Pizza RestaurantRestaurant Delivery ServiceTake Out RestaurantFast Food RestaurantDomino's Pizza
Looking for great pizza in Indianapolis? At Domino’s, we’re passionate about bringing you the best pizza experience, whether you're carrying out or ordering pizza delivery. Whether you’re craving thin, foldable New York Style pizza or a thick, Handmade Pan pizza, Domino’s has you covered. Or try our delicious, cheesy Parmesan Stuffed Crust pizza today! We offer more than just mouthwatering pizza—dishes like our fan-favorite mac and cheese, salads, pasta, and chicken wings will satisfy all your needs. We’ll give you great value with our unbeatable deals, making it easy to enjoy more for less. Wherever you are, the Domino's Pizza near you is here to satisfy your cravings with taste and quality. Order from 9935 E. 21st Street .
Explore offerings from Domino's Pizza on 9935 E. 21st Street in Indianapolis, with popular mix and match, pizza, breads, and chicken available at this location.
Test Menu data- all locations
97 items
Mix and Match
2-Topping Domino
$6.99
Our premium, buttery flavored pan dough encrusted with real Parmesan cheese, and baked in a rectangular pan to create a crispy Parmesan Detroit Style crust. Topped with two layers of cheese and your favorite sauce and up to 3 toppings then finished with our signature garlic seasoning.
2-Topping Medium Pizza
$6.99
A custom pizza made to order. Choose from any of our delicious crust styles, excluding Handmade Pan or Paremsan Crust.
Parmesan Bread Bites
$6.99
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan.
Stuffed Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Pepperoni Stuffed Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese and pepperoni - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Spinach & Feta Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese, fresh spinach and Feta cheese - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Bacon & Jalapeño Cheesy Bread
$6.99
Our oven-baked breadsticks are stuffed with cheese, smoked bacon and jalapeno peppers - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an addional charge.
Boneless Chicken
$6.99
Breaded chicken made with 100% whole white breast meat. Choose one or more dipping cups for an additional charge.
Hot Buffalo Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with hot buffalo sauce, ranch, a blend of cheese made with mozzarella and cheddar, and feta.
Sweet BBQ Bacon Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with sweet and smoky honey BBQ sauce, a blend of cheese made with mozzarella and cheddar, and crispy bacon.
Crispy Bacon & Tomato Loaded Chicken
$6.99
Tender bites of breaded chicken made with 100% whole breast white meat topped with garlic Parmesan sauce, a blend of cheese made with mozzarella and cheddar, crispy bacon and tomato.
Spicy Jalapeno-Pineapple Loaded Chicken
$6.99
Tender bites of lightly breaded, 100% whole breast white meat chicken, topped with sweet and spicy mango-habanero sauce, a blend of cheese made with mozzarella and cheddar, jalapeno and pineapple.
5-Cheese Mac & Cheese
$6.99
Our take on the classic. Penne pasta and a blend of cheddar, American, Parmesan-Asiago, mozzarella blend and Alfredo sauce, oven baked to creamy, bubbly perfection.
Spicy Buffalo 5-Cheese Mac & Cheese
$6.99
Our creamy, oven baked 5-cheese Mac & Cheese drizzled with buffalo sauce for a spicy kick.
Chicken Alfredo
$6.99
Grilled chicken breast and creamy Alfredo sauce mixed with penne pasta and baked to perfection.
Philly Cheese Steak
$6.99
Tender slices of steak, American and provolone cheeses, fresh onions, fresh green peppers and fresh mushrooms.
Chicken Bacon Ranch
$6.99
Grilled chicken breast topped with smoked bacon, creamy ranch and provolone cheese.
Italian
$6.99
Pepperoni and ham topped with banana peppers, fresh green peppers, fresh onions and provolone cheese.
Chicken Parm
$6.99
Grilled chicken breast, tomato-basil marinara, Parmesan- Asiago and provolone cheeses.
Buffalo Chicken
$6.99
Grilled chicken breast, ranch, fresh onions, hot buffalo sauce, provolone, cheddar and cheese made with 100% real mozzarella.
Classic Garden
$6.99
A crisp and colorful combination of grape tomatoes, red onions, carrots, red cabbage, cheddar cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Chicken Caesar
$6.99
The makings of a classic: roasted white meat chicken, Parmesan cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Cinnamon Bread Bites
$6.99
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Domino's Marbled Cookie Brownie
$6.99
An irresistibly warn and gooey blend of milk chocolate chunk cookie and fudge brownie. This sharable dessert is oven baked at the time of order and cut into 9 pieces.
Chocolate Lava Crunch Cakes
$6.99
Oven-baked chocolate cakes, crunchy on the outside with molten chocolate fudge on the inside.
