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Panera Bread Syracuse welcomes guests to our café with warm hospitality and quality ingredients. We serve a variety of menu favorites for breakfast, lunch, and dinner—including fresh coffee, bakery items, salads, soups, and sandwiches—crafted to help you feel good about what you’re enjoying. Whether you’re dining in while enjoying complimentary Wi‑Fi, ordering online for Rapid Pick‑Up, enjoying delivery, or planning catering for a large group, Panera Bread Syracuse is here to make your day a little better. Food as it should be.
Explore offerings from Panera Bread on 9542 Destiny USA Drive in Syracuse, with popular sandwiches, soups & mac, salads, and pastries & sweets available at this location.
Smoked, pulled chicken raised without antibiotics, smoked Gouda, fresh avocado and cilantro, zesty sweet Peppadew™ peppers and chipotle sauce on Black Pepper Focaccia.
Smoked, pulled chicken, fresh mozzarella, vine-ripened tomatoes, red onions, fresh basil, chipotle aioli, salt and pepper on our Black Pepper Focaccia.
Black Forest ham, soppressata, provolone, romaine, red onion, sliced pepperoncini peppers, garlic aioli, and Greek dressing on our toasted French Baguette.
Melty fresh mozzarella, vine-ripened tomatoes, chopped basil, crisp romaine & lettuce blend, sprinkled with salt and pepper, and balsamic vinaigrette and garlic aioli drizzle on our Ciabatta.
Oven-roasted turkey breast, applewood smoked bacon with aged white cheddar, crisp mixed greens, vine-ripened tomatoes, sprinkled with salt and pepper, and our Signature Bravo sauce drizzle on our Tomato Basil Miche.
Oven roasted turkey breast, aged white cheddar, crisp mixed greens, vine-ripened tomatoes, red onions, garlic aioli, salt and pepper on our Country Rustic Sourdough.
A rich chunky chili with beef, kidney beans, fire roasted tomatoes and green chili peppers, simmered in a broth flavored with a blend of chilis, and cilantro.
Tender pieces of white-meat chicken simmered in a rich, perfectly seasoned homestyle chicken bone broth with curly egg noodles, sliced carrots, celery and herbs.
Vine-ripened pear tomatoes pureed with fresh cream for a velvety smooth flavor accented by hints of red pepper and oregano and topped with black pepper and sea salt croutons.
Romaine and crisp mixed greens tossed in a sweet white balsamic vinaigrette, topped with grilled chicken, grape tomatoes, red onions, toasted pecan pieces, feta, and apple chips.
Romaine and crisp mixed greens tossed in Green Goddess dressing, topped with grilled chicken, grape tomatoes, and pickled red onions, fresh avocado, applewood smoked bacon and a hard-boiled egg.
Romaine tossed in ranch dressing, with grilled chicken and drizzled with chipotle aioli, topped with fresh avocado, grape tomatoes, roasted corn, fresh cilantro, and blue corn tortilla strips.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, grilled chicken, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine tossed in Greek dressing, topped with grilled chicken, grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine tossed in Greek dressing, topped with grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine and crisp mixed greens tossed in ranch dressing, topped with grape tomatoes, pickled red onions, applewood smoked bacon, feta, and a hard-boiled egg.
A salty, chocolaty, caramel confection big enough to share. A large cookie with semi-sweet chocolate, milk chocolate, caramel pieces, pretzels and then topped with flake salt.
Soft and smooth with hints of citrus, roasted nut and chocolate. A blend of Central and South American beans. Light bodied with a bright sweetness. Freshly ground in cafes.
Subtle nutty tones with wonderful coffee flavor. Serves 10. Brewed fresh, so please allow additional 15 min./tote to prepare your order. 120 fl oz per tote.
Rich, bold and full-bodied, balanced with a smoky accent and sweet chocolate notes. Harvested from Central and South America. Serves 10. 120 fl oz per tote.
Carefully roasted from Arabica beans and freshly brewed. Brewed fresh, so please allow additional 15 min./tote to prepare your order. Serves 10. 120 fl oz per tote.
Smoked, pulled chicken, scrambled egg, white cheddar, zesty sweet Peppadew peppers, fresh avocado and cilantro, salt and pepper, and chipotle aioli on Ciabatta.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
Explore offerings from Panera Bread on 9542 Destiny USA Drive in Syracuse, with popular we’re here to help when and where you need us. available at this location.
We deliver your Panera favorites right to your door with contactless delivery. Just tell us where to leave your meal in the “Delivery Instructions” box when placing your order.
Panera pizza is here! Unbox the new flatbread pizzas in three varieties: margherita, chipotle chicken & bacon, and cheese. Pick it up, have it delivered, or grab it through the drive through for lunch or dinner.
Worst Panera in the area! Please go to Cicero or other location to get your moneys worth. On a Monday evening, they take more than 30 mins to prepare an order. I get it, it can be busy so I understand. Then they mess up the order and you are missing items which is unacceptable!
CS
Chaka Stewart
Jul 10, 2026
1.0
I ordered a grilled cheese sandwich and it was sticking to the wrapper. I explained to Joe, who was the manager and he said that usually happens but OK have the sandwich was stuck to the paper and then I ordered a danish with my order and it’s so flaky and falling apart in her heart he told me it was made this morning My issue was not resolved
SF
sara fertig
Jul 8, 2026
2.0
Super Slow service, possibly understaffed. Extremely dirty Panera, had a hair in my sandwich also. Needs a remodel…
TS
Tammy-Sue Seedgrazer
Jun 2, 2026
5.0
I GOT GOOD DEALS FROM THE MOBILE APP
JT
Jonathan Tate
May 23, 2026
5.0
Broccoli cheddar soup was amazing as it always is. Ostmeal raisin cookie with berries is delicious. Restaurant could have been somewhat cleaner. Staff was somewhat less friendly than other Paneras.
Does Panera Bread at 9542 Destiny USA Drive accept reservations?
No, Panera Bread does not accept reservations at this location.
What are the operating hours of Panera Bread Syracuse?
Panera Bread is open Monday through Saturday from 9:00 AM to 7:30 PM, and Sunday from 9:00 AM to 6:00 PM.
Does Panera Bread offer delivery and pick-up services?
Yes, Panera Bread offers both delivery and pick-up services, including Rapid Pick-Up and delivery during their regular hours.
Can I order from Panera Bread Syracuse online or through an app?
Yes, you can order online for Rapid Pick-Up or delivery via their website or by using the Panera Bread app available on the Apple App Store.
What payment methods are accepted at Panera Bread Syracuse?
Panera Bread accepts payment via American Express, Cash, Discover, Mastercard, and Visa.
What types of meals are served at Panera Bread at Destiny USA Drive?
They serve breakfast, lunch, brunch, and dinner featuring soups, salads, sandwiches, and freshly baked artisan breads.
Is Panera Bread Syracuse a casual dining place?
Yes, the dress code is casual, making it a comfortable spot for dining.
Which nearby attractions could I visit before or after dining at Panera Bread Syracuse?
Nearby attractions include Glowgolf, an amusement park and miniature golf course, and Carousel playground, great for family outings.
What other dining options are close to Panera Bread at Destiny USA Drive?
Nearby dining options include 110 Grill (American and cocktail bar), China Express (Asian cuisine), Charleys Cheesesteaks (fast food sandwich shop), and Taco Bell (fast food).
Are there shopping opportunities near Panera Bread Syracuse?
Yes, nearby stores include 99 Cent City, Larger Than Life & Comics Toys bookstore, Motherhood Maternity, The Children’s Place, and Hollister Co., providing various shopping experiences.
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