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Panera Bread Indianapolis welcomes guests to our café with warm hospitality and quality ingredients. We serve a variety of menu favorites for breakfast, lunch, and dinner—including fresh coffee, bakery items, salads, soups, and sandwiches—crafted to help you feel good about what you’re enjoying. Whether you’re dining in while enjoying complimentary Wi‑Fi, ordering online for Rapid Pick‑Up, enjoying delivery, or planning catering for a large group, Panera Bread Indianapolis is here to make your day a little better. Food as it should be.
Explore offerings from Panera Bread on 5335 E Southport Road in Indianapolis, with popular sandwiches, soups & mac, salads, and pastries & sweets available at this location.
Smoked, pulled chicken raised without antibiotics, smoked Gouda, fresh avocado and cilantro, zesty sweet Peppadew™ peppers and chipotle sauce on Black Pepper Focaccia.
Smoked, pulled chicken, fresh mozzarella, vine-ripened tomatoes, red onions, fresh basil, chipotle aioli, salt and pepper on our Black Pepper Focaccia.
Black Forest ham, soppressata, provolone, romaine, red onion, sliced pepperoncini peppers, garlic aioli, and Greek dressing on our toasted French Baguette.
Melty fresh mozzarella, vine-ripened tomatoes, chopped basil, crisp romaine & lettuce blend, sprinkled with salt and pepper, and balsamic vinaigrette and garlic aioli drizzle on our Ciabatta.
Oven-roasted turkey breast, applewood smoked bacon with aged white cheddar, crisp mixed greens, vine-ripened tomatoes, sprinkled with salt and pepper, and our Signature Bravo sauce drizzle on our Tomato Basil Miche.
Oven roasted turkey breast, aged white cheddar, crisp mixed greens, vine-ripened tomatoes, red onions, garlic aioli, salt and pepper on our Country Rustic Sourdough.
A rich chunky chili with beef, kidney beans, fire roasted tomatoes and green chili peppers, simmered in a broth flavored with a blend of chilis, and cilantro.
Tender pieces of white-meat chicken simmered in a rich, perfectly seasoned homestyle chicken bone broth with curly egg noodles, sliced carrots, celery and herbs.
Vine-ripened pear tomatoes pureed with fresh cream for a velvety smooth flavor accented by hints of red pepper and oregano and topped with black pepper and sea salt croutons.
Romaine and crisp mixed greens tossed in a sweet white balsamic vinaigrette, topped with grilled chicken, grape tomatoes, red onions, toasted pecan pieces, feta, and apple chips.
Romaine and crisp mixed greens tossed in Green Goddess dressing, topped with grilled chicken, grape tomatoes, and pickled red onions, fresh avocado, applewood smoked bacon and a hard-boiled egg.
Romaine tossed in ranch dressing, with grilled chicken and drizzled with chipotle aioli, topped with fresh avocado, grape tomatoes, roasted corn, fresh cilantro, and blue corn tortilla strips.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, grilled chicken, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine and crisp mixed greens tossed in Greek Dressing, topped with our whole grain blend, hummus, feta, red onions, zesty sweet Peppadew peppers, sliced cucumbers, and a sprinkle of shawarma seasoning.
Romaine tossed in Greek dressing, topped with grilled chicken, grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine tossed in Greek dressing, topped with grape tomatoes, feta, sliced cucumbers, red onions, kalamata olives, sliced pepperoncini peppers, salt and pepper.
Romaine and crisp mixed greens tossed in ranch dressing, topped with grape tomatoes, pickled red onions, applewood smoked bacon, feta, and a hard-boiled egg.
A salty, chocolaty, caramel confection big enough to share. A large cookie with semi-sweet chocolate, milk chocolate, caramel pieces, pretzels and then topped with flake salt.
Soft and smooth with hints of citrus, roasted nut and chocolate. A blend of Central and South American beans. Light bodied with a bright sweetness. Freshly ground in cafes.
Subtle nutty tones with wonderful coffee flavor. Serves 10. Brewed fresh, so please allow additional 15 min./tote to prepare your order. 120 fl oz per tote.
Rich, bold and full-bodied, balanced with a smoky accent and sweet chocolate notes. Harvested from Central and South America. Serves 10. 120 fl oz per tote.
Carefully roasted from Arabica beans and freshly brewed. Brewed fresh, so please allow additional 15 min./tote to prepare your order. Serves 10. 120 fl oz per tote.
Smoked, pulled chicken, scrambled egg, white cheddar, zesty sweet Peppadew peppers, fresh avocado and cilantro, salt and pepper, and chipotle aioli on Ciabatta.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
A meal to feed the whole family, including 4 half sandwiches, 1 whole salad, 1 group soup, 1 whole French baguette and 4 Chocolate Chipper Cookies. Serves 4-6.
