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with garlic Parmesan sauce, a blend of cheese made with mozzarella and cheddar, crispy bacon and tomato.
Spicy Jalapeno-Pineapple Loaded Chicken
$6.99
Tender bites of lightly breaded, 100% whole breast white meat chicken, topped with sweet and spicy mango-habanero sauce, a blend of cheese made with mozzarella and cheddar, jalapeno and pineapple.
5-Cheese Mac & Cheese
$6.99
Our take on the classic. Penne pasta and a blend of cheddar, American, Parmesan-Asiago, mozzarella blend and Alfredo sauce, oven baked to creamy, bubbly perfection.
Spicy Buffalo 5-Cheese Mac & Cheese
$6.99
Our creamy, oven baked 5-cheese Mac & Cheese drizzled with buffalo sauce for a spicy kick.
Chicken Alfredo
$6.99
Grilled chicken breast and creamy Alfredo sauce mixed with penne pasta and baked to perfection.
Philly Cheese Steak
$6.99
Tender slices of steak, American and provolone cheeses, fresh onions, fresh green peppers and fresh mushrooms.
Chicken Bacon Ranch
$6.99
Grilled chicken breast topped with smoked bacon, creamy ranch and provolone cheese.
Italian
$6.99
Pepperoni and ham topped with banana peppers, fresh green peppers, fresh onions and provolone cheese.
Chicken Parm
$6.99
Grilled chicken breast, tomato-basil marinara, Parmesan- Asiago and provolone cheeses.
Buffalo Chicken
$6.99
Grilled chicken breast, ranch, fresh onions, hot buffalo sauce, provolone, cheddar and cheese made with 100% real mozzarella.
Classic Garden
$6.99
A crisp and colorful combination of grape tomatoes, red onions, carrots, red cabbage, cheddar cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Chicken Caesar
$6.99
The makings of a classic: roasted white meat chicken, Parmesan cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Cinnamon Bread Bites
$6.99
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Domino's Marbled Cookie Brownie
$6.99
An irresistibly warn and gooey blend of milk chocolate chunk cookie and fudge brownie. This sharable dessert is oven baked at the time of order and cut into 9 pieces.
Chocolate Lava Crunch Cakes
$6.99
Oven-baked chocolate cakes, crunchy on the outside with molten chocolate fudge on the inside.
Pizza
Spicy Chicken Bacon Ranch
Grilled chicken breast, creamy ranch, smoked bacon, jalapeños, provolone, and cheese made with 100% real mozzarella and finished off with a drizzle of buffalo sauce.
ExtravaganZZa ™
Pepperoni, ham, Italian sausage, beef, fresh onions, fresh green peppers, fresh mushrooms and black olives, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
MeatZZa™
Pepperoni, ham, Italian sausage and beef, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
Philly Cheese Steak
Tender slices of steak, fresh onions, fresh green peppers, fresh mushrooms, provolone and American cheese.
Honolulu Hawaiian
Sliced Ham, smoked bacon, pineapple, fresh green peppers, provolone and cheese made with 100% real mozzarella.
Pacific Veggie
Fresh spinach, fresh onions, fresh mushrooms, fresh onions, provolone and cheese made with 100% real mozzarella.
The People’s Pizza – Deluxe
Savory pepperoni and Italian sausage, fresh green peppers, fresh mushrooms, fresh onions, provolone and cheese made with 100% real mozzarella. We’ve combined our customers’ most ordered toppings into the perfect deluxe pizza.
Ultimate Pepperoni
Two layers of pepperoni sandwiched between provolone, Parmesan-Asiago and cheese made with 100% real mozzarella, then sprinkled with oregano.
Memphis BBQ Chicken
Grilled chicken breast, fresh onions, provolone, American cheese, cheddar, cheese made with 100% real mozzarella.
Wisconsin 6-Cheese
Feta, provolone, cheddar, Parmesan-Asiago, cheese made with 100% real mozzarella, then sprinkled with oregano.
Spinach & Feta
Creamy Alfredo sauce, fresh spinach, fresh onions, feta, Parmesan-Asiago, provolone and cheese made with 100% real mozzarella.
Build Your Own
A custom pizza made to order. Choose from any of our delicious crust styles, including Handmade Pan or Parmesan Stuffed Crust.
Breads
Parmesan Bread Bites
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan.
Cinnamon Bread Bites
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Stuffed Cheesy Bread
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Pepperoni Stuffed Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese and pepperoni - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Spinach & Feta Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese, fresh spinach and Feta cheese - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Bacon & Jalapeño Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese, smoked bacon and jalapeno peppers - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Chicken
Boneless Chicken
Breaded chicken made with 100% whole white breast meat. Choose one or more dipping cups for an additional charge.
