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Panera Bread Sioux Falls welcomes guests to our café with warm hospitality and quality ingredients. We serve a variety of menu favorites for breakfast, lunch, and dinner—including fresh coffee, bakery items, salads, soups, and sandwiches—crafted to help you feel good about what you’re enjoying. Whether you’re dining in while enjoying complimentary Wi‑Fi, ordering online for Rapid Pick‑Up, enjoying delivery, or planning catering for a large group, Panera Bread Sioux Falls is here to make your day a little better. Food as it should be.
Explore offerings from Panera Bread on 5117 S Louise Ave in Sioux Falls, with popular sandwiches, soups & mac, salads, and pastries & sweets available at this location.
Smoked, pulled chicken raised without antibiotics, smoked Gouda, fresh avocado and cilantro, zesty sweet Peppadew™ peppers and chipotle sauce on Black Pepper Focaccia.
Smoked, pulled chicken, fresh mozzarella, vine-ripened tomatoes, red onions, fresh basil, chipotle aioli, salt and pepper on our Black Pepper Focaccia.
Black Forest ham, soppressata, provolone, romaine, red onion, sliced pepperoncini peppers, garlic aioli, and Greek dressing on our toasted French Baguette.
Melty fresh mozzarella, vine-ripened tomatoes, chopped basil, crisp romaine & lettuce blend, sprinkled with salt and pepper, and balsamic vinaigrette and garlic aioli drizzle on our Ciabatta.
Oven-roasted turkey breast, applewood smoked bacon with aged white cheddar, crisp mixed greens, vine-ripened tomatoes, sprinkled with salt and pepper, and our Signature Bravo sauce drizzle on our Tomato Basil Miche.
Oven roasted turkey breast, aged white cheddar, crisp mixed greens, vine-ripened tomatoes, red onions, garlic aioli, salt and pepper on our Country Rustic Sourdough.
A rich chunky chili with beef, kidney beans, fire roasted tomatoes and green chili peppers, simmered in a broth flavored with a blend of chilis, and cilantro.
Tender pieces of white-meat chicken simmered in a rich, perfectly seasoned homestyle chicken bone broth with curly egg noodles, sliced carrots, celery and herbs.
Vine-ripened pear tomatoes pureed with fresh cream for a velvety smooth flavor accented by hints of red pepper and oregano and topped with black pepper and sea salt croutons.
Romaine and crisp mixed greens tossed in a sweet white balsamic vinaigrette, topped with grilled chicken, grape tomatoes, red onions, toasted pecan pieces, feta, and apple chips.
Romaine and crisp mixed greens tossed in Green Goddess dressing, topped with grilled chicken, grape tomatoes, and pickled red onions, fresh avocado, applewood smoked bacon and a hard-boiled egg.
Romaine tossed in ranch dressing, with grilled chicken and drizzled with chipotle aioli, topped with fresh avocado, grape tomatoes, roasted corn, fresh cilantro, and blue corn tortilla strips.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, grilled chicken, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine tossed in Greek dressing, topped with grilled chicken, grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine tossed in Greek dressing, topped with grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine and crisp mixed greens tossed in ranch dressing, topped with grape tomatoes, pickled red onions, applewood smoked bacon, feta, and a hard-boiled egg.
A salty, chocolaty, caramel confection big enough to share. A large cookie with semi-sweet chocolate, milk chocolate, caramel pieces, pretzels and then topped with flake salt.
Soft and smooth with hints of citrus, roasted nut and chocolate. A blend of Central and South American beans. Light bodied with a bright sweetness. Freshly ground in cafes.
Subtle nutty tones with wonderful coffee flavor. Serves 10. Brewed fresh, so please allow additional 15 min./tote to prepare your order. 120 fl oz per tote.
Rich, bold and full-bodied, balanced with a smoky accent and sweet chocolate notes. Harvested from Central and South America. Serves 10. 120 fl oz per tote.
Carefully roasted from Arabica beans and freshly brewed. Brewed fresh, so please allow additional 15 min./tote to prepare your order. Serves 10. 120 fl oz per tote.
Smoked, pulled chicken, scrambled egg, white cheddar, zesty sweet Peppadew peppers, fresh avocado and cilantro, salt and pepper, and chipotle aioli on Ciabatta.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
Explore offerings from Panera Bread on 5117 S Louise Ave in Sioux Falls, with popular we’re here to help when and where you need us. available at this location.
We deliver your Panera favorites right to your door with contactless delivery. Just tell us where to leave your meal in the “Delivery Instructions” box when placing your order.
Panera pizza is here! Unbox the new flatbread pizzas in three varieties: margherita, chipotle chicken & bacon, and cheese. Pick it up, have it delivered, or grab it through the drive through for lunch or dinner.
This was a to-go order . The sandwiches and soups were very good but I ordered two cinnamon crunch bagels and received a plain one and one with one raisin in it.
MS
Madison Smith
5 days ago
3.0
I have been a Panera rewards member for a few years and I love my local Panera bread; however, it seems that recently (maybe since COVID?) they have switched to much lower quality produce and bakery items. The workers are always fast and friendly, but given the prices combined with the quality, I unfortunately don’t eat here much anymore
MH
Michael Howell
6 days ago
5.0
Angelina and the team made me a excellent salad & green tea today! Great experience & clean restrooms!
LH
Laura Hotzler
6 days ago
3.0
Better to order before you arrive, very crowded at order kiosk and doesn't work for people with mobility issues
BG
Bruce Gitlin
Jun 5, 2026
3.0
Poor selection of bread late in the day. The baguette was very hard, not nearly fresh. Prices are way too high for the items.
Does Panera Bread at 5117 S Louise Ave accept reservations?
No, Panera Bread does not accept reservations at this location.
What are the operating hours for dine-in and delivery at Panera Bread Sioux Falls?
Panera Bread is open from 6:00 AM to 9:00 PM Monday through Friday, and from 7:00 AM to 9:00 PM on Saturdays and Sundays for both dine-in and delivery services.
Is there a drive-thru available at this Panera Bread location?
Yes, this Panera Bread location has a drive-thru available for customer convenience.
What types of meals can I get at Panera Bread Sioux Falls?
You can enjoy breakfast, brunch, lunch, and dinner at Panera Bread Sioux Falls.
Can I order online and pick up quickly at Panera Bread Sioux Falls?
Yes, you can order online using Rapid Pick-Up and grab your food quickly at this location.
What payment methods are accepted at this Panera Bread?
Panera Bread accepts American Express, Cash, Discover, Mastercard, and Visa.
Does Panera Bread Sioux Falls offer catering and fundraising services?
Yes, they offer catering as well as fundraising services.
What are some nearby places of interest around Panera Bread Sioux Falls?
Nearby places include Sweet Amber Lynns candy store and restaurant, Botanical Rhapsody Organics (CBD store), Juice Stop smoothie and health food bar, and CherryBerry frozen yogurt and ice cream shop.
Are there any nearby fitness or wellness centers close to Panera Bread Sioux Falls?
Yes, nearby wellness and fitness options include Barre3 yoga studio and OsteoStrong Sioux Falls health center.
Which nearby locations can help customers with internet and media services near Panera Bread Sioux Falls?
Midcontinent Communications provides internet service, and Midco-Sioux Falls is a local television station near Panera Bread.
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