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DeSano Pizzeria Napoletana

4.6
(272 reviews)
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Business Details

635 U.S. Highway 1, North Palm Beach, FL
33408, United States
(561) 337-4996
https://desanopizza.com/desanonpb

About

Pizza Restaurant

Details

  • DeliveryAvailable
  • TakeoutAvailable
  • Curbside pickupAvailable

Location

DeSano Pizzeria Napoletana
635 U.S. Highway 1, North Palm Beach, FL
33408, United States

Hours

Monday11:30 AM - 9:00 PM
Tuesday11:30 AM - 9:00 PM
Wednesday11:30 AM - 9:00 PM
Thursday11:30 AM - 9:00 PM
Friday11:30 AM - 9:00 PM
Saturday11:30 AM - 9:00 PM
Sunday11:30 AM - 9:00 PM

Menu

1 menu · 64 items

Explore offerings from DeSano Pizzeria Napoletana on 635 U.S. Highway 1 in North Palm Beach, with popular 12" napoli - tradizionale, 12" napoli - specialita, 16" grande - tradizionale, and 16" grande - specialita available at this location.

Full Menu

64 items

Reviews

4.6
272 reviews
5 stars
233
4 stars
13
3 stars
3
2 stars
10
1 star
13
  • AA
    Andrew
    6 days ago
    5.0
    We have been enjoying DeSano for quite a while and I felt compelled to share my thoughts. The decor is simple, casual, and inviting. The open kitchen with its three 800 degree wood fire Italian ovens and the stockpile of wood below them provide a great look and feel. You can literally watch your pizza being made from spreading the dough to it coming out of the oven. We ordered two salads for four of us. The Italian Chopped and the Insalata Rustica. Both were delicious and plentiful! For pizza, we shared the Doppio Pepperoni which featured both wider thinner sliced traditional pepperoni as well as slightly thicker nickel pepperoni which added a great level of texture to the pizza. We also shared the Lasagna pizza featuring San Marzano tomato sauce along with meatballs, ricotta, buffalo mozzarella and more and it really delivers a delicious lasagna experience as a pizza. Both pizzas tasted and felt like Italy and the conversation was steered toward reminiscing about being and eating in Italy! One of the best parts of our stay was our server, Kristin, who has taken care of us on multiple visits. She always answers questions with great knowledge of the menu and gives great recommendations if you are struggling to decide between menu choices! Because of the quality and freshness of the ingredients, you feel like you do when leaving a restaurant in Italy, not overloaded or bloated but happy and comfortable! And talking about when to go back next!
  • CR
    Cherish Ramkissoon
    Aug 27, 2026
    4.0
    Anytime I’m in the mood for pizza I go to Desano’s! Flavors are fresh, the spicy oil with the garlic is YUM!
  • RR
    Raechel
    Aug 20, 2026
    5.0
    This is the new pizza place to head over to and grab takeout from!! ALL the menu items I have tried have been phenomenal. ALL fresh and all-natural ingredients. The staff has been professional and friendly! Dine in, delivery, or takeout! There is patio seating as well! Great location, tucked away on US 1 in North Palm Beach!!!
  • RJ
    Raechel Johnson
    Aug 18, 2026
    5.0
    **DON’T SLEEP ON THIS PIZZA PLACE! ** I’ve ordered delivery from here several times, and I finally decided to dine in — and after trying multiple things on the menu, I can honestly say EVERYTHING has been absolutely delicious! What really sets this place apart is the quality of the ingredients and the care that goes into the food. They use San Marzano tomatoes fresh, quality ingredients, and everything is made by hand — nothing comes out of a freezer! You can absolutely taste the difference. And because they’re using quality ingredients and making everything fresh, you don’t walk away with that heavy, overly-full feeling that you sometimes get after eating at other pizza places. It just tastes fresh, flavorful, and incredibly well made. The restaurant itself is also super clean, and the staff is VERY friendly and welcoming, which makes the whole experience even better. I’m genuinely impressed with this place and will definitely keep coming back. If you haven’t tried it yet....you need to go! Whether you order delivery, dine in, or take-out... you’re missing out if you’re sleeping on this spot! Great ingredients. Handmade food. Clean restaurant. Friendly people. And seriously delicious pizza. What more could you ask for?
  • NV
    Nicole Vacca
    Aug 9, 2026
    5.0
    Came here for the first time and had a spectacular Margherita pizza. My hubby said it's very similar to the quality of the pizza he tried in Rome. Prices are reasonable for the quality. Friendly service and lots of seating available. We also had the Nutella pizza for dessert. It was our first time ever trying this dessert pizza so we weren't sure what to expect but it was tasty, pretty sweet. Will definitely return. Our new go-to pizza spot!
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