S’mores Lava Cakes
$6.99
Three decadent oven-baked graham cracker cakes oozing with a chocolatey chip and gooey marshmallow flavored filling. Perfectly topped with a dash of powdered sugar.
Spicy Chicken Bacon Ranch
$9.99
Grilled chicken breast, creamy ranch, smoked bacon, jalapeños, provolone, and cheese made with 100% real mozzarella and finished off with a drizzle of buffalo sauce.
The People's Pizza - Deluxe
$9.99
Savory pepperoni and Italian sausage, fresh green peppers, fresh mushrooms, fresh onions, provolone and cheese made with 100% real mozzarella
ExtravaganZZa
$9.99
Pepperoni, ham, Italian sausage, beef, fresh onions, fresh green peppers, fresh mushrooms and black olives, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
MeatZZa
$9.99
Pepperoni, ham, Italian sausage and beef, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
Honolulu Hawaiian
$9.99
Sliced ham, smoked bacon, pineapple, fresh green peppers, provolone and cheese made with 100% real mozzarella.
Philly Cheese Steak
$9.99
Tender slices of steak, fresh onions, fresh green peppers, fresh mushrooms, provolone and American cheese.
Pacific Veggie
$9.99
Fresh baby spinach, fresh onions, fresh mushrooms, tomatoes, black olives, feta, provolone, cheese made with 100% real mozzarella and sprinkled with a garlic herb seasoning.
Ultimate Pepperoni
$9.99
Two layers of pepperoni sandwiched between provolone, Parmesan-Asiago and cheese made with 100% real mozzarella then sprinkled with oregano.
Memphis BBQ Chicken
$9.99
Grilled chicken breast, honey BBQ sauce, fresh onions, cheddar, provolone and cheese made with 100% real mozzarella
Wisconsin 6-Cheese
$9.99
Feta, provolone, cheddar, Parmesan-Asiago, cheese made with 100% real mozzarella and sprinkled with oregano.
Spinach & Feta
$9.99
Creamy Alfredo sauce, fresh spinach, fresh onions, feta, Parmesan-Asiago, provolone and cheese made with 100% real mozzarella.
Pizza
BYO Domino
Our premium, buttery flavored pan dough encrusted with real Parmesan cheese, and baked in a rectangular pan to create a crispy Parmesan Detroit Style crust. Topped with two layers of cheese and your favorite sauce and up to 3 toppings then finished with our signature garlic seasoning.
Spicy Chicken Bacon Ranch
Grilled chicken breast, creamy ranch, smoked bacon, jalapeños, provolone, and cheese made with 100% real mozzarella and finished off with a drizzle of buffalo sauce.
ExtravaganZZa ™
Pepperoni, ham, Italian sausage, beef, fresh onions, fresh green peppers, fresh mushrooms and black olives, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
MeatZZa™
Pepperoni, ham, Italian sausage and beef, all sandwiched between two layers of provolone and cheese made with 100% real mozzarella.
Philly Cheese Steak
Tender slices of steak, fresh onions, fresh green peppers, fresh mushrooms, provolone and American cheese.
Honolulu Hawaiian
Sliced Ham, smoked bacon, pineapple, fresh green peppers, provolone and cheese made with 100% real mozzarella.
Pacific Veggie
Fresh spinach, fresh onions, fresh mushrooms, fresh onions, provolone and cheese made with 100% real mozzarella.
The People’s Pizza – Deluxe
Savory pepperoni and Italian sausage, fresh green peppers, fresh mushrooms, fresh onions, provolone and cheese made with 100% real mozzarella.
We’ve combined our customers’ most ordered toppings into the perfect deluxe pizza.
Ultimate Pepperoni
Two layers of pepperoni sandwiched between provolone, Parmesan-Asiago and cheese made with 100% real mozzarella, then sprinkled with oregano.
Memphis BBQ Chicken
Grilled chicken breast, fresh onions, provolone, American cheese, cheddar, cheese made with 100% real mozzarella.
Wisconsin 6-Cheese
Feta, provolone, cheddar, Parmesan-Asiago, cheese made with 100% real mozzarella, then sprinkled with oregano.
Spinach & Feta
Creamy Alfredo sauce, fresh spinach, fresh onions, feta, Parmesan-Asiago, provolone and cheese made with 100% real mozzarella.
Build Your Own
A custom pizza made to order. Choose from any of our delicious crust styles, including Handmade Pan or Parmesan Stuffed Crust.
Breads
Parmesan Bread Bites
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan.
Cinnamon Bread Bites
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
Stuffed Cheesy Bread
Our oven-baked breadsticks are stuffed and covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Pepperoni Stuffed Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese and pepperoni - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Spinach & Feta Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese, fresh spinach and Feta cheese - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Bacon & Jalapeño Cheesy Bread
Our oven-baked breadsticks are stuffed with cheese, smoked bacon and jalapeno peppers - covered in a blend of cheese made with 100% real mozzarella and cheddar. Seasoned with a touch of garlic and Parmesan. Add marinara or your favorite dipping cup for an additional charge.