Explore offerings from Panera Bread on 5335 E Southport Road in Indianapolis, with popular we’re here to help when and where you need us. available at this location.
We deliver your Panera favorites right to your door with contactless delivery. Just tell us where to leave your meal in the “Delivery Instructions” box when placing your order.
Panera pizza is here! Unbox the new flatbread pizzas in three varieties: margherita, chipotle chicken & bacon, and cheese. Pick it up, have it delivered, or grab it through the drive through for lunch or dinner.
The floor was so dirty that my shoes were sticking to it and I don’t even think I would touch the self ordering screen because it was filthy. They weren’t even that busy, there was no reason why that place could not be clean
AA
Alan
4 days ago
1.0
Literally the most heartless store I have ever encountered. My sick mother requested broccoli and cheddar soup and they would not sell it to me because they said it was too late. Now she will starve, and I am heartbroken. I feel like a complete failure.
SR
savannah royer
Sep 26, 2026
1.0
if i could leave zero stars i would. there was hair in my coffee that was not mine. i pull on it thinking it was on the outside of the cup to discover it was on the inside. i tell an employee and proceed to hear the lady that made it talk to her other coworker in front of me saying that the hair is “on it.. not in it!” loudly so i would hear. when i showed her coworker i pulled on the hair to show him it was clearly in the drink. if it was just on it i would have pulled it off and gone about my day. now that i know how rude the workers are i wouldnt be suprised if she put more hair in the one she remade. the employees are a joke.
AD
Anna M Dujan
Sep 13, 2026
1.0
I’ve never left a bad review for a restaurant before. The new frittata at almost 6 dollars should be an embarrassment to you. There’s one egg and a little bacon and cheese on there. It hardly even fills the bottom of the paper container it’s in. Also, why is it always freezing in there! The windows are fogged constantly and the music is always very very loud. It’s not this way in another. The only redeeming quality is the efficiency of the staff most of the time.
MS
Manbir singh
Sep 10, 2026
1.0
⭐ Very disappointing experience at the Panera Bread on Southport Road.
We ordered three Chipotle Avocado Melt sandwiches, but all three were made without avocado. When we brought this to the manager’s attention, instead of simply remaking the sandwiches correctly, she brought them back and tried to give us avocado on the side.
I politely asked if she could please put the avocado inside the sandwiches for us, since that is how the sandwiches were supposed to be made. Instead of apologizing for the mistake and fixing the order professionally, the manager showed a very rude and disrespectful attitude toward me in front of other customers.
Mistakes with food can happen, and I completely understand that. What made this a really bad experience was the manager’s attitude and the way the situation was handled. I felt embarrassed and disrespected in front of other customers. As a manager, I would expect better customer service, professionalism, and at least a simple apology when an order is made incorrectly.
Very disappointed with the management and customer service at this location.
What are the operating hours for Panera Bread on weekdays?
Panera Bread is open from 6:00 AM to 10:00 PM Monday through Saturday, and from 7:00 AM to 10:00 PM on Sundays.
Can I order delivery from Panera Bread?
Yes, Panera Bread offers delivery service every day during its operating hours.
What meal options are available at this Panera Bread location?
Panera Bread serves breakfast, lunch, brunch, and dinner with a focus on quality soups, salads, and sandwiches.
Does Panera Bread have a drive-thru and pick-up services?
Yes, this Panera Bread location offers drive-thru and pick-up services for your convenience.
What payment methods are accepted at Panera Bread?
Panera Bread accepts American Express, Cash, Discover, MasterCard, and Visa.
Can I order Panera Bread through their mobile app?
Yes, you can order using the Panera Bread app available on the Apple App Store for quick and easy ordering.
What nearby dining options are close to Panera Bread on E Southport Road?
Nearby dining options include Domino's Pizza, Thai Charm, Mr. Wok, Jimmy John's, Taco Bell, Rally's, Chick-fil-A, and Ben's Soft Pretzels, offering a variety of cuisines from pizza to Asian and fast food.
Are there nearby places to grab coffee or a snack near Panera Bread?
Yes, besides Panera Bread itself, Biggby Coffee and another Panera Bread café are nearby if you're looking for coffee or a quick bite.
What nearby services and stores could I visit around Panera Bread?
Nearby services include the United States Postal Service, multiple credit unions like Teachers Credit Union and Everwise Credit Union, as well as retail stores such as La-Z-Boy Furniture Galleries and Sherwin-Williams hardware store.
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