Bone-in Wings
Marinated and oven-baked. Customize with your choice of dipping cup.
Hot Buffalo Bone-in Wings
Marinated and oven-baked, then smothered in hot buffalo sauce. Customize with your choice of dipping cup.
Honey BBQ Bone-in Wings
Marinated and oven-baked, then smothered in honey BBQ sauce. Customize with your choice of dipping cup.
Garlic Parmesan Bone-in Wings
Marinated and oven-baked, then smothered in garlic Parmesan sauce. Customize with your choice of dipping cup.
Sweet Mango Habanero Bone-in Wings
Marinated and oven-baked, then smothered in sweet mango habanero sauce. Customize with your choice of dipping cup.
Hot Buffalo Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with hot buffalo sauce, ranch, a blend of cheese made with mozzarella and cheddar, and feta.
Sweet BBQ Bacon Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with sweet and smoky honey BBQ sauce, a blend of cheese made with mozzarella and cheddar, and crispy bacon.
Crispy Bacon & Tomato Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with garlic Parmesan sauce, a blend of cheese made with mozzarella and cheddar, crispy bacon and tomato.
Spicy Jalapeno-Pineapple Loaded Chicken
Tender bites of lightly breaded, 100% whole breast white meat chicken, topped with sweet and spicy mango-habanero sauce, a blend of cheese made with mozzarella and cheddar, jalapeno and pineapple.
Pastas
5-Cheese Mac & Cheese
Our take on the classic. Penne pasta and a blend of cheddar, American, Parmesan-Asiago, mozzarella blend and Alfredo sauce, oven baked to creamy, bubbly perfection.
Spicy Buffalo 5-Cheese Mac & Cheese
Our creamy, oven baked 5-cheese Mac & Cheese drizzled with buffalo sauce for a spicy kick.
Chicken Alfredo
Grilled chicken breast and creamy Alfredo sauce mixed with penne pasta and baked to perfection.
Oven-Baked Sandwiches
Philly Cheese Steak
Tender slices of steak, American and provolone cheeses, fresh onions, fresh green peppers and fresh mushrooms.
Chicken Bacon Ranch
Grilled chicken breast topped with smoked bacon, creamy ranch and provolone cheese.
Italian
Pepperoni and ham topped with banana peppers, fresh green peppers, fresh onions and provolone cheese.
Chicken Parm
Grilled chicken breast, tomato-basil marinara, Parmesan- Asiago and provolone cheeses.
Buffalo Chicken
Grilled chicken breast, ranch, fresh onions, hot buffalo sauce, provolone, cheddar and cheese made with 100% real mozzarella.
Salads
Classic Garden
A crisp and colorful combination of grape tomatoes, red onions, carrots, red cabbage, cheddar cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Chicken Caesar
The makings of a classic: roasted white meat chicken, Parmesan cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Ranch
A flavorful creamy dressing with touches of buttermilk and garlic.
Balsamic
A light dressing with a blend of balsamic vinegar, oil and garlic.
Caesar
A savory dressing with a combination of garlic, anchovy and subtle notes of cheese.
Desserts
Chocolate Lava Crunch Cakes
Oven-baked chocolate cakes, crunchy on the outside with molten chocolate fudge on the inside.
Domino's Marbled Cookie Brownie
An irresistibly warn and gooey blend of milk chocolate chunk cookie and fudge brownie. This sharable dessert is oven baked at the time of order and cut into 9 pieces.
Cinnamon Bread Bites
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Drinks
Coca Cola®
Available in 20 oz and 2-liter bottles
Diet Coke®
Available in 20 oz and 2-liter bottles
Sprite®
Available in 20 oz and 2-liter bottles
Fanta® Orange
Available in 20 oz and 2-liter bottles
Dasani® Water
Available in 20 oz bottles
Dip Cups
Slice Sauce Dipping Cup
Creamy and zesty with a hint of Parmesan.
Ranch
A creamy buttermilk ranch dressing with hints of garlic and onion.
Blue Cheese
A creamy dressing with bits of aged blue cheese.
Hot Buffalo
Domino's own spicy buffalo sauce.
Honey BBQ
A sweet and smoky BBQ sauce with bold flavor.
Marinara
A sweet tomato sauce blended with garlic, basil and oregano.
Garlic
A buttery garlic sauce.
Sweet Mango Habanero
A perfect blend of sweet and spicy in one sauce.