Chicken
Boneless Chicken
Breaded chicken made with 100% whole white breast meat. Choose one or more dipping cups for an additional charge.
Bone-in Wings
Marinated and oven-baked. Customize with your choice of dipping cup.
Hot Buffalo Bone-in Wings
Marinated and oven-baked, then smothered in hot buffalo sauce. Customize with your choice of dipping cup.
Honey BBQ Bone-in Wings
Marinated and oven-baked, then smothered in honey BBQ sauce. Customize with your choice of dipping cup.
Garlic Parmesan Bone-in Wings
Marinated and oven-baked, then smothered in garlic Parmesan sauce. Customize with your choice of dipping cup.
Sweet Mango Habanero Bone-in Wings
Marinated and oven-baked, then smothered in sweet mango habanero sauce. Customize with your choice of dipping cup.
Hot Buffalo Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with hot buffalo sauce, ranch, a blend of cheese made with mozzarella and cheddar, and feta.
Sweet BBQ Bacon Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with sweet and smoky honey BBQ sauce, a blend of cheese made with mozzarella and cheddar, and crispy bacon.
Crispy Bacon & Tomato Loaded Chicken
Tender bites of breaded chicken made with 100% whole breast white meat topped with garlic Parmesan sauce, a blend of cheese made with mozzarella and cheddar, crispy bacon and tomato.
Spicy Jalapeno-Pineapple Loaded Chicken
Tender bites of lightly breaded, 100% whole breast white meat chicken, topped with sweet and spicy mango-habanero sauce, a blend of cheese made with mozzarella and cheddar, jalapeno and pineapple.
Pastas
5-Cheese Mac & Cheese
Our take on the classic. Penne pasta and a blend of cheddar, American, Parmesan-Asiago, mozzarella blend and Alfredo sauce, oven baked to creamy, bubbly perfection.
Spicy Buffalo 5-Cheese Mac & Cheese
Our creamy, oven baked 5-cheese Mac & Cheese drizzled with buffalo sauce for a spicy kick.
Chicken Alfredo
Grilled chicken breast and creamy Alfredo sauce mixed with penne pasta and baked to perfection.
Oven-Baked Sandwiches
Philly Cheese Steak
Tender slices of steak, American and provolone cheeses, fresh onions, fresh green peppers and fresh mushrooms.
Chicken Bacon Ranch
Grilled chicken breast topped with smoked bacon, creamy ranch and provolone cheese.
Italian
Pepperoni and ham topped with banana peppers, fresh green peppers, fresh onions and provolone cheese.
Chicken Parm
Grilled chicken breast, tomato-basil marinara, Parmesan- Asiago and provolone cheeses.
Buffalo Chicken
Grilled chicken breast, ranch, fresh onions, hot buffalo sauce, provolone, cheddar and cheese made with 100% real mozzarella.
Salads
Classic Garden
A crisp and colorful combination of grape tomatoes, red onions, carrots, red cabbage, cheddar cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Chicken Caesar
The makings of a classic: roasted white meat chicken, Parmesan cheese and brioche garlic croutons, all atop a blend of romaine and iceberg lettuce.
Ranch
A flavorful creamy dressing with touches of buttermilk and garlic.
Balsamic
A light dressing with a blend of balsamic vinegar, oil and garlic.
Caesar
A savory dressing with a combination of garlic, anchovy and subtle notes of cheese.
Desserts
Chocolate Lava Crunch Cakes
Oven-baked chocolate cakes, crunchy on the outside with molten chocolate fudge on the inside.
Domino's Marbled Cookie Brownie
An irresistibly warn and gooey blend of milk chocolate chunk cookie and fudge brownie. This sharable dessert is oven baked at the time of order and cut into 9 pieces.
Cinnamon Bread Bites
Handmade from fresh buttery tasting pan dough, drizzled with cinnamon and sugar. Oven baked to perfection. Served with a side of sweet icing for dipping or drizzling.
S’mores Lava Cakes
Three decadent oven-baked graham cracker cakes oozing with a chocolatey chip and gooey marshmallow flavored filling. Perfectly topped with a dash of powdered sugar.
Drinks
Coca Cola®
Available in 20 oz and 2-liter bottles
Diet Coke®
Available in 20 oz and 2-liter bottles
Sprite®
Available in 20 oz and 2-liter bottles
Fanta® Orange
Available in 20 oz and 2-liter bottles
Dasani® Water
Available in 20 oz bottles
Dip Cups
Slice Sauce Dipping Cup
Creamy and zesty with a hint of Parmesan.