Sweet Icing
A thick sweet icing with a hint of vanilla.
Reviews
3.2
815 reviews
5 stars
348
4 stars
85
3 stars
50
2 stars
30
1 star
302
- DMDiego MartinezJul 2, 20261.0HORRIBLE DO NOT PURCHASE!. Ordered pan pizza and the pan came out like crap! Undercooked extremely thin dough, and the employees allowed it to come out in such a horrible condition.
- AHAmanda HigginsJul 1, 20263.0My food was marked as delivered but didn't arrive for at least 30 minutes after it was marked as delivered. I was mad !! I could not reach the store number and genuinely thought I was out of luck with my food. only reason i bumped up my star rating to 3 is because Larry was a nice delivery driver.
- STsylvia torresJul 1, 20261.0My son and I were staying at the Doubletree Hotel, here in San Antonio TX. We placed an order with Dominos. We waited and waited, after 3 hours we finally gave up. The pizza was never delivered. We called the store several times only to get a busy signal. I was very disappointed. If there was a problem with our order, a simple phone call back would have been nice. We should have ordered from Pizza Hut, as we always have but my son watched the CEO/Owner of Dominos on EWTN and insisted we give our business to Dominos! What a mistake!
- WFWater tower and plane FanJun 12, 20265.0I have no idea what y’all talking about with some “Cold food”?! My order was Perfect. I come from Louisiana and am visiting here for a bit. Dominos made me feel at home. Wonderful food, and arrived super quick
- LRLUIS ENRIQUE RiveroJun 6, 20261.0New Domino's Pizza at Buena Vista and Zarzamora has poor customer service. I noticed they had recently opened and decided to give them a try. When I entered the store, nobody was at the register. Two employees were in the back having a conversation. They saw me but continued talking and never acknowledged me. After waiting about three minutes without being greeted or offered assistance, I decided to leave. First impressions matter, and unfortunately this experience left a negative impression. I took my business to one of the competitors nearby.
Frequently Asked Questions About Domino's Pizza
What are the operating hours for Domino's Pizza at 250 W Houston St., San Antonio?
Domino's Pizza is open from 9:30 AM to midnight from Monday to Thursday and Sunday, and until 1:00 AM on Friday and Saturday.
What types of pizza crusts does Domino's Pizza offer?
Domino's offers New York Style, Handmade Pan, and Parmesan Stuffed Crust pizzas.
What services does Domino's Pizza provide for ordering?
Domino's Pizza offers curbside pickup, delivery, and no-contact delivery services.
How can I order Domino's Pizza online?
You can order online for delivery or carryout through their official website or the following URLs: https://www.dominos.com/en/restaurants for delivery and https://www.dominos.com/en/restaurants?type=Carryout for carryout.
What payment options are accepted at Domino's Pizza?
Domino's accepts various payment methods including credit cards (Visa, Mastercard, American Express, Discover, Diners Club), cash, Bitcoin, PayPal, Apple Pay, Google Pay, Samsung Pay, Afterpay, Klarna, Zelle, checks, invoice, financing, and travelers checks.
Does Domino's Pizza offer vegetarian dishes?
Yes, Domino's Pizza serves vegetarian dishes to cater to diverse dietary preferences.
Which nearby entertainment venues can I visit before or after dining at Domino's Pizza?
You can visit the Alameda Theater and the Venues at San Fernando Cathedral, both located near Domino's, for theatre performances and cinema experiences.
Are there any nearby hotels close to Domino's Pizza for convenient dining?
Yes, the Holiday Inn Express San Antonio North Riverwalk Area is nearby, making it convenient for hotel guests to order or pick up Domino's Pizza.
Can nearby transit or community centers help customers find Domino's Pizza?
Yes, the San Fernando AT&T Community Center, which includes event planning and gym facilities, is nearby and can help orient customers to Domino's location at 250 W Houston St.
Is there a convenient mobile app for ordering Domino's Pizza in San Antonio?
Yes, you can use the Domino's Pizza app available on Android at https://play.google.com/store/apps/details?id=com.dominospizza and on iOS at https://apps.apple.com/us/app/dominos-pizza-usa/id436491861 to easily order your pizza for pickup or delivery.
Brand Certified Facts from Domino's Pizza
This information is certified by Domino's Pizza and published from the brand's official system of record. Data is distributed through an enterprise-grade knowledge management platform. Learn more about our data sources
Certified July 05, 2026Yext Knowledge Graph
- Address
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- Geo coordinates
- Legal business name
- Hours of operation
- Phone number
- Official website