Ranch
A creamy buttermilk ranch dressing with hints of garlic and onion.
Blue Cheese
A creamy dressing with bits of aged blue cheese.
Hot Buffalo
Domino's own spicy buffalo sauce.
Honey BBQ
A sweet and smoky BBQ sauce with bold flavor.
Marinara
A sweet tomato sauce blended with garlic, basil and oregano.
Garlic
A buttery garlic sauce.
Sweet Mango Habanero
A perfect blend of sweet and spicy in one sauce.
Sweet Icing
A thick sweet icing with a hint of vanilla.
Reviews
3.2
498 reviews
5 stars
209
4 stars
58
3 stars
39
2 stars
29
1 star
163
SB
Shelley Bates
May 21, 2026
5.0
Always friendly and fast!
DW
David Wilson
Apr 15, 2026
5.0
Their people are always kind. The pizza is always hot. The prices are ideal for feeding a bunch of kids
CC
Chris Croy
Apr 8, 2026
1.0
i placed a order and that shitty excuse of a manager nicole is a disgrace to the company if you don’t like your job then don’t go in i definitely won’t be ordering from there again and i enjoy them but that attitude is not tolerated
TS
Taffy Von Sweetland
Apr 4, 2026
5.0
Good, 1st time eating since the 90s , not bad!
TB
Trelaine Bayer
Aug 24, 2023
4.0
We ordered the hot wings, garlic knots with marinara, and a pepperoni pizza - the wings were great, spicy meaty, juicy with a crispy-saucy outside, was more than my white mom bargained for on the spiciness though, although she did thoroughly enjoy it (a 4.7/5) :). The pizza was a bit dry, the sauce ratio could be better or they could use a garlic butter on the crust; the cheese and pepperoni ratios were okay and the pizza, overall, was okay, like 3.5/5. The garlic bites were crunchy on the outside and soft on the inside but they were almost a bit too airy- they felt more hollow than airy; although, I did go into it wanting a doughy, bready breadstick-like finger food (something filling that I could eat with one hand), so maybe I went in with an unfair expectation? Either way, they lived up to the 'garlic knot' name and I could eat them with one hand without too much of a mess but they were much smaller than I originally had wanted - a warning as well, they were oddly sweet with the butter adding a saltiness that definitely got better over time but didn't make much sense at first as the two flavors stand out from one another. I'd give the knots a 2.8/5 as I've had better garlic knots that set my standards of what I expect of garlic breads, twists, and knots. Hope this helps some of y'all when picking a place!
Ps. The location we went to was open till 12am, for all of you late-nighters, and they switch to curbside and online ordering after a certain time, but they didn't send us a message when our food was actually ready (they let us know our order was received and that it was in the oven, though).
What types of pizza crust options are available at Domino's Pizza in Indianapolis?
Domino's offers New York Style, Handmade Pan, and Parmesan Stuffed Crust pizzas.
What are the operating hours for delivery at Domino's Pizza located at 9935 E. 21st Street?
Delivery is available from 10:00 AM to midnight Sunday through Thursday, and until 1:00 AM on Friday and Saturday.
Can I order pizza for curbside pickup or no-contact delivery?
Yes, Domino's offers curbside pickup and no-contact delivery along with standard delivery.
What payment methods does Domino's Pizza accept?
They accept Afterpay, American Express, Android Pay, Apple Pay, Bitcoin, Cash, Check, Contactless Payment, Diners Club, Discover, Financing, Invoice, Klarna, MasterCard, PayPal, Samsung Pay, Traveler's Check, Visa, and Zelle.
Where can I view the Domino's Pizza menu or place an order online?
You can view the menu and place orders online at https://www.dominos.com/en/pages/order/menu for the menu and https://www.dominos.com/en/restaurants for ordering.
What are some nearby pizza places to Domino's Pizza at 9935 E. 21st Street, Indianapolis?
Nearby pizza places include Pizza Hut, O B's Pizza Pub & Eatery, More Than Just Pizza, and Just Pizza.
Are there any nearby gas stations around Domino's Pizza on E. 21st Street?
Yes, there are several gas stations nearby including Exxon, Amoco, East Side Marathon, and J and V Automotive Repair which also offers gas services.
What other dining options are available near Domino's Pizza at this location?
Nearby dining options include New York Gourmet Deli, My Taco Stop Food Truck, Hooks Fish & Chicken Plus, and Mauri Brother's Chicken & Fish.
What are the operating hours for takeout at this Domino's Pizza location?
Takeout hours are from 10:00 AM to midnight Sunday through Thursday, and until 1:00 AM on Friday and Saturday.
Is Domino's Pizza in Indianapolis suitable for vegetarians?
Yes, Domino's in Indianapolis serves vegetarian dishes as part of their menu offerings.
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